Patents by Inventor Per Kaersgaard

Per Kaersgaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE PURIFICATION OF PROTEINS USING CAPRYLIC ACID
    Publication number: 20220324906
    Abstract: A protein purification process with virus inactivation or removal uses caprylic acid (octanoic acid) at acidic pH. The method comprises caprylic acid treatment as part of the chromatographic step so as to perform viral inactivation without a discontinuous process and without the requirement of attention by personnel, particularly when the pH adjustment of the eluate is performed automatically by eluting into buffer. The method of the invention further results in mycoplasmas being inactivated, and reduced impurities like Host Cell Protein (HCP).
    Type: Application
    Filed: June 6, 2022
    Publication date: October 13, 2022
    Inventors: Ole Elvang Jensen, Per Kaersgaard
  • METHODS FOR THE PURIFICATION OF PROTEINS USING CAPRYLIC ACID
    Publication number: 20170044210
    Abstract: A protein purification process with virus inactivation or removal uses caprylic acid (octanoic acid) at acidic pH. The method comprises caprylic acid treatment as part of the chromatographic step so as to perform viral inactivation without a discontinuous process and without the requirement of attention by personnel, particularly when the pH adjustment of the eluate is performed automatically by eluting into buffer. The method of the invention further results in mycoplasmas being inactivated, and reduced impurities like Host Cell Protein (HCP).
    Type: Application
    Filed: April 30, 2015
    Publication date: February 16, 2017
    Inventors: Ole Elvang Jensen, Per Kaersgaard
  • Closed container comprising an activated factor VII polypeptide, processes for the preparation of the same, and a kit and a method for use of the kit
    Patent number: 8703706
    Abstract: The present invention relates to a closed container holding a composition of an activated Factor VII polypeptide in an amount of in the range of 2.5-90 mg per imL volume of the container. The invention also relates to various processes for the preparation of such closed containers, a kit including such containers and a method of using the kit.
    Type: Grant
    Filed: April 28, 2006
    Date of Patent: April 22, 2014
    Assignee: Novo Nordisk Healthcare AG
    Inventors: Anne Charlotte Arentsen, Per Kaersgaard
  • Closed Container Comprising an Activated Factor VII Polypeptide, Processes for the Preparation of the Same, and a Kit and a Method for Use of the Kit
    Publication number: 20080206225
    Abstract: The present invention relates to a closed container holding a composition of an activated Factor VII polypeptide in an amount of in the range of 2.5-90 mg per imL volume of the container. The invention also relates to various processes for the preparation of such closed containers, a kit including such containers and a method of using the kit.
    Type: Application
    Filed: April 28, 2006
    Publication date: August 28, 2008
    Applicant: Novo Nordisk Health Care A/G
    Inventors: Anne Charlotte Arentsen, Per Kaersgaard
  • von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
    Patent number: 6531577
    Abstract: A high-purity von Willebrand factor preparation, a process for making it, and use of the preparation and compositions containing it for the treatment of disorders are disclosed.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: March 11, 2003
    Assignee: Hemasure Denmark A/S
    Inventors: Per Kaersgaard, Karina Alsoe Barington
  • Method for isolating factors VIII from plasma by gel filtration chromatography under group separation conditions
    Patent number: 5245014
    Abstract: A method for isolating Factor VIII from other proteins dissolved in blood plasma is disclosed, wherein plasma is subjected to gel filtration under group separation conditions giving a fraction containing Factor VIII in very high yield and almost free of other proteins.
    Type: Grant
    Filed: November 7, 1990
    Date of Patent: September 14, 1993
    Assignee: Novo Nordisk A/S
    Inventor: Per Kaersgaard