Abstract: A patient interface for delivering breathable gas to a patient includes a sealing portion including a nose tip engagement portion adapted to form a seal with the patient's nose tip, an upper lip engagement portion adapted to form a seal with the patient's upper lip and/or base of the patient's nares, and nostril engagement flaps adapted to form a seal with the patient's nares. The nose tip engagement portion, the upper lip engagement portion, and the nostril engagement flaps are all structured to extend or curve outwardly from a supporting wall defining an air path.

Abstract: Aspects of the present disclosure include methods for identifying a set of fluorophore-biomolecule reagent pairs for characterizing a sample by flow cytometry. Methods according to certain embodiments include calculating a spectral spillover spreading parameter for a plurality of fluorophores, pairing each fluorophore with a biomolecule that is specific for a biomarker of a cell in the sample to generate a plurality of fluorophore-biomolecule reagent pairs, generating an adjusted spillover spreading matrix for the fluorophore-biomolecule reagent pairs based on the spectral spillover spreading parameter of each fluorophore and a biomarker classification parameter and identifying an optimal set of fluorophore-biomolecule reagent pairs based on the calculated spillover spreading values from the adjusted spillover spreading matrix. Systems and non-transitory computer readable storage medium for practicing the subject methods are also provided.

Abstract: The present invention relates generally to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset or predisposition to die onset of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules in respect of which changes to DNA methylation levels are indicative of the onset and/or progression of a large intestine neoplasm, such as an adenoma or adenocarcinoma. The DNA methylation status of the present invention is useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenocarcinomas. Accordingly, in a related aspect the present invention is directed to a method of screening for the onset, predisposition to the onset and/or progression of a neoplasm by screening for modulation in DNA methylation of one or more nucleic acid molecules.

Abstract: An evaporative cooling module may include a cooling media formed from a vapor permeable membrane in which is formed a plurality of pores at a first side and a second side of the vapor permeable membrane. Individual pores of the plurality of pores may be sized to prevent liquid water from passing there through, and enable water vapor to pass there through. The cooling media may be configured to hold liquid water while an air stream is passed through the cooling media. The evaporative cooling module may also include a module inlet to direct liquid water into the cooling media, a module outlet to direct liquid water out of the cooling media, and a frame configured to support the evaporative cooling module.

Abstract: A secure education system including a secure education application, an education content database and a student profile database having a plurality of student profiles that include identification data that identifies a person associated with the student profile and evaluation data that valuates an academic proficiency of the person. The application both providing and dynamically adjusting the educational content based on an associated student profile of a user as well as securely determining the identity of the user in order to validate interactions of the user with the educational content. The verified identity and academic proficiency of a person can be compiled into an academic profile and submitted to academic institutions to support the user as a candidate for admissions.

Abstract: A secure education system including a secure education application, an education content database and a student profile database having a plurality of student profiles that include identification data that identifies a person associated with the student profile and evaluation data that valuates an academic proficiency of the person. The application both providing and dynamically adjusting the educational content based on an associated student profile of a user as well as securely determining the identity of the user in order to validate interactions of the user with the educational content. The verified identity and academic proficiency of a person can be compiled into an academic profile and submitted to academic institutions to support the user as a candidate for admissions.

Abstract: An environmental control system is provided. The environmental control system can include a cooling device and a heating device. The cooling device can lower the temperature of fluid contained within a cold reservoir and the heating device can raise the temperature of fluid contained within a hot reservoir.

Abstract: A patient interface for delivering breathable gas to a patient includes a sealing portion including a nose tip engagement portion adapted to form a seal with the patient's nose tip, an upper lip engagement portion adapted to form a seal with the patient's upper lip and/or base of the patient's nares, and nostril engagement flaps adapted to form a seal with the patient's nares. The nose tip engagement portion, the upper lip engagement portion, and the nostril engagement flaps are all structured to extend or curve outwardly from a supporting wall defining an air path.

Abstract: An environmental control system is provided. The environmental control system can include a heat absorption device and a heat rejection device positioned in containment areas and a reservoir. The containment areas can contain leaks that may occur in the environmental control system and direct the fluid into the reservoir. The reservoir can include an opening that can allow the environmental control system to operate as a low pressure system.

Abstract: A stuffing box assembly for a fluid end of a hydraulic fluid pump includes a first stuffing box member having a first plunger bore configured to receive a plunger of the hydraulic fluid pump and a plurality of seals. The first stuffing box member further comprises a first bore spaced apart from the plunger bore. A second stuffing box member has a threaded stuffing nut bore configured to receive a stuffing nut of the hydraulic fluid pump. The second stuffing box member further comprises a second bore spaced apart from the stuffing nut bore. A fastener is configured to extend through the first and second bores to secure the first stuffing box member to the second stuffing box member.

