Patents by Inventor Perurmadom Ramaiyer Mahadevan

Perurmadom Ramaiyer Mahadevan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombolytic enzyme and a process for its preparation
    Patent number: 7776574
    Abstract: The invention relates to a thrombolytic enzyme referred to as Thrombinase having a molecular weight of 31,000 to 32,000. Such a thrombolytic enzyme can be used for dissolving blood clots. The process comprises culturing a filtrate of Bacillus sphaericus sero type H5a 5b, removing the cell, subjecting the cell supernatant to filtration, salting out the retentate, subjecting the precipitate to dialysis, reprecipitating the precipitate and then reconstituting in buffer and finally decolourizing, purifying and dialyzing.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: August 17, 2010
    Assignees: National Research Development Corporation, Malladi Drugs & Pharmaceuticals Ltd.
    Inventors: Perurmadom Ramaiyer Mahadevan, Sita Mahadevan, legal representative, Subrahmanyam Chivukula Sekar, Sundaramurthy Suresh Babu
  • Novel thrombolytic enzyme and a process for its preparation
    Publication number: 20090285793
    Abstract: The invention relates to a thrombolytic enzyme referred to as Thrombinase having a molecular weight of 31,000 to 32,000. Such a thrombolytic enzyme can be used for dissolving blood clots. The process comprises culturing a filtrate of Bacillus sphaericus sero type H5a 5b, removing the cell, subjecting the cell supernatant to filtration, salting out the retentate, subjecting the precipitate to dialysis, reprecipitating the precipitate and then reconstituting in buffer and finally decolourizing, purifying and dialyzing.
    Type: Application
    Filed: October 12, 2007
    Publication date: November 19, 2009
    Applicants: National Research Development Corporation, Malladi Drugs & Pharmaceuticals Ltd.
    Inventors: Perurmadom Ramaiyer Mahadevan, Sita Mahadevan, Subrahamanyam Chivukula Sekar, Sundaramurthy Suresh Babu