Abstract: The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the present invention provides methods for delivering saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The delivery methods and materials herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies.

Abstract: Disclosed herein is a modular computing device that provides a user options to upgrade an existing computing device as improved expansion units become available without rendering the underlying base unit obsolete. The base unit of the modular computing device receives high-voltage AC power and one or more power supplies within the base unit converts the AC power to low-voltage DC power that is consumed within the base unit. An AC power transfer unit transfers AC power from the base unit to an expansion unit installed within an expansion dock of the base unit. One or more power supplies within the expansion unit convert the received AC power to low-voltage DC power that is consumed within the expansion unit.

Abstract: An example method for adjusting operation of an integrated circuit includes testing a plurality of electronic elements of the integrated circuit including one or more redundant electronic elements designated as inactive according to a manufacturer's default configuration of the integrated circuit to determine one or more operating parameters of the integrated circuit. The method further includes selecting a subset of electronic elements from the plurality of electronic elements based on the one or more operating parameters, wherein the subset of electronic elements is designated as active according to an updated configuration of the integrated circuit, and controlling operation of the integrated circuit using the updated configuration instead of the manufacturer's default configuration.

Abstract: A computing device is provided that includes a processor, a primary power supply, and a voltage regulation module. The voltage regulation module is configured to determine a load line for the processor and monitor a voltage and a current to the processor. While monitoring the voltage and current, the voltage regulation module is further configured to regulate the voltage to the processor to trend toward a voltage setpoint defined by the load line. While regulating the voltage, the voltage regulation module is further configured to clamp the load line at a clamping voltage to limit the regulated voltage output by the voltage regulation module from falling below a predetermined device minimum operation voltage when the monitored current exceeds a device maximum current value. The voltage regulation module is further configured to output electrical power at the regulated voltage to the processor.

Abstract: A computing device is provided that includes a processor, a primary power supply, and a voltage regulation module. The voltage regulation module is configured to determine a load line for the processor and monitor a voltage and a current to the processor. While monitoring the voltage and current, the voltage regulation module is further configured to regulate the voltage to the processor to trend toward a voltage setpoint defined by the load line. While regulating the voltage, the voltage regulation module is further configured to clamp the load line at a clamping voltage to limit the regulated voltage output by the voltage regulation module from falling below a predetermined device minimum operation voltage when the monitored current exceeds a device maximum current value. The voltage regulation module is further configured to output electrical power at the regulated voltage to the processor.

Abstract: An example method for adjusting operation of an integrated circuit includes testing a plurality of electronic elements of the integrated circuit including one or more redundant electronic elements designated as inactive according to a manufacturer's default configuration of the integrated circuit to determine one or more operating parameters of the integrated circuit. The method further includes selecting a subset of electronic elements from the plurality of electronic elements based on the one or more operating parameters, wherein the subset of electronic elements is designated as active according to an updated configuration of the integrated circuit, and controlling operation of the integrated circuit using the updated configuration instead of the manufacturer's default configuration.

Abstract: A method for controlling a cooling system for a device includes determining a power load of the processing system, determining a power load of the device, setting a first thermal setpoint based at least in part on the power load, determining a temperature of the device, adjusting a response of the cooling system based at least in part on the first thermal setpoint, detecting a change in the power load of the device to a higher power load having a higher magnitude acoustic response, in response to detecting the change in the power load, setting a second thermal setpoint having a lower magnitude acoustic response at the higher power load, the second thermal setpoint being based at least in part on a determined second corresponding acoustic response curve, and adjusting the response of the cooling system based at least in part on the second thermal setpoint.

Abstract: A computing device is provided that includes a processor, a primary power supply, and a voltage regulation module. The voltage regulation module is configured to determine a load line for the processor and monitor a voltage and a current to the processor. While monitoring the voltage and current, the voltage regulation module is further configured to regulate the voltage to the processor to trend toward a voltage setpoint defined by the load line. While regulating the voltage, the voltage regulation module is further configured to clamp the load line at a clamping voltage to limit the regulated voltage output by the voltage regulation module from falling below a predetermined device minimum operation voltage when the monitored current exceeds a device maximum current value. The voltage regulation module is further configured to output electrical power at the regulated voltage to the processor.

Abstract: Disclosed herein is a modular computing device that provides a user options to upgrade an existing computing device as improved expansion units become available without rendering the underlying base unit obsolete. The base unit of the modular computing device receives high-voltage AC power and one or more power supplies within the base unit converts the AC power to low-voltage DC power that is consumed within the base unit. An AC power transfer unit transfers AC power from the base unit to an expansion unit installed within an expansion dock of the base unit. One or more power supplies within the expansion unit convert the received AC power to low-voltage DC power that is consumed within the expansion unit.

Abstract: A method for controlling a cooling system for a device includes determining a power load of the processing system, determining a power load of the device, setting a first thermal setpoint based at least in part on the power load, determining a temperature of the device, adjusting a response of the cooling system based at least in part on the first thermal setpoint, detecting a change in the power load of the device to a higher power load having a higher magnitude acoustic response, in response to detecting the change in the power load, setting a second thermal setpoint having a lower magnitude acoustic response at the higher power load, the second thermal setpoint being based at least in part on a determined second corresponding acoustic response curve, and adjusting the response of the cooling system based at least in part on the second thermal setpoint.