Abstract: A patient interface for delivering pressurized breathable gas to a patient includes a flexible sealing portion with an orifice and sides that are adapted to engage with and form a seal with sides of the patient's nose. The orifice is configured so that a supply of breathable gas is deliverable to the patient through the orifice. The patient interface also includes a supporting portion that is in contact with and supports the flexible sealing portion. The patient interface further includes a pair of lateral headgear connector arms arranged at an angle with respect to the orifice in the flexible sealing portion. Each lateral headgear connector arm has a headgear tab. The angle between each lateral headgear connector arm and the orifice is adjustable. In addition, the flexibility of the lateral headgear connector arms allows the headgear tabs to touch an outer surface of the flexible sealing portion.

Abstract: A stuffing box assembly for a fluid end of a hydraulic fluid pump includes a first stuffing box member having a first plunger bore configured to receive a plunger of the hydraulic fluid pump and a plurality of seals. The first stuffing box member further comprises a first bore spaced apart from the plunger bore. A second stuffing box member has a threaded stuffing nut bore configured to receive a stuffing nut of the hydraulic fluid pump. The second stuffing box member further comprises a second bore spaced apart from the stuffing nut bore. A fastener is configured to extend through the first and second bores to secure the first stuffing box member to the second stuffing box member.

Abstract: The utility usage of a particular individual occupying a residence may give insight into the individual's current cognitive health and/or to enable provision of various services within the facility for the individual, particularly when monitoring patterns in utility usage over time. To enable accurate and non-invasive utility monitoring, a single-point utility sensor may be secured relative to a utility supply line, and generated signals may be utilized to monitor utility usage and to distinguish between utility fixtures. A centralized computing entity may identify frequency characteristics within the generated data, and may automatically generate one or more machine-learning algorithms to distinguish between utility usage events, without requiring substantial user input.

Abstract: A stuffing box assembly for a fluid end of a hydraulic fluid pump includes a stuffing box unit having a plunger bore configured to receive a plunger of the hydraulic fluid pump and a plurality of seals. The plunger bore extends from a first axial end of the stuffing box unit to a second axial end of the stuffing box unit. The plunger bore includes a first portion configured to receive the plurality of seals and a second portion extending between the first portion and the second axial end. The stuffing box assembly further includes a sensor coupled to the stuffing box unit and configured to determine a fluid pressure within the second portion of the stuffing box unit.

Abstract: A fluid end assembly of a hydraulic fluid pump includes a housing having a bore, a removable valve cover closing the bore, and a retainer engaging the bore. The retainer includes a set screw bore that extends from a first side of the retainer to a second side of the retainer, opposite the first side. The fluid end assembly further includes a set screw. The set screw is threaded into the set screw bore from the first side of the retainer. The set screw is not removable from the second side of the retainer. The first side of the retainer is positioned adjacent to the valve cover.

Abstract: A thermal energy storage (TES) for Concentrated Solar Power (CSP) plants consists of a two-tank molten salt storage. There is a provided need for a thermal energy receiving and storage system for CSP plants. To demonstrate how thermocline TES can be used in the CSPonD concept, a water tank is used for receiving a heat transfer fluid, which includes an absorbing mesh that is mountable within the tank for establishing and maintaining natural stratification resulting in a thermocline zone within the tank, and additionally comprises a plug flow injection system for establishing plug flow within the tank. A method of establishing and maintaining natural stratification, involves pumping cold heat transfer fluid, injecting the cold heat transfer fluid, and controlling the pumping and the injecting, all within the tank.

Abstract: A movable media air handling unit includes cooling media panels that may be moved into or out of an airflow based on whether or not additional cooling is required from the movable cooling media panels. Moving the cooing media panels out of the air flow reduces flow restrictions/pressure drop through the movable media air handling unit. In some embodiments, various types of movable cooling media panels may be used, such as liquid coolant coil panels, gaseous coolant coil panels, evaporative cooling panels, or other types of panels.

Abstract: In some embodiments, a system may evaluate third-party data for an enterprise (e.g., a potential risk enterprise such as an insurance company), based on information about potential customers received via a first-party data source and additional information about the potential customers from sources other than the enterprise received via a third-party data source. A model factory may provide information about at least one enterprise predictive model, and a third-party data evaluation platform may analyze the additional information to determine an impact on the enterprise predictive model. The third-party data evaluation platform may then output an indication of a result of said analysis to a database of findings (e.g., for use by data scientists).

Abstract: The utility usage of a particular individual occupying a residence may give insight into the individual's current cognitive health and/or to enable provision of various services within the facility for the individual, particularly when monitoring patterns in utility usage over time. To enable accurate and non-invasive utility monitoring, a single-point utility sensor may be secured relative to a utility supply line, and generated signals may be utilized to monitor utility usage and to distinguish between utility fixtures. A centralized computing entity may identify frequency characteristics within the generated data, and may automatically generate one or more machine-learning algorithms to distinguish between utility usage events, without requiring substantial user input.

Abstract: A pre-fabricated mechanical and electrical distribution infrastructure system comprises pre-fabricated panels that are connected together to form an air plenum for air distribution system at a data center location. The pre-fabricated panels include other infrastructure systems pre-assembled to the panels such that installation of the panels to form the air plenum also installs the other infrastructure systems, such as power distribution busways, building management sensors, lighting, etc.