Patents by Inventor Per Otto Hagen

Per Otto Hagen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioengineered vascular graft support prostheses
    Patent number: 7041131
    Abstract: The invention is directed to bioengineered vascular graft support prostheses prepared from cleaned tissue material derived from animal sources. The bioengineered graft prostheses of the invention are prepared using methods that preserve cell compatibility, strength, and bioremodelability of the processed tissue matrix. The bioengineered graft prostheses are used for implantation, repair, or for use in a mammalian host.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: May 9, 2006
    Assignee: Organogenesis, Inc.
    Inventors: Ginger A. Abraham, Robert M. Carr, Jr., Tam Huynh, Per Otto Hagen, Mark Davies
  • Method of inhibiting smooth muscle cell proliferation
    Patent number: 6683057
    Abstract: The present invention relates, in general, to vascular smooth muscle proliferation and, in particular, to a method of inhibiting arterial and venous smooth muscle proliferation resulting, for example, from arterial injury or vein grafting. The invention also relates to an expression construct encoding a G&bgr;&ggr; inhibitor suitable for use in such a method.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: January 27, 2004
    Assignee: Duke University
    Inventors: Walter J. Koch, Robert J. Lefkowitz, Per-Otto Hagen
  • Bioengineered vascular graft support prostheses
    Publication number: 20030195618
    Abstract: The invention is directed to bioengineered vascular graft support prostheses prepared from cleaned tissue material derived from animal sources. The bioengineered graft prostheses of the invention are prepared using methods that preserve cell compatibility, strength, and bioremodelability of the processed tissue matrix. The bioengineered graft prostheses are used for implantation, repair, or for use in a mammalian host.
    Type: Application
    Filed: April 11, 2003
    Publication date: October 16, 2003
    Applicants: Organogenesis, Inc., Duke University School of Medicine
    Inventors: Ginger A. Abraham, Robert M. Carr, Tam Huynh, Per Otto Hagen, Mark Davies
  • Method of inhibiting smooth muscle cell proliferation
    Patent number: 5981487
    Abstract: The present invention relates, in general, to vascular smooth muscle proliferation and, in particular, to a method of inhibiting arterial and venous smooth muscle proliferation resulting, for example, from arterial injury or vein grafting. The invention also relates to an expression construct encoding a G.beta..gamma. inhibitor suitable for use in such a method.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: November 9, 1999
    Assignee: Duke University
    Inventors: Walter J. Koch, Robert J. Lefkowitz, Per-Otto Hagen