Patents by Inventor Peter A. Rice

Peter A. Rice has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multi-antigenic peptide mimics of gonococcal lipo-oligosaccharide (LOS) epitopes
    Patent number: 12629410
    Abstract: In some aspects, the disclosure relates to compositions of peptide mimics useful in the treatment of Neisseria gonorrhoeae (N. gonorrhoeae). In some embodiments, the peptide mimics are multi-antigenic molecules of a conserved gonococcal lipo-oligosaccharaide (LOS) epitope. In some aspects, the disclosure relates to methods of making peptide mimics for the treatment of N. gonorrhoeae. In some aspects, the disclosure relates to methods of using peptide mimics for the treatment of N. gonorrhoeae.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: May 19, 2026
    Assignee: University of Massachusetts
    Inventors: Peter A. Rice, Michael W. Pennington, Sunita Gulati, Jutamas Shaughnessy, Sanjay Ram
  • HUMANIZED ANTIBODIES AGAINST NEISSERIA GONORRHOEAE AND METHODS OF USE THEREOF
    Publication number: 20240294615
    Abstract: Provided are humanized antibodies that bind to the 2C7 epitope of Neisseria gonorrhoeae. Also provided are compositions and methods for treating Neisseria gonorrhoeae infection in a subject in need thereof.
    Type: Application
    Filed: January 10, 2024
    Publication date: September 5, 2024
    Inventors: Jutamas SHAUGHNESSY, Peter A. RICE, Sunita GULATI, Sanjay RAM, Celia SCHIFFER
  • MULTI-ANTIGENIC PEPTIDE MIMICS OF GONOCOCCAL LIPO-OLIGOSACCHARIDE (LOS) EPITOPES
    Publication number: 20220395567
    Abstract: In some aspects, the disclosure relates to compositions of peptide mimics useful in the treatment of Neisseria gonorrhoeae (N. gonorrhoeae). In some embodiments, the peptide mimics are multi-antigenic molecules of a conserved gonococcal lipoohgosaccharaide (LOS) epitope. In some aspects, the disclosure relates to methods of making peptide mimics for the treatment of N. gonorrhoeae. In some aspects, the disclosure relates to methods of using peptide mimics for the treatment of N. gonorrhoeae.
    Type: Application
    Filed: September 22, 2020
    Publication date: December 15, 2022
    Applicant: University of Massachusetts
    Inventors: Peter A. Rice, Michael W. Pennington
  • HUMANIZED 2C7 MONOCLONAL ANTIBODY DIRECTED AGAINST A NEISSERIA GONORRHOEAE LIPOOLIGOSACCHARIDE (LOS) EPITOPE, FOR HUMAN USE
    Publication number: 20210188952
    Abstract: Provided are humanized antibodies that bind to the 2C7 epitope of Neisseria gonorrhoeae. Also provided are compositions and methods for treating Neisseria gonorrhoeae infection in a subject in need thereof.
    Type: Application
    Filed: November 16, 2018
    Publication date: June 24, 2021
    Inventors: Peter A. RICE, Sunita GULATI, Sanjay RAM
  • METHOD AND APPARATUS FOR PREPARING A RADIOLABELED PHARMACEUTICAL
    Publication number: 20200000946
    Abstract: A method for preparing a radiolabeled pharmaceutical. The method comprises passing a mixture that includes a radiolabeled compound through a column that contains an ion exchange resin to retain the radiolabeled compound on the ion exchange resin. At least a portion of the mixture passes through the column without being retained on the ion exchange resin. The method further comprises eluting the radiolabeled compound off the ion exchange resin using an eluting solution (e.g., a sodium chloride solution) to form a radiolabeled pharmaceutical.
    Type: Application
    Filed: March 2, 2018
    Publication date: January 2, 2020
    Inventors: Daniel L. Yokell, Peter A. Rice
  • Methods, compositions and vaccines relating to antibodies
    Patent number: 9475864
    Abstract: The invention provides compositions and methods for screening subjects at risk for contracting meningococcal disease and/or at risk for failing to elicit an immunogenic response to a vaccine against Neisseria meningitidis. The invention also provides kits for carrying out these screens, and improved vaccines against Neisseria meningitidis.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: October 25, 2016
    Assignee: University of Massachusetts
    Inventors: Sanjay Ram, Tathagat Duttaray, Peter A. Rice, Lisa A. Lewis, Sunita Gulati
  • METHODS, COMPOSITIONS AND VACCINES RELATING TO NEISSERIA MENINGITIDIS ANTIBODIES
    Publication number: 20110229522
    Abstract: The invention provides compositions and methods for screening subjects at risk for contracting meningococcal disease and/or at risk for failing to elicit an immunogenic response to a vaccine against Neisseria meningitidis. The invention also provides kits for carrying out these screens, and improved vaccines against Neisseria meningitidis.
    Type: Application
    Filed: September 4, 2009
    Publication date: September 22, 2011
    Applicant: University of Massachusetts
    Inventors: Sanjay Ram, Tathagat Duttaray, Peter A. Rice, Lisa A. Lewis, Sunita Gulati
  • Peptide mimics of conserved gonococcal epitopes and methods and compositions using them
    Patent number: 7871628
    Abstract: The present invention relates to peptide mimics of a conserved gonococcal epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: January 18, 2011
    Assignee: University of Massachusetts
    Inventors: Peter A. Rice, Jutamas Ngampasutadol, Sunita Gulati
  • Peptide mimics of conserved gonococcal epitopes and methods and compositions using them
    Patent number: 7189405
    Abstract: The present invention relates to peptide mimics of a conserved gonococcal epitope of Neisseria gonorrhoeae, which epitope is not found on human blood group antigens. This invention also relates to methods and compositions using such peptide mimics for the prophylaxis of gonorrheal infections.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: March 13, 2007
    Inventors: Peter A. Rice, Jutamas Ngampasutadol, Sunita Gulati
  • Gonococcal anti-idiotypic antibodies and methods compositions using them
    Patent number: 6099839
    Abstract: The present invention relates to anti-against idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: August 8, 2000
    Inventors: Peter A. Rice, Sunita Gulati, Daniel P. McQuillen
  • Gonococcal anti-idiotypic antibodies and methods and compositions using them
    Patent number: 6074641
    Abstract: The present invention relates to anti-idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
    Type: Grant
    Filed: March 29, 1999
    Date of Patent: June 13, 2000
    Inventors: Peter A. Rice, Sunita Gulati, Daniel P. McQuillen
  • Gonococcal anti-idiotypic antibodies and methods and compositions using them
    Patent number: 5939067
    Abstract: The present invention relates to anti-idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: August 17, 1999
    Inventors: Peter A. Rice, Sunita Gulati, Daniel P. McQuillen
  • Gonococcal anti-idiotypic antibodies and methods and compositions using them
    Patent number: 5888509
    Abstract: The present invention relates to anti-idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: March 30, 1999
    Inventors: Peter A. Rice, Sunita Gulati, Daniel P. McQuillen
  • Gonococcal anti-idiotypic antibodies and methods and compositions using them
    Patent number: 5476784
    Abstract: The present invention relates to anti-idiotypic antibodies directed against Neisseria gonorrhoeae. This invention also relates to methods and compositions using such anti-idiotypic antibodies for the prophylaxis, treatment and diagnosis of gonorrheal infections.
    Type: Grant
    Filed: April 6, 1993
    Date of Patent: December 19, 1995
    Inventors: Peter A. Rice, Sunita Gulati, Daniel P. McQuillen