Patents by Inventor Per Vedso

Per Vedso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urea Glucokinase Activators
    Publication number: 20090105482
    Abstract: The invention provides a compound of general formula (I) wherein the substituents are defined further in the application, as well as further embodiments hereof described in the attached embodiments. The present invention also provides use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes.
    Type: Application
    Filed: July 14, 2006
    Publication date: April 23, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Jesper Lau, Anthony Murray, Per Vedso, Marit Kristiansen, Lone Jeppesen
  • Dicycloalkylcarbamoyl Ureas As Glucokinase Activators
    Publication number: 20080319028
    Abstract: This invention relates to dicycloalkylcarbamoyl ureas of formula (I), which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: July 7, 2006
    Publication date: December 25, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Per Vedso, Lone Jeppesen, Marit Kristiansen
  • Aryl carbonyl derivatives as therapeutic agents
    Patent number: 7384967
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: June 10, 2008
    Assignee: Novo Nordisk A/S
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper Lau, Paw Bloch, Mustafa Guzel, Kalpathy Chidambareswaran Santhosh, Adnan M. M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20080119455
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20080119454
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 22, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
    Patent number: 7279470
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: October 9, 2007
    Assignee: Novo Nordisk A/S
    Inventors: Soren Ebdrup, Johannes Cornelis de Jong, Poul Jacobsen, Holger Claus Hansen, Per Vedso
  • Heteroaryl-ureas and their use as glucokinase activators
    Publication number: 20070054897
    Abstract: This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: June 14, 2006
    Publication date: March 8, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Lone Jeppesen, Per Vedso, Michael Ankersen, Jane Lundbeck, Marit Kristiansen, Maria Valcarce-Lopez, Dharma Polisetti, Govindan Subramanian, Robert Andrews, Daniel Christen, Jeremy Cooper, Kalpathy Santhosh
  • N-heteroaryl indole carboxamides and analogues thereof, for use as glcokinase activators in the treatment of diabetes
    Publication number: 20070027140
    Abstract: This invention relates to compounds that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial. The compounds are of the general formula (I) wherin A and B are further defined in the application.
    Type: Application
    Filed: May 24, 2006
    Publication date: February 1, 2007
    Applicant: Novo Nordisk A/S
    Inventors: Jesper Lau, Per Vedso, Janos Kodra, Anthony Murray, Lone Jeppesen, Michael Ankersen, Govindan Subramanian, Adnan Mjalli, Robert Andrews, Dharma Pollisetti, Daniel Christen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20060183783
    Abstract: This invention relates to aryl carbonyl derivativeswhich are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: March 1, 2006
    Publication date: August 17, 2006
    Inventors: Dharma Polisetti, Janos Kodra, Jesper Lau, Paw Bloch, Maria Lopez, Niels Blume, Mustafa Guzel, Kalpathy Santhosh, Adnan Mjalli, Robert Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Substituted piperazine carbamates
    Publication number: 20060160820
    Abstract: Novel substituted piperazine carbamates, pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to hormone sensitive lipase. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which modulation of the activity of hormone sensitive lipase is beneficial.
    Type: Application
    Filed: December 12, 2005
    Publication date: July 20, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Holger Hansen, Johannes de Jong, Poul Jacobsen, Soren Ebdrup, Per Vedso
  • Substituted piperidine carbamates
    Publication number: 20060160851
    Abstract: Novel substituted piperidine carbamates, pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to hormone sensitive lipase. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which modulation of the activity of hormone sensitive lipase is beneficial.
    Type: Application
    Filed: December 12, 2005
    Publication date: July 20, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Soren Ebdrup, Per Vedso, Poul Jacobsen, Flemming Nielsen, Johannes Cornelis de Jong
  • Substituted p-phenyl carbamates
    Publication number: 20060148860
    Abstract: Novel substituted p-phenyl carbamates, pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to hormone sensitive lipase. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which modulation of the activity of hormone sensitive lipase is beneficial.
