Patents by Inventor Pengfei You

Pengfei You has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quantitative detection method for snake venom thrombin-like enzyme (SVTLE)
    Patent number: 11584948
    Abstract: The present invention relates to the technical field of chemical analysis and quantitative detection, in particular to a quantitative detection method for snake venom thrombin-like enzyme (SVTLE) from Agkistrodon halys pallas. The quantitative detection method for the SVTLE includes the following steps of taking a reference substance of marker peptide for the SVTLE from Agkistrodon halys pallas with an amino acid sequence of LDSPVSNSAHIAPLSLPSSAPSVGSVCR, and preparing a series of reference solutions with different concentrations; adding the reference solutions in test solutions respectively for enzymolysis, and then taking a supernatant after enzymolysis as a series of solutions to be detected; and adding the solutions to be detected in a liquid chromatogram-mass spectrometer, and then selecting a qualitative ion pair and a quantitative ion pair to detect contents of marker peptide in the solutions to be detected.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: February 21, 2023
    Assignees: Shandong Institute for Food and Drug Control, Shandong University, Avanc Pharmaceutical Co., Ltd
    Inventors: Feng Shi, Liping Gong, Ruiqing Xian, Lianli Chi, Weijian Wang, Baojian Hang, Congcong Wang, Pengfei You, Hongming Du
  • QUANTITATIVE DETECTION METHOD FOR SNAKE VENOM THROMBIN-LIKE ENZYME (SVTLE)
    Publication number: 20220033873
    Abstract: The present invention relates to the technical field of chemical analysis and quantitative detection, in particular to a quantitative detection method for snake venom thrombin-like enzyme (SVTLE) from Agkistrodon halys pallas. The quantitative detection method for the SVTLE includes the following steps of taking a reference substance of marker peptide for the SVTLE from Agkistrodon halys pallas with an amino acid sequence of LDSPVSNSAHIAPLSLPSSAPSVGSVCR, and preparing a series of reference solutions with different concentrations; adding the reference solutions in test solutions respectively for enzymolysis, and then taking a supernatant after enzymolysis as a series of solutions to be detected; and adding the solutions to be detected in a liquid chromatogram-mass spectrometer, and then selecting a qualitative ion pair and a quantitative ion pair to detect contents of marker peptide in the solutions to be detected.
    Type: Application
    Filed: July 30, 2021
    Publication date: February 3, 2022
    Applicants: Shandong Institute for Food and Drug Control, Shandong University, Avanc Pharmaceutical Co.,Ltd
    Inventors: Feng Shi, Liping Gong, Ruiqing Xian, Lianli Chi, Weijian Wang, Baojian Hang, Congcong Wang, Pengfei You, Hongming Du