Patents by Inventor Per EDEBRINK

Per EDEBRINK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMBINATION OF TIS SEQUENCE AND SIGNAL PEPTIDE SEQUENCE FOR EXPRESSING A RECOMBINANT PROTEIN
    Publication number: 20230175008
    Abstract: The present invention relates to DNA constructs comprising a novel TIS sequence. The TIS sequence transcribes into an RNA motif that functions as the protein translation initiation site in an mRNA transcript. The DNA construct may further comprise a nucleic acid sequence encoding signal peptide. Additionally, the DNA constructs may also comprise a nucleic acid sequence encoding a recombinant protein or one or more polypeptide chains thereof. The invention further relates to an expression vector, expression cassette and host cell which comprise said DNA constructs. Furthermore, the present invention relates to a recombinant protein expressed by the host cell as well as a method for expressing the recombinant protein.
    Type: Application
    Filed: March 17, 2021
    Publication date: June 8, 2023
    Applicant: XBRANE BIOPHARMA AB
    Inventors: Kiavash MIRZADEH, Veronica RAMBERG, Nathalie CHATZISSAVIDOU, Patrik SAMUELSON, Siavash BASHIRI, Per EDEBRINK, Joanne STEVENSON, David VIKSTROM