Patents by Inventor Peter A. Cohen

Peter A. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150343057
    Abstract: This document provides methods and materials related to using inhibitors of IL-9 signaling in conjunction with chemotherapy to treat cancer (e.g., solid tumors). For example, methods and materials for using inhibitors of IL-9 signaling (e.g., anti-IL9 antibody preparations) in conjunction with chemotherapy to treat cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) or to reduce the growth rate of cancer (e.g., solid tumors such as breast cancer tumors or colon cancer tumors) within a mammal are provided.
    Type: Application
    Filed: April 9, 2015
    Publication date: December 3, 2015
    Inventors: Dominique B. Hoelzinger, Sandra J. Gendler, Peter A. Cohen, Ana L. Dominguez, Shannon E. Smith, Joseph Lustgarten
  • Publication number: 20150299290
    Abstract: A glycolipopeptide comprising a carbohydrate component, a lipid component, and a MUC1 peptide component that induces both a humoral and a cellular immune response for use as a therapeutic or prophylactic vaccine.
    Type: Application
    Filed: April 24, 2015
    Publication date: October 22, 2015
    Inventors: GEERT-JAN BOONS, MARGARETHA WOLFERT, SANDRA J. GENDLER, VANI LAKSHMINARAYANAN, PETER A. COHEN
  • Publication number: 20130236486
    Abstract: A glycolipopeptide comprising a carbohydrate component, a lipid component, and a MUC1 peptide component that induces both a humoral and a cellular immune response for use as a therapeutic or prophylactic vaccine.
    Type: Application
    Filed: June 10, 2011
    Publication date: September 12, 2013
    Applicants: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, UNIVERSITY OF GEORGIA RESEARCH FOUNDATION,INC
    Inventors: Geert-Jan Boons, Margaretha Wolfert, Sandra J. Gendler, Vani Lakshminarayanan, Peter A. Cohen
  • Patent number: 8247227
    Abstract: A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: August 21, 2012
    Assignees: The Cleveland Clinic Foundation, Trustees of the University of Pennsylvania, National Institutes of Health
    Inventors: Peter A. Cohen, Suyu Shu, Gary K. Koski, Charles S. Carter, Laura Carter, legal representative, Brian J. Czerniecki
  • Publication number: 20100272700
    Abstract: A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
    Type: Application
    Filed: August 28, 2007
    Publication date: October 28, 2010
    Inventors: Peter A. Cohen, Suyu Shu, Gary K. Koski, Charles S. Carter, Brian J. Czerniecki
  • Publication number: 20060106774
    Abstract: A method, system, and computer-readable medium is described for facilitating interactions between task requesters who have tasks that are available to be performed and task performers who are available to perform tasks. In some situations, the tasks to be performed are human performance tasks that use cognitive and other mental skills of human task performers, such as to employ judgment, perception and/or reasoning skills of the human task performers. In addition, in some situations the performance of tasks is facilitated by using information about qualifications of task performers that are related to performance of tasks Various types of qualifications about task performers can be specified, and qualification information can be specified and used in various ways, such as to limit task performance and/or access to other functionality to users having appropriate qualifications.
    Type: Application
    Filed: November 16, 2004
    Publication date: May 18, 2006
    Inventors: Peter Cohen, Daniel Sanderson, Mikhail Seregine, Brett Kiefer, Jang Goo, Yuhui Jin
  • Publication number: 20060106675
    Abstract: A method, system, and computer-readable medium is described for facilitating interactions between task requesters who have tasks that are available to be performed and task performers who are available to perform tasks. In some situations, the tasks to be performed are human performance tasks that use cognitive and other mental skills of human task performers, such as to employ judgment, perception and/or reasoning skills of the human task performers. In addition, in some situations the available tasks are submitted by human task requesters via application programs that programmatically invoke one or more application program interfaces of an electronic marketplace in order to request that the tasks be performed and to receive corresponding results of task performance in a programmatic manner, so that an ensemble of unrelated human agents can interact with the electronic marketplace to collectively perform a wide variety and large number of tasks.
