Patents by Inventor Per Lennart Lindfors

Per Lennart Lindfors has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of crystalline nano-particle dispersions
    Patent number: 7780989
    Abstract: A process for the preparation of a dispersion of crystalline nanoparticles in an aqueous medium is disclosed. Specifically, a first solution comprising a substantially water-insoluble substance in a water-miscible organic solvent is rapid mixed with an aqueous phase comprising water, and optionally a stabilizer, to form a dispersion of amorphous particles. The dispersion of amorphous particles is then sonicated for a sufficient period to form crystalline nanoparticles of the substantially water-insoluble substance. The process provides nanocrystals with a mean hydrodynamic diameter of less than 1 micron, particularly less than 300 nm, and is particularly useful for the preparation of nanocrystalline dispersions of pharmaceutical substances.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: August 24, 2010
    Assignee: AstraZeneca AB
    Inventors: Tommy Urban Skantze, Per Lennart Lindfors, Sara Forssen