Patents by Inventor Penrose Odonnell

Penrose Odonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR/Cas-related methods and compositions for improving transplantation
    Patent number: 11911415
    Abstract: Disclosed herein are compositions and methods for increasing the immunocompatibility of donor cells (e.g., HSCs or T-cells) for transplantation to a recipient subject, as well as database schemes for use in the methods. The methods and compositions described herein result in the allele-specific modification of one or more immunogenicity genes (e.g., an HLA gene) of a cell, resulting in cells that are suitable for transplantation into a recipient subject.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: February 27, 2024
    Assignee: Editas Medicine, Inc.
    Inventors: Jennifer Leah Gori, Tongyao Wang, Hariharan Jayaram, Penrose ODonnell
  • Crispr/Cas-Related Methods and Compositions for Treating Duchenne Muscular Dystrophy and Becker
    Publication number: 20190048337
    Abstract: CRISPR/CAS-related compositions and methods for treatment of DMD, BMD, or DCM type 3B are described.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 14, 2019
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Patrick David Hsu, Morgan Lee Maeder, Penrose Odonnell, Joshua C. Tycko, Nicholas C. Huston
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR IMPROVING TRANSPLANTATION
    Publication number: 20180296603
    Abstract: Disclosed herein are compositions and methods for increasing the immunocompatibility of donor cells (e.g., HSCs or T-cells) for transplantation to a recipient subject, as well as database schemes for use in the methods. The methods and compositions described herein result in the allele-specific modification of one or more immunogenicity genes (e.g., an HLA gene) of a cell, resulting in cells that are suitable for transplantation into a recipient subject.
    Type: Application
    Filed: June 9, 2016
    Publication date: October 18, 2018
    Inventors: Jennifer Leah Gori, Tongyao Wang, Hariharan Jayaram, Penrose ODonnell
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING HIV INFECTION AND AIDS
    Publication number: 20180119123
    Abstract: CRISPR/CAS-related systems, compositions and methods for editing CCR5 and/or CXCR4 genes in human cells are described, as are cells and compositions including cells edited according to the same.
    Type: Application
    Filed: November 10, 2017
    Publication date: May 3, 2018
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Jennifer Leah Gori, G. Grant Welstead, Penrose Odonnell