Abstract: A gynecological brachytherapy applicator for use in delivering a radiation dose to a tumor affecting a uterus and a cervix of a patient is described herein. The applicator includes an intrauterine tandem that includes a base portion and a tip portion extending outwardly from the base portion. The tip portion is configured to be inserted within the uterus to facilitate delivering a radiation dose to an area including the uterus and the cervix. The tandem is configured to reduce metal artifacts in MR images of the tandem within the patient to facilitate improving visualization and localization of the tandem in the MR images during MR-guided intracavitary brachytherapy.

Abstract: A gynecological brachytherapy applicator for use in delivering a radiation dose to a tumor affecting a uterus and a cervix of a patient is described herein. The applicator includes an intrauterine tandem that includes a base portion and a tip portion extending outwardly from the base portion. The tip portion is configured to be inserted within the uterus to facilitate delivering a radiation dose to an area including the uterus and the cervix. The tandem is configured to reduce metal artifacts in MR images of the tandem within the patient to facilitate improving visualization and localization of the tandem in the MR images during MR-guided intracavitary brachytherapy.

Abstract: A micro-radiation therapy apparatus includes an isotope-based micro-radiotherapy brachytherapy small animal irradiator useful for radiating a biological system, the irradiator having an external radiation source proximate the biological system comprising a collimated radiation beam. A method of effectively irradiating at least one cell in a biological system includes applying micro-radiation from an isotope-based micro-radiation small animal irradiator, the irradiator having an external radiation source proximate the biological system including a collimated radiation beam to a target cell of the biological system.