Abstract: The present invention relates to a computer implemented method performed by a device (600) configured to synthesize molecules, wherein the synthesizing comprises performing cycles of a plurality of process steps (PS1-PS4), wherein the synthesizing is controlled by blocks of parameters, the method comprising receiving an indication of a target molecule, generating a synthesizing process description (300) by generating a plurality of blocks (310) of parameters, each block (310) controlling process steps of a respective cycle, receiving user input indicative of modification of the generated plurality of blocks of parameters, modifying the generated plurality of blocks of parameters using the user input, controlling synthesizing of the target molecule by applying the modified plurality of blocks of parameters to control of the respective cycles.

Abstract: The invention relates to processes for purification of poly-tagged products, such as mRNA, from synthetic or biological compositions. The process involves contacting the composition with a oligo d (T)-functionalized chromatography medium comprising a convection-based chromatography material.

Abstract: An arrangement for a column comprising a stand provided with a platform adapted to receive a second end of a tubular housing and for supporting the arrangement on a floor, a first end unit removably connected to a first end of the tubular housing, an adaptor assembly movable within said tubular housing and an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit. A frame is connected to the first end unit, which frame and first end unit can be lifted and lowered in a substantially vertical direction, so that the tubular housing may be removed and substituted for another tubular housing with different dimensions in relation to the removed tubular housing when the frame and first end unit are lifted.

Abstract: An arrangement for a column comprising a stand provided with a platform adapted to receive a second end of a tubular housing and for supporting the arrangement on a floor, a first end unit removably connected to a first end of the tubular housing, an adaptor assembly movable within said tubular housing and an adaptor rod connected to said adaptor assembly, which adaptor rod is arranged to extend through an opening in the first end unit. A frame is connected to the first end unit, which frame and first end unit can be lifted and lowered in a substantially vertical direction, so that the tubular housing may be removed and substituted for another tubular housing with different dimensions in relation to the removed tubular housing when the frame and first end unit are lifted.