Patents by Inventor Pengli Yu

Pengli Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically engineered bacterium for treatment of breast cancer, method for constructing the bacterium, and applications thereof
    Patent number: 9816083
    Abstract: The current invention discloses a genetically engineered bacterium used for the treatment of breast cancer. The said bacterium is attenuated Salmonella typhimurium VNP20009 with cloned L-methioninase gene. The method for constructing this genetically engineered bacterium and the application thereof are also disclosed herein. In the current invention, our biologic drug for the treatment of breast cancer is a type of safe, non-toxic new drug with anti-tumor activity. It can highly express methioninase through recombinant DNA technology using attenuated Salmonella typhimurium VNP20009 as a carrier, which has a strong anti-tumor activity and can meet the needs. The preparation method is simple and easy to operate, showing good application prospect.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: November 14, 2017
    Assignee: NANJING SINOGEN BIOTECH & PHARMACEUTICAL INC.
    Inventors: Yan Lin, Sujin Zhou, Allan Zhao, Xiaoxi Li, Pengli Yu, Fanghong Li
  • GENETICALLY ENGINEERED BACTERIUM FOR TREATMENT OF BREAST CANCER, METHOD FOR CONSTRUCTING THE BACTERIUM, AND APPLICATIONS THEREOF
    Publication number: 20150376593
    Abstract: The current invention discloses a genetically engineered bacterium used for the treatment of breast cancer. The said bacterium is attenuated Salmonella typhimurium VNP20009 with cloned L-methioninase gene. The method for constructing this genetically engineered bacterium and the application thereof are also disclosed herein. In the current invention, our biologic drug for the treatment of breast cancer is a type of safe, non-toxic new drug with anti-tumor activity. It can highly express methioninase through recombinant DNA technology using attenuated Salmonella typhimurium VNP20009 as a carrier, which has a strong anti-tumor activity and can meet the needs. The preparation method is simple and easy to operate, showing good application prospect.
    Type: Application
    Filed: February 27, 2014
    Publication date: December 31, 2015
    Applicant: Nanjing Sinogen Biotech & Pharmaceutical Inc.
    Inventors: Yan Lin, Sujin Zhou, Allan Zhao, Xiaoxi Li, Pengli Yu, Fanghong Li