Abstract: A patient monitoring hub can communicate bidirectionally with external devices such as a board-in-cable or a dongle. Medical data can be communicated from the patient monitoring hub to the external devices to cause the external devices to initiate actions. For example, an external device can perform calculations based on data received from the patient monitoring hub, or take other actions (for example, creating a new patient profile, resetting baseline values for algorithms, calibrating algorithms, etc.). The external device can also communicate display characteristics associated with its data to the monitoring hub. The monitoring hub can calculate a set of options for combined layouts corresponding to different external devices or parameters. A display option may be selected for arranging a display screen estate on the monitoring hub.

Abstract: A portable steam generator includes a power source in a housing, a water tank in the housing, a heating element in the housing and configured to heat water in the water tank to produce steam using power from the power source, and a track on the housing configured to support the portable steam generator in an installation position and allow manual removal from the installation position. A pre-plumbed integrated bathroom panel includes a plumbing inlet configured to provide water to the panel, a water outlet connected to the plumbing inlet, a steam outlet connected to the plumbing inlet and a heating element, a sanitizing outlet connected to the plumbing inlet and an additive generator, valves for directing water from the plumbing inlet to the at least one water outlet, the at least one steam outlet, and the at least one sanitizing outlet, and a controller configured to operate at least the plurality of valves.

Abstract: Techniques relating to performance-based metrics for evaluating system quality are described. In an example, sensor data associated with an environment within which a vehicle is positioned is received. A performance metric associated with a trajectory, indicative of a performed behavior of the vehicle, can be determined and a correctness metric can be determined based at least in part on the performance metric. The correctness metric can represent a correctness of the performed behavior. Modification(s) to component(s) and/or system(s), or portions thereof, of the vehicle can be affected based at least in part on the correctness metric.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: A system, for example, a document management system stores documents and manages workflows associated with documents. The document management system allows discovery of templates based on explicit searches performed by users or automatic searches performed based on a context. The document management system allows generating new document templates based on selected versions of document component templates. The generated document template may be stored as a new version. The document management system instantiates documents based on templates by predicting values of variables used in the template based on various factors that describe the context in which the template is being used. The values used for instantiating variables may be generated using machine learning models that may be trained using historical data stored in the document management system.

Abstract: A method of filtration in a process vessel using a treated filter media which has been treated with a conditioner for improved filtration of contaminants is provided. The treated filter media can be used in process vessels for refining, petrochemical, and chemical plants to treat process streams. The conditioner can be the same material as what is expected to be captured during the fouling process. In other words, the conditioner that is added to the treated filter media can be the same material as the contaminant in the fluid stream to be treated. This allows for chemical compatibility with an existing process fluid stream. This also allows for the natural continuation of the filtration process.

Abstract: A system, for example, a document management system stores documents and manages workflows associated with documents. The document management system allows discovery of templates based on explicit searches performed by users or automatic searches performed based on a context. The document management system allows generating new document templates based on selected versions of document component templates. The generated document template may be stored as a new version. The document management system instantiates documents based on templates by predicting values of variables used in the template based on various factors that describe the context in which the template is being used. The values used for instantiating variables may be generated using machine learning models that may be trained using historical data stored in the document management system.

Abstract: A system, for example, a document management system stores documents and manages workflows associated with documents. The document management system allows discovery of templates based on explicit searches performed by users or automatic searches performed based on a context. The document management system allows generating new document templates based on selected versions of document component templates. The generated document template may be stored as a new version. The document management system instantiates documents based on templates by predicting values of variables used in the template based on various factors that describe the context in which the template is being used. The values used for instantiating variables may be generated using machine learning models that may be trained using historical data stored in the document management system.

Abstract: An implantable device for controlling electrical conditions of body tissue. A feedback sense electrode and a compensation electrode are positioned proximal to the tissue to make electrical contact with the tissue. A feedback amplifier is referenced to ground, and takes as an input a feedback signal from the feedback sense electrode. The output of the feedback amplifier is connected to the compensation electrode. The feedback amplifier thus drives the neural tissue via the compensation electrode in a feedback arrangement which seeks to drive the feedback signal to ground, or other desired electrical value.

Abstract: An implantable device for estimating neural recruitment arising from a stimulus, has a plurality of electrodes. A stimulus source provides stimuli to be delivered from the electrodes to neural tissue. Measurement circuitry obtains a measurement of a neural signal sensed at the electrodes. A control unit is configured to control application of a selected stimulus to neural tissue using the stimulus electrodes; and after the selected neural stimulus, apply a probe stimulus having a short pulse width. A remnant neural response evoked by the probe stimulus is measured; and the control unit estimates from the remnant neural response a neural recruitment caused by the selected neural stimulus.

Abstract: Curable compounds, hydrogels, build materials, and methods of 3D printing are described herein. In some embodiments, a build material for 3D printing described herein comprises one or more compounds having the structure(s) of Formula (I) and/or Formula (II) herein. Such a build material may also comprise an additional acrylate component and water.

