Abstract: A drug delivery device comprising a main body extending between distal and proximal ends comprising a hollow cylinder comprising an outer and an inner surface, wherein the inner surface comprises threads; a screw within the main body, comprising a hollow cylinder comprising an inner and an outer surface, wherein said outer surface comprises threads, wherein threads of outer surface of the screw are engaged with threads of inner surface of the main body; a plunger extending between distal and proximal ends, wherein the distal end of the plunger engages the proximal end of the screw; and a drug container extending between distal and proximal ends, and comprising a change in cross section from proximal to distal end, wherein the container is within the screw, and wherein the proximal end of the drug container is fixed to the screw and distal end of the container is fixed to the main body.

Abstract: A medication injector that has an alert indicator that alerts the user when the medication injector is approaching near the end of its medication supply is disclosed. The alert indicator gives the user an opportunity to make preparations to obtain additional medication for the injector if there is an insufficient amount of medication in the injector to enable the user to dispense the required dosage amount with the next injection. Initially, the alert indicator is not visible to the user, but becomes visible to the user when the injector is near empty.

Abstract: This disclosure relates to dry powder inhalers and drug products and, more particularly to polyflux colliders useful for de-agglomerating dry powder in dry powder dispensers. Various embodiments provide drug products, dry powder inhalers and polyflux collider arrangement. With various embodiments of the present invention, a polyflux collider is provided which utilizes colliding streams of dry powder to provide desirable de-agglomerating capability for dry powder dispensers.

Abstract: This invention relates to dry powder inhalers and drug products and, more particularly to polyflux colliders useful for de-agglomerating dry powder in dry powder dispensers. Various embodiments provide drug products, dry powder inhalers and polyflux collider arrangement. With various embodiments of the present invention, a polyflux collider is provided which utilizes colliding streams of dry powder to provide desirable de-agglomerating capability for dry powder dispensers.

Abstract: A delivery device (10) for the delivery of at least one dose of a composition into a nasal cavity, the device has a discharge member (12) formed for insertion into a nasal cavity, a discharge aperture (20) being formed therethrough and a body (14) containing a reservoir (24) of at least one dose, the body is elongated and generally extending along a longitudinal axis (16), wherein the discharge member (12) extends along a secondary axis (18), the secondary axis (18) intersecting with, and being disposed transversely to the longitudinal axis (16).

Abstract: Various embodiments of the present invention provide a delivery device (10) for the delivery of a dose of liquid into a nasal cavity. The device includes a discharge member (12) formed for insertion into a nasal cavity, a discharge aperture (14) being formed there through. An elastomeric surface (26) is disposed about the discharge aperture (14).

Abstract: A container having signaling capability is disclosed for use with medicine and other pharmaceutical related products. The container preferably includes a conventional bottle-type body with a rotatably secured closure. A sensor means is structured to determine the position of the closure and thereby provide an indication of cap rotation indicative of the patient using the medicine. A processing means and display means are also included in the container to provide an indication of the current state of the container with respect to its contents. In addition, the container can include a button means to permit a user of the container to scroll through indicia shown on the display means. In another aspect of the container, a base station is provided for transmitting data to/from a signal means incorporated into the container. The base station includes a body having at least one receptacle for suitably receiving a container therein. A method of using the container is also provided.

Abstract: A compound motion cutting device for cutting a work piece includes a tubular member having first and second ends, a pair of operating members and a drive rod having first and second ends and extending longitudinally into the tubular member. One of the operating members is secured to the first end of the tubular member and the first end of the drive rod is secured to the other of the operating members. An anvil is supported proximate the second end of the tubular member and includes a surface for supporting the work piece and a slot extending through the support surface. A cutting member includes a first end pivotally attached to the second end of the drive rod and a cam slot extending laterally therethrough. A pin is supported proximate the second end of the tubular member an extends through the cam slot in the cutting member.

Abstract: Disclosed are pre-filled syringes equipped with an improved plunger having a plunge insert and a plunger rod, characterized by a leak-proof seal and easy sliding property.

Abstract: An apparatus for deploying a radially self-expanding stent includes proximal and distal sleeves respectively containing proximal and distal end portions of the stent in a reduced radius delivery configuration. The sleeves can abut one another and thus contain the entire length of the stent, or may be used in combination with an outer catheter surrounding the sleeves and containing the medial region of the stent. In either event, once the stent and sleeves are positioned at the intended fixation site, the sleeves are moved axially with respect to one another to permit radial self-expansion of the stent only over its medial region, while the sleeves continue to contain the axially outward regions of the stent. Eventually, upon sufficient movement of the sleeves axially relative to one another, the stent becomes totally free of the sleeves, resulting in radial expansion over the entire stent length.

Abstract: A thermal printing device or the like and a tape or tape-ribbon cartridge designed for operative insertion into and use with such device. The device and cartridge of the present invention includes a tape drive system for driving the tape or tape and ribbon through the thermal printing device including a drive roller connected with the machine and a corresponding drive roller mounted within the cartridge and biased toward the machine drive roller. The device and cartridge of the present invention also includes an alignment system comprising a floating alignment member for insuring proper transfer alignment between the platen and the printhead.

Abstract: A switch (10) which uses optical signals propagating through an air media is disclosed. Transmitters (14a-14n) radiate light along projection openings (40) through a solid, opaque housing (12). The projection openings (40) parallel each other and substantially reside in a lower plane (32) within the housing (12). Periscopic plugs (30) reflect such light upward along an intermediate direction (38) within the plugs (30) and out from the plugs (30) into incidence openings (42). The incidence openings (42) parallel each other and substantially reside in an upper plane (34) within the housing (12). Optical receivers (16a-16n) receive light propagating in the incidence openings (42). The incidence openings (42) reside substantially perpendicular to the projection openings (40).

Abstract: A flushing mechanism for flushing a toilet bowl with a reduced amount of water. The flushing mechanism includes a containment vessel adapted to fit in a standard-sized toilet tank and means within the containmment vessel for forcing water out of the vessel into the bowl to be flushed. In a first embodiment, the containment vessel includes an elastic bladder which is filled with the liquid and expands to provide the additional pressure. In a second embodiment, a piston spring system forces liquid out of the containment vessel to flush the bowl. A hydraulic actuation system is also provided for actuating the flushing mechanisms.