Patents by Inventor Per Marin

Per Marin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating diabetes, metabolic syndrome and other conditions
    Patent number: 11478471
    Abstract: Pharmaceuticals compositions comprising the 2S,4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R,4S ketoconazole enantiomer are useful to reduce cortisol synthesis and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: October 25, 2022
    Assignee: Strongbridge Dublin Limited
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20210299122
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: November 10, 2020
    Publication date: September 30, 2021
    Inventor: Per Marin
  • Methods and compositions for treating diabetes, metabolic syndrome and other conditions
    Patent number: 10835530
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: November 17, 2020
    Assignee: Strongbridge Dublin Limited
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20200261446
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: December 16, 2019
    Publication date: August 20, 2020
    Inventor: Per Marin
  • Methods and compositions for treating diabetes, metabolic syndrome and other conditions
    Patent number: 10517868
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: December 31, 2019
    Assignee: Strongbridge Dublin Limited
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20190070175
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: October 4, 2018
    Publication date: March 7, 2019
    Inventor: Per Marin
  • Methods and compositions for treating diabetes, metabolic syndrome and other conditions
    Patent number: 10098877
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: October 16, 2018
    Assignee: Strongbridge Ireland Limited
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20180153883
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventor: Per Marin
  • Methods and compositions for treating diabetes, metabolic syndrome and other conditions
    Patent number: 9918984
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: March 20, 2018
    Assignee: CORTENDO AB (PUBL)
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20160243115
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: April 1, 2016
    Publication date: August 25, 2016
    Inventor: Per Marin
  • Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor
    Patent number: 7960410
    Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.
    Type: Grant
    Filed: September 10, 2005
    Date of Patent: June 14, 2011
    Assignee: Cortendo AB
    Inventor: Per Marin
  • Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor
    Patent number: 7872008
    Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: January 18, 2011
    Assignee: Cortendo AB
    Inventor: Per Marin
  • METHODS AND COMPOSITIONS FOR TREATING DIABETES, METABOLIC SYNDROME AND OTHER CONDITIONS
    Publication number: 20090233843
    Abstract: Pharmaceuticals compositions comprising the 2S, 4R, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2R, 4S ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, Metabolic Syndrome, and other diseases and conditions, including but not limited to Cushing's Syndrome, depression, and glaucoma.
    Type: Application
    Filed: January 10, 2006
    Publication date: September 17, 2009
    Applicant: Cortendo Invest AB
    Inventor: Per Marin
  • Method for determining whether condition is symptom of metabolic syndrome
    Patent number: 7217505
    Abstract: The use of cortisol agonist for preparing a system for diagnosis of the metabolic syndrome and related conditions as belly fatness, insulin resistancy including increased risk of developing senile diabetes, i.e. diabetes type II, high blood fats and high blood pressure, in which system the dose of cortisol agonist is in an interval where a difference is obtained in the inhibitory effect of the autoproduction of cortisol in individuals suffering from the metabolic syndrome, compared to normal values.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: May 15, 2007
    Assignee: Cortendo AB
    Inventor: Per Marin
  • Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor
    Publication number: 20060014758
    Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.
    Type: Application
    Filed: September 10, 2005
    Publication date: January 19, 2006
    Inventor: Per Marin
  • Use of cortisol antagonists in the treatment of heart failure
    Patent number: 6881739
    Abstract: The present invention relates to the use of a cortisol antagonist in the manufacture of a medicament for the treatment of heart failure as well as to a method of treating heart failure which comprises administration of a cortisol antagonist and to a product containing (a) a cortisol antagonist and (b) a second drug as a combined preparation for simultaneous, separate or sequential use in the treatment of heart failure or in improving cardiac function and reducing exercise intolerance.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: April 19, 2005
    Inventors: Per Marin, Sten Sorensen
  • Method for treating a patient having metabolic syndrome
    Patent number: 6846800
    Abstract: Methods for treating a patient for insulin resistance to decrease the insulin resistance in a patient having Metabolic Syndrome comprising Primary Insulin Resistance and abdominal/visceral obesity comprise administering to the patient growth hormone or a functional derivative thereof in an amount effective for decreasing insulin resistance of the patient.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: January 25, 2005
    Assignee: Pharmacia AB
    Inventors: Gudmundur Johannsson, Per Mårin, Lars Lönn, Malin Ottosson, Kaj Stenlöf, Per Björntorp, Lars Sjöström, Bengt-Åke Bengtsson
  • Use of growth hormone
    Publication number: 20040180833
    Abstract: A method for treating a patient having Metabolic Syndrome comprising Primary Insulin Resistance and exhibiting lipoprotein aberrations or hypertension comprises administering to said patient human growth hormone or a functional analog thereof in an amount effective for decreasing lipoprotein aberrations or hypertension of said patient.
    Type: Application
    Filed: March 25, 2004
    Publication date: September 16, 2004
    Inventors: Gudmundur Johannsson, Per Marin, Lars Lonn, Malin Ottosson, Kaj Stenlof, Per Bjorntorp, Lars Sjostrom, Bengt-Ake Bengtsson
  • Method for treating insulin resistance, abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids with a cortisol inhibitor
    Publication number: 20040077660
    Abstract: The invention concerns the use of ketoconazole and derivatives having a corresponding biological activity, and combinations thereof, in the treatment of abdominal obesity, hypertension, hyperinsulinemia, and elevated blood lipids.
    Type: Application
    Filed: September 4, 2003
    Publication date: April 22, 2004
    Inventor: Per Marin
  • Methods for prophylactic treatment of cardiovascular disease with inhibitor of cortisol synthesis
    Patent number: 6642236
    Abstract: Ketoconazole and related substances which are inhibitors of cortisol synthesis can be administered to prophylactically treat cardiovascular disease, such as coronary artery disease, artiosclerotic manifestations, and stroke.
    Type: Grant
    Filed: November 14, 2000
    Date of Patent: November 4, 2003
    Assignee: Cortendo AB
    Inventor: Per Märin