Patents by Inventor Per Uselius

Per Uselius has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180229152
    Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.
    Type: Application
    Filed: April 16, 2018
    Publication date: August 16, 2018
    Applicant: GE Healthcare BioProcess R&D AB
    Inventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Patent number: 9943781
    Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: April 17, 2018
    Assignee: GE HEALTHCARE BIOPROCESS R&D AB
    Inventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Patent number: 9155979
    Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: October 13, 2015
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Patent number: 8778188
    Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.
    Type: Grant
    Filed: October 14, 2008
    Date of Patent: July 15, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
  • Publication number: 20140131267
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Application
    Filed: January 21, 2014
    Publication date: May 15, 2014
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
  • Publication number: 20140131266
    Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).
    Type: Application
    Filed: January 20, 2014
    Publication date: May 15, 2014
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: MANOJ KUMAR RAMAKRISHNA, DANIEL SALOMONSSON, PER USELIUS
  • Patent number: 8668829
    Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: March 11, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Patent number: 8663477
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: March 4, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Per Uselius, Kyril Dambuleff, John Davis
  • Publication number: 20130341482
    Abstract: A method for conducting maintenance on a chromatography column (1; 51), said column comprising a column tube (32), a top end cell (20) and a bottom end cell (26), where during chromatography said column tube (32) is secured between said top end cell (20) and said bottom end cell (26). Said method comprises the step of rotating at least the top end cell (20) 180 degrees around a horizontal axis before maintenance is conducted to the top end cell (20).
    Type: Application
    Filed: June 21, 2012
    Publication date: December 26, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: PER USELIUS, KYRIL DAMBULEFF, JOHN DAVIS
  • Patent number: 8585894
    Abstract: A nozzle assembly (1) provided in a chromatography column (3), said nozzle assembly comprising a nozzle tube (21) through which chromatography media slurry is to be provided to the column (3). According to the invention said nozzle assembly (1) further comprises a pivot (39) connected in a first end (40a) to a pivot point arm (35), said pivot (39) can be pivoted into at least two different locked pivot positions and said pivot (39) being connected to the nozzle tube (21) such that a nozzle tip (25) of said nozzle tube is adjusted into at least two different locked nozzle tip positions corresponding to the at least two different locked pivot positions.
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: November 19, 2013
    Assignee: GE Healthcare Bio-Sciences AB
    Inventor: Per Uselius
  • Patent number: 8562827
    Abstract: In a chromatography column, at least one plastic retaining mesh is attached to a distributor plate using a fixture element comprising an elongated edge that penetrates into the plastic mesh to ensure sealing and to prevent radial movement of the plastic mesh.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: October 22, 2013
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Daniel Salomonsson, Petter Bennemo, Per Uselius
  • Publication number: 20130087491
    Abstract: A method for performing maintenance on a chromatography column (1; 41) comprising the steps of: a) when maintenance is required, detaching a detachable joint (7; 63) between a bottom plate (5; 53) of the chromatography column and a stand (3; 43) on which the chromatography column is provided; b) attaching an adaptor (15; 59) provided in the chromatography system to any part of the chromatography column (1; 41) making it possible to lift the bottom plate (5; 53) from the stand (3; 43) with the adaptor (15; 59); and c) raising the adaptor (15; 59) and thereby also the bottom plate (5; 53) such that maintenance can be performed under the bottom plate (5; 53).
    Type: Application
    Filed: June 16, 2011
    Publication date: April 11, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Publication number: 20130068671
    Abstract: A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b) connected in a rigid housing (21; 61), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules in the rigid housing are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.
    Type: Application
    Filed: June 1, 2011
    Publication date: March 21, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Klaus Gebauer, Manoj Kumar Ramakrishna, Daniel Salomonsson, Per Uselius
  • Publication number: 20130001147
    Abstract: In a chromatography column, at least one plastic retaining mesh is attached to a distributor plate using a fixture element comprising an elongated edge that penetrates into the plastic mesh to ensure sealing and to prevent radial movement of the plastic mesh.
    Type: Application
    Filed: March 10, 2011
    Publication date: January 3, 2013
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Daniel Salomonsson, Petter Bennemo, Per Uselius
  • Publication number: 20090039023
    Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.
    Type: Application
    Filed: October 14, 2008
    Publication date: February 12, 2009
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: PER USELIUS, Mats Olsson, Sven Woulder, Jerker Persson
  • Patent number: 7452464
    Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: November 18, 2008
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
  • Publication number: 20060091052
    Abstract: A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column wall, a second end plate assembly removably connectable to said second end of the column wall, wherein said first end plate assembly, said column wall and said second end plate assembly are arranged along the longitudinal axis of the column wherein the column wall, and/or first end plate assembly and/or second end plate assembly is/are rotatable about an axis of rotation wherein said axis of rotation is parallel to the longitudinal axis of said column and positioned outside the column.
    Type: Application
    Filed: July 18, 2005
    Publication date: May 4, 2006
    Inventors: Per Uselius, Mats Olsson, Sven Wounder, Jerker Persson
  • Patent number: D715957
    Type: Grant
    Filed: November 21, 2012
    Date of Patent: October 21, 2014
    Assignee: GE Healthcare Bio-Sciences AB
    Inventor: Per Uselius