Abstract: Provided herein are drug delivery devices, comprising a scaffold comprising one or more biocompatible materials, one or more chambers containing a plurality of cells, one or more membranes, and one or more nutrient supplementation systems. Also provided are methods of treating or preventing diseases and disorders in a subject in need thereof, comprising administering to the subject the drug delivery devices disclosed herein, and methods of making the drug delivery devices disclosed herein.

Abstract: Disclosed herein are buccal implant devices comprising a body having a non-cylindrical geometry, the body adapted to be disposed within the oral cavity of a patient (e.g., the oral mucosa of a patient), and one or more pharmaceutically active ingredients. Also disclosed are methods of using the buccal implant devices in treating or preventing medical conditions.

Abstract: Provided are methods for inhibiting the progression of an inflammatory mediated mucosal infection. The methods include administering an effective amount of an anti-inflammatory agent. Also provided are compositions and articles of manufacture for preventing, and inhibiting the activation and progression of a mucosal infection.

Abstract: Provided are methods for determining the presence of a specific nucleic acid sequence in a non-fluid biological sample. Also provided are methods for detecting and determining the whole body viral burden of a virus in a subject.

Abstract: Chemotactin, diethyl phthalate, is shown to be a chemoattractant secreted by H. pylori. Chemotactin attracts phagocytic cells with a resulting inflammatory episode. Chemotactin and its metabolites may be used for diagnosis and monitoring courses of infection by H. pylori or other chemotactin secreting organisms. In addition, chemotactin may be used in research for studying the inflammatory process, for identifying new drugs for modulating chemoattraction and activation of phagocytic cells, and for inducing an inflammatory response as a therapeutic intervention.