    Type: Application
    Filed: December 12, 2005
    Publication date: July 6, 2006
    Applicant: Novo Nordisk A/S
    Inventors: Per Vedso, Soren Ebdrup, Poul Jacobsen
  • Use of compounds for decreasing activity of hormone-sensitive lipase
    Patent number: 7067517
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Grant
    Filed: December 13, 2002
    Date of Patent: June 27, 2006
    Assignee: Nero Nordisk A/S
    Inventors: Soren Ebdrup, Johannes Cornelis de Jong, Poul Jacobsen, Holger Claus Hansen, Per Vedso
  • Pharmaceutical use of boronic acids and esters thereof
    Patent number: 7037905
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, method of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of a range of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: May 2, 2006
    Assignee: Novo Nordisk A/S
    Inventors: Soren Ebdrup, Per Vedso, Poul Jacobsen
  • Halo sulfonyl aryl boronates
    Patent number: 6872849
    Abstract: The present invention relates to halo sulfonyl aryl boronates of the general formula (I): wherein Arylene designates a carbocyclic or heterocyclic, aromatic ring system comprising 1-3 rings; R1, R2 and R3 are, independently, hydrogen, C1-6alkyl, C1-6alkoxy, halogen, nitro, cyano or phenyl; X is fluoro, chloro or bromo; and Y is a boroxine moiety attached via a bond from Arylene to one of the boron atoms of a boroxine ring which ring has a group of the formula -Arylene(R1)(R2)(R3)SO2X, wherein Arylene, R1, R2, R3 and X are as defined above, at each of the other two boron atoms of the boroxine ring, or Y is a boronic acid group or a boronic ester group. The invention also relates to the preparation of the compounds of formula (I) and to their use in organic synthesis.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: March 29, 2005
    Assignee: Novo Nordisk A/S
    Inventors: Per Vedso, Preben Houlberg Olesen, Thomas Hoeg-Jensen
  • Aryl carbonyl derivatives as therapeutic agents
    Publication number: 20040122235
    Abstract: This invention relates to aryl carbonyl derivatives which are activators of glucokinase which may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Application
    Filed: October 6, 2003
    Publication date: June 24, 2004
    Inventors: Dharma Rao Polisetti, Janos Tibor Kodra, Jesper Lau, Paw Bloch, Maria Carmen Valcarce-Lopez, Niels Blume, Mustafa Guzel, Kalpathy Chidambareswaran Santhosh, Adnan M.M. Mjalli, Robert Carl Andrews, Govindan Subramanian, Michael Ankersen, Per Vedso, Anthony Murray, Lone Jeppesen
  • Halo sulfonyl aryl boronates
    Publication number: 20040116701
    Abstract: The present invention relates to halo sulfonyl aryl boronates of the general formula (I): 1
    Type: Application
    Filed: October 30, 2003
    Publication date: June 17, 2004
    Inventors: Per Vedso, Preben Houlberg Olesen, Thomas Hoeg-Jensen
  • Pharmaceutical use of boronic acids and esters thereof
    Publication number: 20040053889
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds, method of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of a range of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Application
    Filed: July 7, 2003
    Publication date: March 18, 2004
    Inventors: Soren Ebdrup, Per Vedso, Poul Jacobsen
  • Use of compounds for decreasing activity of hormone-sensitive
    Publication number: 20030166690
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Application
    Filed: December 13, 2002
    Publication date: September 4, 2003
    Inventors: Soren Ebdrup, Johannes Cornelis de Jong, Poul Jacobsen, Holger Claus Hansen, Per Vedso
  • Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
    Publication number: 20030166644
    Abstract: Use of compounds to inhibit hormone-sensitive lipase, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and novel compounds. The present compounds are inhibitors of hormone-sensitive lipase and may be useful in the treatment and/or prevention of medical disorders where a decreased activity of hormone-sensitive lipase is desirable.
    Type: Application
    Filed: December 13, 2002
    Publication date: September 4, 2003
    Inventors: Soren Ebdrup, Johannes Cornelis de Jong, Poul Jacobsen, Holger Claus Hansen, Per Vedso