Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

Abstract: A sealing system for a pump having a plunger includes a housing having an internal chamber adapted to receive a portion of the plunger. Primary and secondary seals are located within the internal chamber and adapted to sealingly engage the plunger. The primary seal communicates with the fluid being pumped. A barrier fluid chamber contains a barrier fluid in contact with the primary seal and the secondary seal. A pressure referencing device has an inlet port in communication with the pumped fluid and an outlet port providing fluid at a pressure magnitude equal to a peak pressure of the pumped fluid. A pressurizing device is in communication with the fluid at the peak pressure and the barrier fluid to maintain the barrier fluid pressure at a magnitude greater than the peak pressure of the pumped fluid such that the pumped fluid is restricted from leaking past the primary seal.

Abstract: There is disclosed a method and controller for controlling an information flow in a data transmission system including receiving a plurality of data packets having a received packet length and at a received sample rate. The method and controller also includes determining a configured packet length for each data packet based on a configured service rate for each data packet. The method and controller may also include scheduling each data packet in accordance with a respective configured packet length.

Abstract: An embodiment of the present invention includes a technique to calibrate receiver and transmitter in a communication system. N digitized samples I(n) and Q(n) are stored. The N digitized samples represent in-phase and quadrature (I-Q) components, respectively, of a down-converted signal from a receiver. The I-Q components are generated from a quadrature demodulator or modulator having I-Q imbalance. Phase and gain adjustment constants are computed from the N digitized samples to compensate for the I-Q imbalance using a closed form solution. Another embodiment of the present invention includes a technique to calibrate a transceiver in a communication system without using a calibrated reference receiver. A first test signal at a first frequency is injected to a transmitter having a quadrature modulator with I-Q imbalance. The quadrature modulator has a carrier frequency. The transmitter generates a transmitter signal.

Abstract: The invention relates to novel binding domain-immunoglobulin fusion proteins that feature a binding domain for a cognate structure such as an antigen, a counterreceptor or the like, a wild-type IgG, IGA or IgE hinge-acting region, i.e., IgE CH2, region polypeptide or a mutant IgGI hinge region polypeptide having either zero, one or two cysteine residues, and immunoglobulin CH2 and CH3 domains, and that are capable of ADCC and/or CDC while occurring predominantly as polypeptides that are compromised in their ability to form disulfide-linked multimers. The fusion proteins can be recombinantly produced at high expression levels. Also provided are related compositions and methods, including cell surface forms of the fusion proteins and immunotherapeutic applications of the fusion proteins and of polynucleotides encoding such fusion proteins.

Abstract: The display panel has an outer surface to which a sign may be attached and an inner surface having a fastener composed of resiliently deformable material. An end of the fastener is separated from the display panel by a slit which is adapted to receive an outer plate of a conventional door handle The outer plate is held in the slit by the resiliently deformable composition of the fastener. The plate may however be removed from the slit by the application of a force opposed to the bias of the resilient material in order to widen the slit.

Abstract: One or more databases for use in computer program application support and maintenance. An inventory of computer program applications (“application inventory”) is arranged in a multilevel hierarchy having descending levels. Line of business level, application level and technical module level. A support and maintenance work authorization and authorized workgroup are set at the line of business level, and requests for work are set at the application level and below. Automatically relates business functions to computer programs to determine performance of applications within business functions. The databases also include timesheets, each timesheet having time data recorded by a skilled person in a workgroup for work on a ticket. Computer system and methods utilizing the databases are also provided.

Abstract: Methods, apparatus, and computer-readable media including computer-readable components for the localization of data included in software programs are described. The computer-readable components comprise data elements defined by a software data schema; a property repository data element for storing a plurality of data properties about the data elements; and an owned comment data element comprising information about the localization of the data included in software programs and an owner with permission to create, access, and manipulate the owned comment data element.

Abstract: The present invention generally provides methods for B-cell reduction in an individual using CD37-specific binding molecules. In particular, the invention provides methods for B-cell reduction using CD37-specific binding molecules alone, or a combination of CD37-specific binding molecules and CD20-specific binding molecules, in some instances a synergistic combination. The invention further provides materials and methods for treatment of diseases involving aberrant B-cell activity. In addition, the invention provides humanized CD37-specific binding molecules.