    Type: Application
    Filed: November 16, 2004
    Publication date: May 18, 2006
    Inventors: Peter Cohen, Daniel Sanderson, Mikhail Seregine, Brett Kiefer, Jang Goo, Jeffrey Bezos
  • Patent number: 6754368
    Abstract: An object recognition and tracking system having detector arrays (60, 70), each detector array (60, 70) including a first type of detector (95) and a second type of detector (96). The first type of detector (95) detects the presence of an object such as by changing contrast boundaries and hence objects (91, 92) that move in a detector space (90) and the second type of detector (96) focuses in on the defined object (91, 92) and to recognize, identify or record it. The detectors (95, 96) may be video, radar, microwave, radio frequency, infrared, millimeter wave, or transponder interrogators or a combination of these. Tracking of objects (91, 92) between adjoining detector spaces (90, 90) may also be done.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: June 22, 2004
    Assignee: Beonic Corporation Pty. Ltd
    Inventor: Peter Cohen
  • Patent number: 6358736
    Abstract: The present invention relates to methods of increasing the antigen presenting ability of leukemia cells by contacting them with an agent which increases the intracellular calcium level. Methods of treating leukemia are also disclosed.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: March 19, 2002
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Peter A. Cohen, Brian J. Czerniecki, Gary K. Koski, David E. Weng, Charles Carter, John O. Ojeifo, Gretchen N. Schwartz
  • Patent number: 6010905
    Abstract: The present invention relates to methods of increasing the antigen presenting ability of monocytes by contacting them with an agent which increases the intracellular calcium level. Methods of obtaining the monocytes are also disclosed. In addition, the present invention relates to methods of inducing bone marrow progenitor cells and endothelial cells to express molecules involved in generating immune responses. Methods of modulating the expression of molecules involved in generating immune responses are also disclosed, as are methods of treating cancer and leukemia.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: January 4, 2000
    Assignee: The United States of America as represented by the Department of Health & Human Services
    Inventors: Peter A. Cohen, Brian J. Czerniecki, Gary K. Koski, David E. Weng, Charles Carter, John O. Ojeifo, Gretchen N. Schwartz
  • Patent number: 5643786
    Abstract: A method of isolating dendritic cells is described. This method involves elutriating peripheral blood samples in at least four flow rates from an elutriation rotor. Calcium ionophore is used to stimulate monocytes isolated during the process into dendritic cells. Treatments for diseases involving re-introduction of activated dentritic cells are also described.
    Type: Grant
    Filed: January 27, 1995
    Date of Patent: July 1, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Peter A. Cohen, Brian J. Czerniecki, Charles Carter, Daniel H. Fowler, Hyun Kim
  • Patent number: 4458020
    Abstract: A system for conducting an immunoassay in a single chamber, by concentrating antibodies for antigenic components on microbeads treated for binding immunological components, physically separating the fluid from which the immunological active component is separated, and determining the amount of immunological component collected on the beads, comprising a multiple-chamber dispensing cylinder.
    Type: Grant
    Filed: November 15, 1982
    Date of Patent: July 3, 1984
    Assignee: Quidel
    Inventors: Joseph W. Bohn, Peter A. Cohen, Bruce L. Zuraw
  • Patent number: 4424279
    Abstract: A method and apparatus for conducting an immunoassay. The apparatus features a cylindrical tube having one open end into which a plunger filter assembly is slidably fitted. The filter assembly is composed of a plunger filter cylinder open at both ends, a seal fixed to the proximal end of the plunger filter cylinder and a dome-shaped filter inside of and closing the proximal end of the plunger filter cylinder, and beads sensitized with an immunologically reactive material, such as an antibody.
    Type: Grant
    Filed: August 12, 1982
    Date of Patent: January 3, 1984
    Assignee: Quidel
    Inventors: Joseph W. Bohn, Peter A. Cohen, Bruce L. Zuraw