Abstract: System and method for rehabilitating a muscle and monitoring such rehabilitation are provided, the system including a user input receiver for receiving stimulation parameter inputs from a user, a stimulator for generating stimulations to be applied to a patient's body based on the stimulation parameter inputs, a signal receiver to receive, detect, and record a signal containing an evoked potential generated by the body in response to the stimulations, a signal processor for processing the recorded signal, for example, by amplifying, filtering, digitizing and temporal averaging the recorded signal, a trigger detector to alert the signal processor module when stimulations are generated to enable synchronization of the response signal with the stimulus for accurate temporal averaging, and an output display for providing data representative of the evoked potential to the user.

Abstract: The subject invention relates to the detection, diagnosis and risk stratification of clinical events such as acute coronary syndrome, in patients with signs and symptoms of suspected cardiac origin. In one embodiment, a clinical event in a patient is diagnosed by obtaining the patient's ECG, and at least one in vitro diagnostic assay, preferably an assay for a marker of ischemia, and optionally in vitro diagnostic assays for necrotic markers or other cardiac indicators, and combining the foregoing results in an algorithm to provide a diagnosis or a risk stratification of the clinical condition.

Abstract: The subject invention comprises electrochemical methods and devices for in vitro detection of an ischemic event in a patient sample. Following addition of a known amount of a transition metal ion to the patient sample, electrodes are used to measure the current or potential difference of non-sequestered transition metal ion in the sample. The amount of non-sequestered transition metal ion in the sample reflects the degree of modification to albumin that is the result of an ischemic event.

Abstract: Diagnostic test devices, including diagnostic strip tests, are provided in which identifying information and the test result are machine-readable. Also provided are methods for obtaining identifying information and test results from the diagnostic test devices.

Abstract: The subject invention comprises electrochemical methods and devices for in vitro detection of an ischemic event in a patient sample. Following addition of a known amount of a transition metal ion to the patient sample, electrodes are used to measure the current or potential difference of non-sequestered transition metal ion in the sample. The amount of non-sequestered transition metal ion in the sample reflects the degree of modification to albumin that is the result of an ischemic event.

Abstract: Diagnostic test devices, including diagnostic strip tests, are provided in which identifying information and the test result are machine-readable. Also provided are methods for obtaining identifying information and test results from the diagnostic test devices.

Abstract: Methods and apparatus are provided for cauterizing predetermined volumes of abnormal biological tissue using a user selectable or adjustable energy applicator including two or more electrodes having electrode parameters configured cause cauterization of predetermined volumes when operated in a bipolar mode. The energy applicators are employed with a control device that couples the energy applicators to a power source and includes circuitry for interrupting activation of the energy applicator when the current between the two or more electrodes decreases more than a predetermined amount from the current sensed upon initial activation of the energy applicator.

Abstract: An ultrasound imaging and biopsy system is provided in which an upper compression member of the system includes a thin, flexible, sterile and disposable membrane that compresses the tissue and permits a biopsy instrument to be readily inserted therethrough. In a preferred embodiment, a table is provided that houses an ultrasound scanning system beneath a sonolucent window forming a lower compression surface. Methods of using the system to perform real-time image-guided biopsy of tissue disposed on the window are also provided.

Abstract: In a cardiomyoplasty system, a rate responsive implantable device is disclosed which controls the stimulation of both the heart and a myoplasty muscle. The metabolic demand is used as a rate response parameter and one or both of the heart and the muscle stimulation are increased with metabolic demand. Under certain conditions, for example, if the muscle is tired, its stimulation is maintained constant or reduced and the cardiac stimulation is used to compensate for increased metabolic demand.

Abstract: A cardiomyoplastic muscle is stimulated electronically using a closed loop control system. As part of the system, a signal sensed the muscle which is characteristic of its condition. If this signal indicates an abnormal condition, then the stimulation of the muscle is modified accordingly.

Abstract: A clinical programming system is disclosed for use with an implanted cardiac pacemaker to automatically determine the minimum pacing energy which is necessary to evoke an atrial depolarization. The system utilizes a series of pacing pulses of progressively decreasing energies to stimulate the atrium and detects following R-waves. The absence of an R-wave indicates the loss of atrial capture.

Abstract: A clinical programming system for use with an implanted cardiac pacemaker to automatically determine the minimum pacing energy which is necessary to evoke an atrial depolarization. The system utilizes a series of pacing pulses of progressively decreasing energies to stimulate the atrium, and detects an evoked response during the AV delay interval that follows each pulse. Initial P-wave intervals are subjected to morphological analysis to generate a P-wave template. Subsequent intervals are similarly analyzed and the results compared with the template. The absence of similarity with the template indicates the loss of atrial capture and that the minimum pacing energy has been reached.

Abstract: A clinical programming system is disclosed for use with an implanted cardiac pacemaker to automatically determine the minimum pacing energy which is necessary to evoke a ventricular depolarization. The system utilizes a series of pacing pulses of progressively decreasing energies to stimulate the ventricle, and detects evoked responses through measurements of the integrals of the R-waves provided by a surface electrocardiogram. Upon loss of capture, the minimum pacing energy is a function of the energy of the last pacing pulse which evoked a ventricular depolarization.

Abstract: A facsimile machine which will print documents which have their corresponding edges aligned. Incoming data is stored in memory. A line of text, as it is bit mapped in memory, is identified. Line scans are taken through the upper and lower regions of the text line. Whichever group has the higher average density is the group associated with the tops of the characters. To print the document, data is read out of the memory in the order in which it was received, or in the reverse order, such that an "up side down" document is reoriented. A determination of the order in which printing should take place is made without requiring the actual recognition of any characters.

Abstract: A dual-chamber metabolic demand, rate adaptive pacemaker that automatically calibrates the correlation between a metabolic demand measurement and an appropriate metabolic demand pacing rate according to the true physiological needs of the body, as determined by a patient's sinus rate when the natural sinus rate is functioning in a reliable manner in the absence of cardiac arrhythmia.

Abstract: A cochlear implant system includes an electrode array (1) comprising multiple platinum ring electrodes in a silastic carrier to be implanted in the cochlea of the ear. A receiver-stimulator (3) containing a semiconductor integrated circuit and other components is implanted in the patient adjacent the ear to receive data information and power through tuned coil (5) using an inductive link (6) from a patient-wearable external speech processor (7) including an integrated circuit and various components which is configured or mapped to emit data signals from an EPROM programmed to suit each patient electrical stimulation perceptions through testing of the patient and his implanted stimulator/electrode using a diagnostic and programming unit (12) connected to the processor by an interface unit (10).

Abstract: A test system for a sealed, sterile package containing a cochlear prosthesis electrode. A light-emitting diode has its two leads in contact with at least two different conducting bands on the electrode. The prosthesis, which is externally-powered, is operated so as to supply a stimulus current between the two bands. If the light-emitting diode is illuminated, proper operation of the prosthesis can be verified without unsealing the package.