Abstract: Disclosed are compositions for targeting 0TUD7A, the compositions having a component sufficient to block and/or reduce OTUD7A-mediated deubiquitination of EWS-FLI1 in a cell. The component can be 7Ai and variants thereof. The compositions can be used to treat Ewing sarcoma (EWS). Methods of using the disclosed compositions are also disclosed, including methods of treating EWS in a subject.

Abstract: A control method for a smart clothes treatment system, solving the problem that an existing linkage method is more suitable for application to a system of associated home appliances that work with the same operating parameters and the linkage mobility and the degree of intelligence are not good. The control method of the smart clothes treatment system can automatically recommend care parameter information of a clothes care device according to washing parameter information of a clothes washing device, so that the clothes care device can directly operate on the basis of the recommended care parameter information. The control method can be appliable to a combination of linkage home appliances having different types of operating parameters such as the clothes washing device and the clothes care device, so that multiple home appliances having a large difference in operating parameters can perform linkage operation on the basis of a specific matching scenario.