Patents by Inventor Per Sauerberg

Per Sauerberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
    Publication number: 20010031762
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: April 13, 2001
    Publication date: October 18, 2001
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • New compounds, their preparation and use
    Publication number: 20010029256
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: March 14, 2001
    Publication date: October 11, 2001
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6300339
    Abstract: The present invention relates to compounds of formula (I) wherein A, B, Q, T, X, Y, Z, R5, R6, R7, R8, Ar, k, m, n and p are as defined in the specification. These compounds are useful in treating or preventing conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: October 9, 2001
    Assignees: Novo Nordisk A/S, Dr. Reddy's Research Foundation
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Method for treating schizophrenia
    Patent number: 6284771
    Abstract: The present invention provides a method for treating a condition selected from the group consisting of schizophrenia, schizoaffective disorder, and schizophreniform disorder in a patient using a Compound (I).
    Type: Grant
    Filed: April 3, 2000
    Date of Patent: September 4, 2001
    Assignee: Eli Lilly and Company
    Inventors: Charles H. Mitch, Per Sauerberg, Harlan E. Shannon
  • Compounds, their preparation and use
    Patent number: 6274608
    Abstract: Disclosed are novel compounds of formula I wherein R1, R2, R3, L, X and Y are as defined in the specification. These compounds are useful in the treatment of conditions mediated by nuclear receptors, in particular the Retinoid X Receptor (RXR) and the Peroxisome Proliferator-Activated Receptor (PPAR) families. Such conditions include diabetes and obesity.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: August 14, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Anthony Murray, Lone Jeppesen, Paul Stanley Bury, Ingrid Pettersson
  • Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
    Patent number: 6248781
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, Ar, X, Q, A, Y and Z are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: June 19, 2001
    Assignees: Novo Nordisk A/S, Dr. Reddy's Research Foundation
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6214820
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, A, X, T, Q, Z, U, Y, Ar, p and n are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: April 10, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Heterocyclic compounds and their preparation and use
    Patent number: 6083957
    Abstract: The present invention relates to therapeutically active quaternary azacyclic or azabicyclic compounds with formula I: ##STR1## wherein X is oxygen or sulfur and wherein G is selected from the group of azacyclic or azabicyclic ring systems consisting of: ##STR2## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a cholinergic deficit in the peripheral system.
    Type: Grant
    Filed: April 17, 1997
    Date of Patent: July 4, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Preben H. Olesen, Per Sauerberg
  • Heterocyclic compounds and their preparation and use
    Patent number: 6015813
    Abstract: The present invention relates to therapeutically active azabicyclic compounds of formula I ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, Ar, m and n are defined in the description, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a disease in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
    Type: Grant
    Filed: April 8, 1998
    Date of Patent: January 18, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Lone Jeppesen, Per Sauerberg
  • Azacyclic and azabicyclic substituted oxa- or thia-diazole compounds
    Patent number: 5977129
    Abstract: The present invention relates to compounds of formula I: whereinone or both G is an azacyclic ring of formula II: ##STR1## and Z is oxygen or sulfur and the remaining variables are as defined in the specification. The compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: November 2, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Preben H. Olesen, Per Sauerberg
  • Antipsychotic method
    Patent number: 5968926
    Abstract: The present invention relates to a novel method for treating a mammal suffering from or susceptible to schizophrenia and schizophreniform diseases.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 19, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Franklin Porter Bymaster, Harlan E. Shannon, Per Sauerberg, Preben Olesen, John Stanley Ward, Charles H. Mitch
  • Hetrocyclic compounds and their preparation and use
    Patent number: 5919805
    Abstract: The present invention relates to therapeutically active azacyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: July 6, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Preben H. Olesen, Charles H. Mitch
  • Heterocyclic compounds and their preparation and use
    Patent number: 5914338
    Abstract: The present invention relates to therapeutically active azatricyclic compounds of formula I ##STR1## a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating a disease in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
    Type: Grant
    Filed: April 1, 1997
    Date of Patent: June 22, 1999
    Assignee: Novo Nordisk
    Inventors: Lone Jeppesen, Preben H. Olesen, Per Sauerberg
  • Heterocyclic compounds and their use
    Patent number: 5773452
    Abstract: The present invention relates to therapeutically active azabicyclic compounds of formula (1), wherein Z1 is oxygen or sulphur, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: October 31, 1995
    Date of Patent: June 30, 1998
    Assignee: Novo Nordisk Als
    Inventors: Per Sauerberg, Preben H. Olesen, Charles H. Mitch
  • Method of treating hypercholesterolemia and related disorders
    Patent number: 5750538
    Abstract: The present invention relates to a novel method for treating a mammal suffering from hypercholesterolemia and related disorders.
    Type: Grant
    Filed: January 3, 1997
    Date of Patent: May 12, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Kristian Tage Hansen
  • Heterocyclic compounds and their preparation and use
    Patent number: 5741788
    Abstract: The present invention relates to therapeutically active azacyclic or azabicyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful in treating diseases in the central nervous system caused by malfunctioning of the muscarinic cholinergic system.
    Type: Grant
    Filed: November 17, 1995
    Date of Patent: April 21, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Preben H. Olesen, Per Sauerberg
  • Piperdine compounds and their preparation and use
    Patent number: 5712297
    Abstract: The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: September 23, 1996
    Date of Patent: January 27, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Preben H. Olesen
  • Antipsychotic method
    Patent number: 5679686
    Abstract: The present invention relates to a novel method for treating a mammal suffering from or susceptible to schizophrenia and schizophreniform diseases.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: October 21, 1997
    Assignee: Novo Nordisk A/S
    Inventors: Franklin Porter Bymaster, Harlan E. Shannon, Per Sauerberg, Preben H. Olesen, John Stanley Ward, Charles H. Mitch
  • Heterocyclic compounds
    Patent number: RE35822
    Abstract: The present invention relates to therapeutically active azacyclic compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: June 9, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Prebert H. Olesen, Charles H. Mitch
  • Treatment of Alzheimer's disease using azacyclic compounds
    Patent number: RE36375
    Abstract: The present invention relates to therapeutically active azacyclic compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
    Type: Grant
    Filed: February 18, 1998
    Date of Patent: November 2, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Preben H. Olesen, Charles H. Mitch