Patents by Inventor Penina Feibush

Penina Feibush has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for synthesizing phosphonic and phosphinic acid compounds
    Patent number: 8222431
    Abstract: The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: July 17, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Luigi Anzalone, Daniel J. Pippel, Neelakandha S. Mani, Penina Feibush, Ilias K. Dorziotis, Stefan Horns, Frank J. Villani, Jr.
  • NOVEL CRYSTALS AND PROCESS OF MAKING 5-(-METHYL)-2-METHOXY-BENZOIC ACID
    Publication number: 20110263868
    Abstract: The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.
    Type: Application
    Filed: July 1, 2011
    Publication date: October 27, 2011
    Inventors: Luigi Anzalone, Frank J. Villani, Christopher A. Teleha, Penina Feibush, Barry Fegely
  • Crystals and process of making 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1H-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid
    Patent number: 7994206
    Abstract: The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.
    Type: Grant
    Filed: July 7, 2008
    Date of Patent: August 9, 2011
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Luigi Anzalone, Frank J. Villani, Christopher A. Teleha, Penina Feibush, Barry Fegely
  • PROCESS FOR THE PREPARATION OF CHYMASE MODULATORS
    Publication number: 20100145075
    Abstract: The present invention is a process for the preparation of chymase modulators, useful in the treatment of inflammatory and serine protease mediated disorders.
    Type: Application
    Filed: October 29, 2009
    Publication date: June 10, 2010
    Inventors: Luigi Anzalone, Penina Feibush, Ilias Konstantinos Dorziotis, Xun Li, Frank J. Villani
  • PROCESS FOR THE PREPARATION OF PROTECTED L ALANINE DERIVATIVES
    Publication number: 20100145090
    Abstract: The present invention is directed to a novel process for the preparation of protected L-alanine derivatives, useful as intermediates in the synthesis of compounds useful as mu/delta opioid modulators.
    Type: Application
    Filed: October 27, 2009
    Publication date: June 10, 2010
    Inventors: Luigi ANZALONE, Penina FEIBUSH, Frank J. VILLANI
  • Process for synthesizing phosphonic and phosphinic acid compounds
    Publication number: 20090124801
    Abstract: The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
    Type: Application
    Filed: October 16, 2008
    Publication date: May 14, 2009
    Inventors: Luigi Anzalone, Daniel J. Pippel, Neelakandha S. Mani, Penina Feibush, Ilias K. Dorziotis, Stefan Horns, Frank J. Villani, JR.
  • NOVEL CRYSTALS AND PROCESS OF MAKING 5-(-METHYL)-2-METHOXY-BENZOIC ACID
    Publication number: 20090018179
    Abstract: The present invention relates to a novel crystals of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid and methods of making the zwitterion of 5-({[2-amino-3-(4-carbamoyl-2,6-dimethyl-phenyl)-propionyl]-[1-(4-phenyl-1h-imidazol-2-yl)-ethyl]-amino}-methyl)-2-methoxy-benzoic acid.
    Type: Application
    Filed: July 7, 2008
    Publication date: January 15, 2009
    Inventors: Luigi Anzalone, Frank J. Villani, Christopher A. Teleha, Penina Feibush, Barry Fegely
  • Salt forms of substituted benzothienyl compounds
    Publication number: 20080097110
    Abstract: The present invention relates to novel salt forms of a compound of Formula (I): and processes for their preparation.
    Type: Application
    Filed: October 19, 2007
    Publication date: April 24, 2008
    Inventors: Luigi Anzalone, Frank Villani, Penina Feibush
  • Continuous process for the preparation of fructopyranose sulfamate derivatives
    Patent number: 7196209
    Abstract: The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) wherein R1, R3, R4, R5, R6 and X are as herein defined. The present invention is further directed to a continuous process for the preparation of Topiramate.
    Type: Grant
    Filed: October 23, 2003
    Date of Patent: March 27, 2007
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Thomas W. Adkins, Charles F. Cicco, Penina Feibush, Donald A. Koch, Cynthia Maryanoff, Walter E. Stalzer
  • Continuous process for the preparation of fructopyranose sulfamate derivatives
    Publication number: 20040158081
    Abstract: The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I) 1
    Type: Application
    Filed: October 23, 2003
    Publication date: August 12, 2004
    Inventors: Thomas W. Adkins, Charles F. Cicco, Penina Feibush, Donald A. Koch, Cynthia Maryanoff, Walter E. Stalzer