Patents by Inventor Petar Lenert

Petar Lenert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunomodulatory oligonucleotides and methods of use therefor
    Patent number: 7879812
    Abstract: The present invention is drawn a new class of oligodeoxynucleotides (ODNs) that inhibit ODN-activation of Toll-like receptor (TLR)9. Particular 4-5 base extensions at the 5? and of the previously described core inhibitory ODN sequence enhances their inhibitory activity against human cells expressing human TLR9. Methods of use also are provided.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: February 1, 2011
    Assignee: University of Iowa Research Foundation
    Inventors: Robert Ashman, Petar Lenert
  • IMMUNOMODULATORY OLIOGONUCLEOTIDES AND METHODS OF USE THEREFOR
    Publication number: 20100081706
    Abstract: The present invention is drawn a new class of oligodeoxynucleotides (ODNs) that inhibit ODN-activation of Toll-like receptor (TLR) 9. Particular 4-5 base extensions at the 5? and of the previously described core inhibitory ODN sequence enhances their inhibitory activity against human cells expressing human TLR9. Methods of use also are provided.
    Type: Application
    Filed: August 4, 2008
    Publication date: April 1, 2010
    Applicant: University of Iowa Research Foundation
    Inventors: ROBERT ASHMAN, Petar Lenert
  • Immunoglobulin-binding polypeptides
    Patent number: 5306812
    Abstract: A method of separating V.sub.H containing immunoglobulins by admixing an immunoglobulin binding peptide is described. The polypeptide of the invention is capable of binding to heavy chain variable regions of antibodies in an antigen independent manner and can separate antigen/antibody complexes.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: April 26, 1994
    Assignee: The Regents of the University of California
    Inventors: Maurizio Zanetti, Petar Lenert, Edward Golub, Daniel Kroon
  • Immunoglobulin-binding polypeptides
    Patent number: 5231167
    Abstract: Polypeptides having a segment capable of binding to immunoglobulin heavy chain variable regions (V.sub.H) in an antigen independent manner have been described. These polypeptides can be used to form complexes with V.sub.M containing molecules for diagnostic purposes and to increase the affinity of the antibody for its antigen. Additionally, the polypeptides of the invention can be used to separate V.sub.H containing molecules from solution to form isolated V.sub.H or V.sub.H depleted compositions.
    Type: Grant
    Filed: September 8, 1989
    Date of Patent: July 27, 1993
    Assignee: The Regents of the University of California
    Inventors: Maurizio Zanetti, Petar Lenert, Edward Golub, Daniel Kroon