Abstract: This document provides methods and materials for detecting misfolded poly peptides. For example, devices (e.g., feeding devices) designed to collect samples from one or more mammals (e.g., one or more cervids) are provided. In some cases, methods and materials that can be used to detect one or more prion diseases (e.g., chronic wasting disease (CWD)) in a population of mammals (e.g., a herd of cervids) based, at least in part, on the presence or absence of misfolded polypeptides in a sample from one or more mammals that was obtained from a feeding device are provided.

Abstract: This document relates to methods and materials for detecting the presence or absence of misfolded polypeptides in a sample. For example, methods and materials for amplifying a sample (e.g., a biological sample or an environmental sample) such that misfolded polypeptides present in the sample can aggregate to form fibrils and/or globular polypeptide aggregates and contacting the amplified sample with a solution containing metal nanoparticles (e.g., gold nanoparticles) or one or more organic dyes (e.g., Congo Red) to detect the presence or absence of fibrils and/or globular polypeptide aggregates are provided. In some cases, methods and materials for determining if a mammal (e.g., a human) has a proteinopathy based, at least in part, in the presence or absence of misfolded polypeptides in a sample obtained from the mammal are provided.

Abstract: The playback of video content upon a display is enhanced through the unobtrusive presentation of extrinsic data upon the same display. A video content feature is rendered on a display. A quantity of extrinsic data relevant to a current time in the video content feature is determined based at least in part on viewing history of a user. A graphical element presenting at least a portion of the extrinsic data is rendered on the display while the video content feature is also being rendered on the display.

Abstract: The playback of video content upon a display is enhanced through the unobtrusive presentation of extrinsic data upon the same display. A video content feature is rendered on a display. A quantity of extrinsic data relevant to a current time in the video content feature is determined based at least in part on viewing history of a user. A graphical element presenting at least a portion of the extrinsic data is rendered on the display while the video content feature is also being rendered on the display.

Abstract: A user viewing a presentation of media content can obtain related supplemental content through the same or a different interface, on the same or a different device. A listener or other such component can attempt to detect information about the media, such as tags present in the media, the occurrence of songs or people in the media, and other such information. The detected information can be analyzed to attempt to identify one or more aspects of the media. The identified aspects can be used to attempt to locate supplemental content that is related to the media content and potentially of interest to the user. The interest of the user can be based upon historical user data, preferences, or other such information. The user can be notified of supplemental content on a primary display, and can access the supplemental content on a secondary display, on the same or a separate device.

Abstract: The playback of video content upon a display is enhanced through the unobtrusive presentation of extrinsic data upon the same display. A video content feature is rendered on a display. It is determined whether to present extrinsic data relevant to a current time in the video content feature based at least in part on appearance control metadata. A graphical element presenting at least a portion of the extrinsic data is rendered on the display while the video content feature is also being rendered on the display in response to determining to present the extrinsic data.

Abstract: A cover may be used in conjunction with a handheld device for physical protection of the handheld device. The cover may have an indicator that is responsive to a signal provided by the handheld device to display different colors or other visual states depending on conditions of the handheld device such as security modes, user modes, and so forth.

Abstract: Communications from digital content consumers may be entered on reader devices as social media posts. Rather than specifying a particular recipient, a consumer may enter a reserved keyword, such as @author, as the recipient. Upon submission, this keyword is automatically replaced with the recipient identifier, such as with the user identifier of the actual author of the currently rendered content item.

Abstract: Described are methods and systems of providing an augmented experience on a user device to facilitate user interaction with one or more virtual items. An augmented image comprising an actual object and a virtual item is generated and presented in a user interface. The user interface allows the user to lock a relative position of the virtual item as presented, such that the user may appear to “move” the virtual item. The user interface may also provide sizing information of the virtual item relative item to the actual object.

Abstract: A user viewing a presentation of media content can obtain related supplemental content through the same or a different interface, on the same or a different device. A listener or other such component can attempt to detect information about the media, such as tags present in the media, the occurrence of songs or people in the media, and other such information. The detected information can be analyzed to attempt to identify one or more aspects of the media. The identified aspects can be used to attempt to locate supplemental content that is related to the media content and potentially of interest to the user. The interest of the user can be based upon historical user data, preferences, or other such information. The user can be notified of supplemental content on a primary display, and can access the supplemental content on a secondary display, on the same or a separate device.

Abstract: Some implementations include displaying media content items on a home screen of a computing device. A display order for a list of media content items may be determined based, at least in part, on a predicted likelihood that an individual one of the plurality of media content items will be selected. A home screen of a user interface may be displayed, according to the determined display order, with a list of a plurality of media content items that are available to the computing device.