Patents by Inventor Penny Joshi

Penny Joshi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metallation enhancements in tumor-imaging and PDT therapy
    Patent number: 9155791
    Abstract: A compound in the form of a metallized tetrapyrollic photosensitizer linked to a fluorescent dye where the photosensitizer (PS), is linked by a structure that does not have detrimental radiation emittance or absorbing characteristics, to a fluorophore, usually a cyanine dye (CD). The photosensitizer in accordance the invention is a metallized analog of porphyrins, chlorins, purpurinimides, bacterio pupurinimides, phthalocyanines, expanded porphyrins, benzoporphyrin derivatives and purpurins. The fluorophore is usually a cyanine dye with variable substituents. And, A method for determining effectiveness of PDT by comparing proportion of STAT-3 monomer with crosslinked STAT-3 dimer after PDT where the relative proportion of STAT-3 monomer to crosslinked STAT-3 directly correlates to efficacy of the PDT.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: October 13, 2015
    Assignee: Health Research, Inc.
    Inventors: Ravindra K. Pandey, Heinz Baumann, Yihui Chen, Penny Joshi, Nayan Patel
  • PAA nanoparticles for tumor treatment and imaging
    Patent number: 9045488
    Abstract: A tetrapyrrolic photosensitizer and imaging compound having a substituent other than hydrogen at its 10 carbon atom which substituent may contain a PAA nanoparticle.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: June 2, 2015
    Assignee: Photolitec, LLC
    Inventors: Ravindra K. Pandey, Anurag Gupta, Penny Joshi, Manivannan Ethirajan, Avinash Srivatsan
  • METALLATION ENHANCEMENTS IN TUMOR-IMAGING AND PDT THERAPY
    Publication number: 20140081015
    Abstract: A compound in the form of a metallized tetrapyrollic photosensitizer linked to a fluorescent dye where the photosensitizer (PS), is linked by a structure that does not have detrimental radiation emittance or absorbing characteristics, to a fluorophore, usually a cyanine dye (CD). The photosensitizer in accordance the invention is a metallized analog of porphyrins, chlorins, purpurinimides, bacterio pupurinimides, phthalocyanines, expanded porphyrins, benzoporphyrin derivatives and purpurins. The fluorophore is usually a cyanine dye with variable substituents. And, A method for determining effectiveness of PDT by comparing proportion of STAT-3 monomer with crosslinked STAT-3 dimer after PDT where the relative proportion of STAT-3 monomer to crosslinked STAT-3 directly correlates to efficacy of the PDT.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: Health Research, Inc.
    Inventors: Ravindra K. Pandey, Heinz Baumann, Yihui Chen, Penny Joshi, Nayan Patel
  • PAA NANOPARTICLES FOR TUMOR TREATMENT AND IMAGING
    Publication number: 20140011989
    Abstract: A tetrapyrrolic photosensitizer and imaging compound having a substituent other than hydrogen at its 10 carbon atom which substituent may contain a PAA nanoparticle.
    Type: Application
    Filed: July 9, 2012
    Publication date: January 9, 2014
    Applicant: PHOTOLITEC, LLC
    Inventors: Ravindra K. Pandey, Anurag Gupta, Penny Joshi, Manivannan Ethirajan, Avinash Srivatsan
  • Metallation enhancements in tumor-imaging and PDT therapy
    Patent number: 8609837
    Abstract: A compound in the form of a metallized tetrpyrollic photosensizer linked to a fluorescent dye where the photosensitizer (PS), is linked by a structure that does not have detrimental radiation emmitance or absorbing characteristics, to a fluorophore, usually a cyanine dye (CD). The photosensitizer in accordance the invention is a metallized analog of porphyrins, chlorins, purpurinimides, bacterio pupurinimides, phthalocyanines, expanded porphyrins, benzoporphyrin derivatives and purpurins. The fluorophore is usually a cyanine dye with variable substituents. And, A method for determining effectiveness of PDT by comparing proportion of STAT-3 monomer with crosslinked STAT-3 dimer after PDT where the relative proportion of STAT-3 monomer to crosslinked STAT-3 directly correlates to efficacy of the PDT.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: December 17, 2013
    Assignee: Health Research, Inc.
    Inventors: Ravindra K. Pandey, Heinz Baumann, Yihui Chen, Penny Joshi, Nayan Patel
  • METALLATION ENHANCEMENTS IN TUMOR-IMAGING AND PDT THERAPY
    Publication number: 20120097538
    Abstract: A compound in the form of a metallized tetrpyrollic photosensizer linked to a fluorescent dye where the photosensitizer (PS), is linked by a structure that does not have detrimental radiation emmitance or absorbing characteristics, to a fluorophore, usually a cyanine dye (CD). The photosensitizer in accordance the invention is a metallized analog of porphyrins, chlorins, purpurinimides, bacterio pupurinimides, phthalocyanines, expanded porphyrins, benzoporphyrin derivatives and purpurins. The fluorophore is usually a cyanine dye with varaible substituents. And, A method for determining effectiveness of PDT by comparing proportion of STAT-3 monomer with crosslinked STAT-3 dimer after PDT where the relative proportion of STAT-3 monomer to crosslinked STAT-3 directly correlates to efficacy of the PDT.
    Type: Application
    Filed: June 24, 2011
    Publication date: April 26, 2012
    Applicant: Health Research, Inc.
    Inventors: Ravindra K. Pandey, Heinz Baumann, Yihui Chen, Penny Joshi, Nayan Patel