Abstract: The present application provides immune cells (such as T cells) comprising a chimeric antibody-T cell receptor (TCR) construct (caTCR) and a chimeric signaling receptor (CSR) construct. The caTCR comprises an antigen-binding module that specifically binds to a target antigen and a T cell receptor module (TCRM) capable of recruiting at least one TCR-associated signaling molecule, and the CSR comprises a ligand-binding domain that specifically binds to a target ligand and a co-stimulatory signaling domain capable of providing a stimulatory signal to the immune cell. Also provided are methods of making and using these cells.

Abstract: Disclosed is a cardiac diastolic function assessment method applicable to the field of cardiac monitoring. The method comprises: acquiring vibration information of the thoracic cavity body surface of an object in a noninvasive manner; preprocessing the vibration information to generate hemodynamic-related information; determining a target wave group on the basis of the hemodynamic-related information; determining the highest peak on the target wave group, determining a rising edge amplitude before the highest peak as a first characteristic value, and determining, as a second characteristic value, an amplitude between the highest peak and the subsequent lowest valley; and generating an indicating parameter on the basis of the first characteristic value and the second characteristic value, and assessing a cardiac diastolic function of the object on the basis of the indicating parameter.

Abstract: A cardiac diastolic function assessment method, for use in the field of cardiac monitoring. The method comprises: noninvasively acquiring vibration information of the thoracic body surface of a subject; preprocessing the vibration information to generate hemodynamics-related information; determining a first parameter and a second parameter on the basis of the hemodynamics-related information; generating an indicating parameter on the basis of the first parameter and of the second parameter, and assessing the cardiac diastolic function of the subject on the basis of the indicating parameter.

Abstract: A method for evaluating cardiac diastolic function, which applies to the field of cardiac monitoring. The method comprises: obtaining vibration information of the surface of the thoracic cavity of a subject by means of one or more optical fiber sensors; preprocessing the vibration information to generate hemodynamic related information; performing high-frequency component extraction on the hemodynamic related information to generate high-frequency component information; determining a first feature value and a second feature value based on the hemodynamic related information and the high-frequency component information; generating indicating parameters based on the first feature value and the second feature value, and evaluating the cardiac diastolic function of the subject based on the indicating parameters.

Abstract: A foldable sunshade including a shading board body and a fixed part, two or more than two vertical folding lines which are distributed along the transverse direction of the shading board body and run through the vertical direction of the shading board body are arranged on the shading board body, and the shading board body is divided into a plurality of folding units by every two adjacent vertical folding lines and two transverse sides of the shading board body, or one vertical folding line, one vertical side of the shading board body and two transverse sides of the shading board body; two transverse folding lines running through the transverse direction of each folding unit are further arranged at the center of each folding unit, and the two transverse folding lines are symmetrically distributed by taking the transverse center line of the shading board body as a symmetry axis.

Abstract: The invention discloses a toll road network traffic information collection and guidance system based on a route identification system, comprising toll road exit and entry toll lane systems, a networked toll center system, a 5.8 G route identification station, a 5.8 G route identification station monitoring system, a dual-frequency pass card for MTC vehicles, an OBU and a non-cash payment card for ETC vehicles, an in-vehicle multimedia terminal and a traffic information processing system. Collection of route identification, traffic information and vehicle driving state information, and traffic information pushing are implemented using the 5.8 GHz route identification station, the dual-frequency pass card and OBU containing a Bluetooth module and an OBU, and the in-vehicle multimedia terminal; processing and predication of information such as travel time, traffic flow, travel velocity, traffic state, and vehicle location on toll road sections are implemented using a method of combining cloud computing with 5.