Abstract: An edge plated printed circuit board (PCB) improves radiated emission performance by enhancing ground shielding on the PCB and improving the physical and electrical connection between the PCB and external EMI suppression components including an EMI chassis and gaskets. Inner ground layers within a multi-layer PCB are configured to physically extend to an edge of the PCB, which is plated using copper electroplating, so that copper ground strips disposed at the top and bottom surfaces of the PCB and the inner ground layers are all electrically coupled to the plated edge. In some embodiments, the ground strips can be made thinner compared to conventional arrangements, or be eliminated altogether as a result of the direct connection between the edge plated PCB and external EMI shields.

Abstract: A communication system where first and second devices communicate concurrently and bidirectionally over a single wire and a ground. The second device can be a computing device having a powered component which requires a certain power output, for instance, and the first device may be a power supply unit. The second device provides a signal on a control line (the single wire) which is characterized by a frequency, pulse width, duty cycle and/or an amplitude which is associated with a message from the second device. The first device recognizes the message in the signal and invokes a corresponding function, such as by enabling a corresponding power supply. The power supply provides power to the second device via a separate power line. Further, the first device modifies the signal, without adding power, to provide a message from the first device, concurrent with the message from the second device.

Abstract: An edge plated printed circuit board (PCB) improves radiated emission performance by enhancing ground shielding on the PCB and improving the physical and electrical connection between the PCB and external EMI suppression components including an EMI chassis and gaskets. Inner ground layers within a multi-layer PCB are configured to physically extend to an edge of the PCB, which is plated using copper electroplating, so that copper ground strips disposed at the top and bottom surfaces of the PCB and the inner ground layers are all electrically coupled to the plated edge. In some embodiments, the ground strips can be made thinner compared to conventional arrangements, or be eliminated altogether as a result of the direct connection between the edge plated PCB and external EMI shields.

Abstract: A communication system where first and second devices communicate concurrently and bidirectionally over a single wire, in addition to a ground. The second device can be a computing device having a powered component which requires a certain power output, for instance, and the first device may be a power supply unit. The second device provides a signal on a control line (the single wire) which is characterized by a frequency, pulse width, duty cycle and/or an amplitude which is associated with a message from the second device. The first device recognizes the message in the signal and invokes a corresponding function, such as by enabling a corresponding power supply. The power supply provides power to the second device via a separate power line. Further, the first device modifies the signal, without adding power, to provide a message from the first device, concurrent with the message from the second device.

Abstract: A printed wiring assembly comprising, a printed wiring board, a ball grid array coupled to the printed wiring board, and a high density surface mount part array disposed on the printed wiring board.

Abstract: According to the present invention, six die-cut CD-ROM labels are provided on a sheet in a vertical pattern with labels offset from a scored or perforated centerline of the other three. Each set of three is spaced from the outer edges of the sheet and by folding the sheet in half and removing a corner tab an adhesive edge of one of the labels is exposed which can be applied to a disk manually held on a printed outline of the disk on the back of the sheet, obviating the need for use of any applicator centering device, or holder for the disk, and/or label.

Abstract: In accordance with the invention, a fixture is provided to receive a label to be applied to a truncated CD disc. The fixture includes a base having an oval-shaped well of a dimension approximately the shape of the label. The label, after printing indicia thereon, is placed adhesive side up in the well of the fixture. Since the well also approximates the shape of the CD disc, the disc may be placed in the well first, within the bounds of the well of the fixture, with its unwritten side facing up. The disc or label is then overlaid on the other manually in the well, and pressed in place, to adhere the label to the disc. A pair of oppositely disposed cutouts are provided in the fixture to enable the composite card and adhered label to be removed from the fixture by inserting the fingers beneath the laminate and lifting it up from the fixture.

Abstract: In accordance with the invention, a fixture is provided to receive a label to be applied to a CD disc. The fixture includes a base having a well of a dimension approximately the shape of the label and CD disc. The label, after printing indicia thereon, is placed adhesive side up in the well of the fixture. Since the well also approximates the shape of the CD disc, the disc may be placed in the well first, within the bounds of the well of the fixture, with its unwritten side facing up. The disc or label is then overlaid on the other manually in the well, and pressed in place, to adhere the label to the disc. A pair of oppositely disposed cutouts are provided in the fixture to enable the composite card and adhered label to be removed from the fixture by inserting the fingers beneath the laminate and lifting it up from the fixture.

Abstract: A blank having a defined pattern of reduced strength, allowing separation along said defined pattern, the pattern defining a video cassette box from a single sheet having first and second face portions, one or more side flaps for forming a parallelepiped, one or more reinforcing tabs for increasing the durability of the box and one or more top tabs for forming an enclosure at one end of the box.

Abstract: A method of stabilizing soil and aggregate for structural purposes including the step of mixing with water: (a) a soil aggregate base material; (b) a stabilization composition comprising: (i) an alkali metal silicate or other suitable gel precursor, and (ii) optionally a cation; and (c) a minimum amount of 1% of cement based on the weight of the resulting mixture, whereby sufficient water is added to the resulting mixture to hydrate the cement and thereby provide a stabilized soil aggregate matrix suitable for use in a structure.