Patents by Inventor Per Bruheim

Per Bruheim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NRPS-PKS gene cluster and its manipulation and utility
    Patent number: 10047363
    Abstract: A nucleic acid molecule comprises a nucleotide sequence: as shown in SEQ ID No. 1, which is the complement of SEQ ID No. 1, which is degenerate with SEQ ID No. 1, or which has at least 85% sequence identity with SEQ ID No. 1, or which is a part of such a sequence. The nucleic acid molecule encodes or is a complementary to a nucleic acid molecule encoding one or more polypeptides, or comprises or is complementary to a nucleic acid molecule comprising one or more genetic elements, having functional activity in the synthesis of a polyketide-based or macrolactam molecule. The nucleic acid molecule may be used to prepare a modified BE-14106 biosynthetic gene cluster for the preparation of a modified BE-14106 molecule.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: August 14, 2018
    Assignee: SINTEF TTO AS
    Inventors: Hanne Jørgensen, Havard Sletta, Trond Erling Ellingsen, Espen Fjaervik, Kristin Fløgstad Degnes, Geir Klinkenberg, Per Bruheim, Sergey Zotchev
  • NRPS-PKS GENE CLUSTER AND ITS MANIPULATION AND UTILITY
    Publication number: 20160060636
    Abstract: A nucleic acid molecule comprises a nucleotide sequence: as shown in SEQ ID No. 1, which is the complement of SEQ ID No. 1, which is degenerate with SEQ ID No. 1, or which has at least 85% sequence identity with SEQ ID No. 1, or which is a part of such a sequence. The nucleic acid molecule encodes or is a complementary to a nucleic acid molecule encoding one or more polypeptides, or comprises or is complementary to a nucleic acid molecule comprising one or more genetic elements, having functional activity in the synthesis of a polyketide-based or macrolactam molecule. The nucleic acid molecule may be used to prepare a modified BE-14106 biosynthetic gene cluster for the preparation of a modified BE-14106 molecule.
    Type: Application
    Filed: November 11, 2015
    Publication date: March 3, 2016
    Inventors: Hanne JØRGENSEN, Havard SLETTA, Trond Erling ELLINGSEN, Espen FJAERVIK, Kristin Fløgstad DEGNES, Geir KLINKENBERG, Per BRUHEIM, Sergey ZOTCHEV
  • NRPS-PKS gene cluster and its manipulation and utility
    Patent number: 9217150
    Abstract: The present invention provides a nucleic acid molecule comprising: (a) a nucleotide sequence as shown in SEQ ID No. 1; or (b) a nucleotide sequence which is the complement of SEQ ID No. 1; or (c) a nucleotide sequence which is degenerate with SEQ ID No. 1; or (d) a nucleotide sequence having at least 85% sequence identity (preferably at least 87%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% sequence identity) with SEQ ID No. 1; or (e) a part of any one of (a) to (d), wherein said nucleic acid molecule encodes or is a complementary to a nucleic acid molecule encoding one or more polypeptides, or comprises or is complementary to a nucleic acid molecule comprising one or more genetic elements, having functional activity in the synthesis of a polyketide-based or macrolactam molecule.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: December 22, 2015
    Assignee: SINTEF TTO AS
    Inventors: Hanne Jørgensen, Trond Erling Ellingsen, Kristin Fløgstad Degnes, Per Bruheim, Håvard Sletta, Espen Fjærvik, Geir Klinkenberg, Sergey Zotchev
  • METHODS AND STRAINS FOR THE PRODUCTION OF SARCINAXANTHIN AND DERIVATIVES THEREOF
    Publication number: 20130130312
    Abstract: The present invention relates to a new strain of Micrococcus luteus, named Otnes7, which is superior to known strains in its ability to synthesise the carotenoid sarcinaxanthin and a method of producing sarcinaxanthin or a derivative thereof, said method comprising introducing into and expressing in a host cell one or more nucleic acid molecules encoding an activity in the sarcinaxanthin biosynthetic pathway.
    Type: Application
    Filed: June 1, 2011
    Publication date: May 23, 2013
    Applicant: Promar AS
    Inventors: Roman Netzer, Trygve Brautaset, Per Bruheim
  • NRPS-PKS Gene Cluster and its Manipulation and Utility
    Publication number: 20110117606
    Abstract: The present invention provides a nucleic acid molecule comprising: (a) a nucleotide sequence as shown in SEQ ID No. 1; or (b) a nucleotide sequence which is the complement of SEQ ID No. 1; or (c) a nucleotide sequence which is degenerate with SEQ ID No. 1; or (d) a nucleotide sequence having at least 85% sequence identity (preferably at least 87%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% sequence identity) with SEQ ID No. 1; or (e) a part of any one of (a) to (d), wherein said nucleic acid molecule encodes or is a complementary to a nucleic acid molecule encoding one or more polypeptides, or comprises or is complementary to a nucleic acid molecule comprising one or more genetic elements, having functional activity in the synthesis of a polyketide-based or macrolactam molecule.
    Type: Application
    Filed: March 20, 2009
    Publication date: May 19, 2011
    Inventors: Hanne Jørgensen, Trond Erling Ellingsen, Kristin Fløgstad Degnes, Per Bruheim, Håvard Sletta, Espen Fjaervik, Geir Klinkenberg, Sergey Zotchev