Abstract: A system and method is disclosed for performing diagnostics on patient devices (720). The patient devices (720) may include respiratory therapy devices that operate in accordance with instruction sets, such as software or firmware. A server (710) may maintain a database of diagnostic data (718) indicating faults in one or more of a plurality of patient devices (720). The server (710) may transmit this diagnostic data (718) to one or more computing devices (760), including identification of faults that have occurred. The server (710) may also transmit service data to the plurality of patient devices (720) in order to address the identified faults.

Abstract: A reference to a digital item is stored as a digital card. The digital card can also be contained in, and/or refer to, other digital cards. The digital card can also include properties or attributes that may be added from the digital item that is being referred to. The digital card can be tagged with a tag that may also be applied to other digital cards. The digital card can be stored in a data pod within a de-centralized data storage system architecture so the tag is surfaced along with the digital card in different contexts.

Abstract: Methods and apparatuses for clock signal phase measurement and control are described. In one example, a clock signal phase measurement system includes a reference clock signal line to provide a reference clock signal, a delay line to provide an output clock signal, and a wild clock. The clock signal phase measurement system includes a phase sensor configured to randomly and simultaneously sample the reference clock signal and the output clock signal utilizing the wild clock to obtain a phase data. The phase sensor is further configured to measure from the phase data a phase difference between the reference clock signal and the output clock signal.

Abstract: Solid state light emitting devices include at least one LED chip with a light-altering material arranged over an entire upper surface thereof, with lateral edges of the LED chip device of lumiphoric material, and at least one of a fill material layer contacting lateral surfaces of the LED chip or a scattering material layer contacting lateral surfaces of a light-altering material when the light-altering material is a lumiphoric material. A method for fabricating a solid state light emitting device comprises applying a fill material layer to contact lateral surfaces of a LED chip, adhering a sealing material template over the fill material, and applying a light-altering material through a window in the template to an upper surface of the LED chip, followed by removal of the template, optionally preceded by impingement of UV emissions to reduce adhesive tack and promote release of the template.

Abstract: A patient monitoring hub can communicate bidirectionally with external devices such as a board-in-cable or a dongle. Medical data can be communicated from the patient monitoring hub to the external devices to cause the external devices to initiate actions. For example, an external device can perform calculations based on data received from the patient monitoring hub, or take other actions (for example, creating a new patient profile, resetting baseline values for algorithms, calibrating algorithms, etc.). The external device can also communicate display characteristics associated with its data to the monitoring hub. The monitoring hub can calculate a set of options for combined layouts corresponding to different external devices or parameters. A display option may be selected for arranging a display screen estate on the monitoring hub.

Abstract: LED chips and related fabrication methods are disclosed. A LED chip includes an active layer arranged on or over a light-transmissive substrate having a light extraction surface. The light extraction surface comprises a microtextured etched surface having a non-repeating, irregular textural pattern (e.g., with an average feature depth in a range of from 120 nm to 400 nm, and preferably free of any plurality of equally sized, shaped, and spaced textural features). The microtextured etched surface may be formed by applying a micromask having first and second solid materials of different etching rates over the light extraction surface, and exposing the micromask to an etchant (e.g., via reactive ion etching) to form a microtextured etched surface having a non-repeating, irregular textural pattern. Lumiphoric material may be applied over the microtextured surface.

Abstract: A method for processing a neural measurement obtained in the presence of artifact, in order to detect whether a neural response is present in the neural measurement. A neural measurement is obtained from one or more sense electrodes. The neural measurement is correlated against a filter template, the filter template comprising at least three half cycles of an alternating waveform, amplitude modulated by a window. From an output of the correlating, it is determined whether a neural response is present in the neural measurement.

Abstract: Recording evoked neural responses comprises delivering a stimulus from one or more stimulus electrodes to a neural pathway in order to give rise to an evoked compound action potential (ECAP) on the neural pathway. And, recording with measurement circuitry, during delivery of at least part of the stimulus, a neural compound action potential signal sensed at one or more sense electrodes. And, processing the recording of the neural compound action potential signal to determine at least one characteristic of the ECAP. At least one characteristic of the stimulus is then defined based on the determined at least one characteristic of the ECAP.

Abstract: A patient monitoring system includes a physiological sensor to sense light after it has passed through tissue of a patient and generate a signal indicative a physiological parameters in response to the sensed light, and a patient monitoring device in communication with the physiological sensor to receive the signal and determine measurements of the physiological parameters from the received signal. The patient monitoring device includes a processor and memory having multiple system images. The patient monitoring device downloads an image upgrade to one system image that the not latest used or tested system image. The patient monitoring device boots the processor from the system image that includes the image upgrade. If the upgraded system image fails, the patient monitoring device boots the processor from another system image of the multiple system images. The patient monitoring device repairs the failed system image.