Patents by Inventor Per Vedsoe

Per Vedsoe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF
    Publication number: 20250084106
    Abstract: The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 13, 2025
    Inventors: Hiromu Takiguchi, Akinobu Higashi, Takashi Inaba, Takashi Watanabe, Tsubasa Takeichi, Anders Klarskov Petersen, Per Vedsoe, Kim Lebek Jensen, Jan Bornholdt, Soren Ebdrup
  • Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof
    Patent number: 12195481
    Abstract: The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
    Type: Grant
    Filed: April 19, 2023
    Date of Patent: January 14, 2025
    Assignees: Japan Tobacco Inc., Leo Pharma A/S
    Inventors: Hiromu Takiguchi, Akinobu Higashi, Takashi Inaba, Takashi Watanabe, Tsubasa Takeichi, Anders Klarskov Petersen, Per Vedsoe, Kim Lebek Jensen, Jan Bornholdt, Soren Ebdrup
  • PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF
    Publication number: 20240140967
    Abstract: The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
    Type: Application
    Filed: April 19, 2023
    Publication date: May 2, 2024
    Inventors: Hiromu Takiguchi, Akinobu Higashi, Takashi Inaba, Takashi Watanabe, Tsubasa Takeichi, Anders Klarskov Petersen, Per Vedsoe, Kim Lebek Jensen, Jan Bornholdt, Soren Ebdrup
  • Process for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives and synthetic intermediates thereof
    Patent number: 11673900
    Abstract: The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S,4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: June 13, 2023
    Assignees: Japan Tobacco Inc., LEO Pharma A/S
    Inventors: Hiromu Takiguchi, Akinobu Higashi, Takashi Inaba, Takashi Watanabe, Tsubasa Takeichi, Anders Klarskov Petersen, Per Vedsoe, Kim Lebek Jensen, Jan Bornholdt, Soren Ebdrup
  • PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF
    Publication number: 20200216470
    Abstract: The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S, 4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.
    Type: Application
    Filed: December 20, 2017
    Publication date: July 9, 2020
    Inventors: Hiromu Takiguchi, Akinobu Higashi, Takashi Inaba, Takashi Watanabe, Tsubasa Takeichi, Anders Klarskov Petersen, Per Vedsoe, Kim Lebek Jensen, Jan Bornholdt, Soren Ebdrup
  • Urea glucokinase activators
    Patent number: 8362049
    Abstract: This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composition comprising a compound according to the invention and a process for preparing such.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: January 29, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Per Vedsoe, Lise Brown Christiansen
  • Heteroaryl-ureas and their use as glucokinase activators
    Patent number: RE45183
    Abstract: This invention relates to compounds of formula (I) which are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: October 7, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Lone Jeppesen, Per Vedsoe, Michael Ankersen, Jane Marie Lundbeck, Marit Kristiansen, Maria Carmen Valcarce Lopez, Dharma Rao Polisetti, Govindan Subramanian, Robert Carl Andrews, Daniel P. Christen, Jeremy T. Cooper, Kalpathy Chidambareswaran Santhosh