Patents by Inventor Penka Slavcheva Slavova-Petrova

Penka Slavcheva Slavova-Petrova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD47 blockade therapy by HDAC inhibitors
    Patent number: 11779631
    Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a histone deacetylase (HDAC) inhibitor. The anti-cancer effect of one drug enhances the anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of depsipeptide and romidepsin as HDAC inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: October 10, 2023
    Assignee: Pfizer Inc.
    Inventors: Emma Linderoth, Natasja Nielsen Viller, Robert Adam Uger, Penka Slavcheva Slavova-Petrova
  • ENHANCEMENT OF CD47 BLOCKADE THERAPY BY PROTEASOME INHIBITORS
    Publication number: 20230087443
    Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a proteasome inhibitor. The anti-cancer effect of one drug enhances the 5 anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of bortezomib, ixazomib and carfilzomib as proteasome inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
    Type: Application
    Filed: August 17, 2022
    Publication date: March 23, 2023
    Applicant: PF ARGENTUM IP HOLDINGS LLC
    Inventors: Emma Linderoth, Natasja Nielsen Viller, Robert Adam Uger, Penka Slavcheva Slavova-Petrova
  • Enhancement of CD47 blockade therapy by proteasome inhibitors
    Patent number: 11446315
    Abstract: CD47? disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a proteasome inhibitor. The anti-cancer effect of one drug enhances the 5 anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of bortezomib, ixazomib and carfilzomib as proteasome inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: September 20, 2022
    Assignee: PF Argentum IP Holdings LLC
    Inventors: Emma Linderoth, Natasja Nielsen Viller, Robert Adam Uger, Penka Slavcheva Slavova-Petrova
  • IMPROVEMENTS IN CD47 BLOCKADE THERAPY BY HDAC INHIBITORS
    Publication number: 20190269756
    Abstract: CD47+ disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a histone deacetylase (HDAC) inhibitor. The anti-cancer effect of one drug enhances the anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of depsipeptide and romidepsin as HDAC inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
    Type: Application
    Filed: November 1, 2017
    Publication date: September 5, 2019
    Applicant: TRILLIUM THERAPEUTICS INC.
    Inventors: Emma Linderoth, Natasja Nielsen Viller, Robert Adam Uger, Penka Slavcheva Slavova-Petrova
  • ENHANCEMENT OF CD47 BLOCKADE THERAPY BY PROTEASOME INHIBITORS
    Publication number: 20190255082
    Abstract: CD47? disease cells such as cancer cells are treated using a combination of CD47 blockade drug and a proteasome inhibitor. The anti-cancer effect of one drug enhances the 5 anti-cancer effect of the other. Specific combinations include SIRP?Fc as CD47 blockade drug, and one of bortezomib, ixazomib and carfilzomib as proteasome inhibitor. These combinations are useful particularly to treat blood cancers including lymphomas, leukemias and myelomas.
    Type: Application
    Filed: November 1, 2017
    Publication date: August 22, 2019
    Inventors: Emma Linderoth, Natasja Nielsen Viller, Robert Adam Uger, Penka Slavcheva Slavova-Petrova