Abstract: Methods, apparatus, and computer-readable media employing computer-readable components for localization of data included in software programs are described. The computer-readable components comprise data elements defined based on a software data schema; and an owned comment data element comprising information about the localization of the data included in the software programs and an associated owner with permission to create, access, and manipulate the owned comment data element. The owned comment data element is included in other data elements. The owned comment data element may also be included in a list of owned comment elements comprising at least one owned comment data element.

Abstract: This invention relates to a feed roller apparatus, comprising; a feed roller centerpiece having first and second ends, a shaft operatively connected to the first and second ends of the centerpiece, and a textured metallic layer located substantially adjacent to an outer surface of the centerpiece.

Abstract: Apparatus 10 discloses a handle 32 for manipulating the device and an extending rule portion 18 having a series of markings or measurements 26 embossed along its edge serving as a base of spacing measurement for a pivotally mounted swing arm 22 and a slide arm 24 perpendicularly attached thereto that may be adjusted to a desired distance. After a desired distance is set the swing arm 22 serves to maintain spacing and parallelism by having a bubble level 36 fabricated into each of its ends to test if the materials held flush are level. After correct measurements are made the apparatus 10 may then be used as a gauging tool for the quick and ready spacing and setting of materials afterwards.

Abstract: The present invention provides a tank having a bottom portion that is adapted to be received by a truck platform between the wheel wells so that the tank can be easily moved past the wheel wells. In addition, the tank preferably has a first top panel that is adapted to receive the pump, engine, hose and/or reel. Since the foregoing are mounted onto the tank, the useable space on the platform is increased. Further, the first top panel is preferably positioned near the edge of the platform so that the sprayer system controls are accessible and convenient for a user.

Abstract: A system and method providing dynamic detection and correction of data corrupted by external interference in wireless communications network includes an interference detection unit and correction unit. Detection unit detects impact on video signals based on measuring condition of predetermined portion of video signals. Correction unit corrects the interference by selecting previously stored data to replace corrupted video data.

Abstract: A data reception unit for receiving a plurality of data streams over a data channel, the data streams being received as amounts of data and each amount of data comprising a data portion including data from a data stream and an identity portion identifying that data stream, the data reception unit comprising: a data stream memory comprising a plurality of data stream storage areas, each for storing data from a respective one of a set of the data streams, and an escape buffer; a first storage information memory for holding first storage information for facilitating storage in the respective data stream storage area of data from the set of the data streams; and a data storage controller for, for each received amount of data, receiving the identity portion of the amount of data and performing a storage operation comprising: accessing the first storage information memory; and if the first storage information memory holds first storage information for the data stream identified by the identity portion, storing the

Abstract: The invention relates to novel binding domain-immunoglobulin fusion proteins that feature a binding domain for a cognate structure such as an antigen, a counterreceptor or the like, a wild-type IgG1, IGA or IgE hinge-acting region, i.e., IgE CH2, region polypeptide or a mutant IgG1 hinge region polypeptide having either zero, one or two cysteine residues, and immunoglobulin CH2 and CH3 domains, and that are capable of ADCC and/or CDC while occurring predominantly as polypeptides that are compromised in their ability to form disulfide-linked multimers. The fusion proteins can be recombinantly produced at high expression levels. Also provided are related compositions and methods, including cell surface forms of the fusion proteins and immunotherapeutic applications of the fusion proteins and of polynucleotides encoding such fusion proteins.

Abstract: A torque transfer assembly having a first rotatable element with a first flange, a second rotatable element with a second flange, and an alignment assembly establishing a single coupled orientation for the first and second rotatable elements. First and second imbalance vectors, corresponding to the first and second rotatable elements respectively, each include a magnitude and direction relative to the reference axis which are in balancing alignment when the rotatable elements are in the coupled orientation.

Abstract: A system which marries a tethered, digital bus with image broadcasting to allow multiple, low-cost cameras to communicate with a host. This is done by using an external receiver on a tethered bus, and by putting much of the processing circuitry in the receiver, rather than the camera. The broadcasting can be either a NTSC/PAL type of analog broadcasting or a digital broadcasting technique. The camera can be made with low cost, readily available NTSC/PAL, other analog video components, or with readily available digital telephone components. The external receiver unit of the present invention does all the necessary data processing and compression to fit the available bandwidth of the bus to which it is communicating, and provides for a low cost and extensible method of inputting digital image data into a personal computer (PC) or other host.

Abstract: A pharmaceutical composition comprising ciprofloxacin, cyclodextrin, and a hydroxy acid is described. The composition may be an aqueous composition, with such aqueous compositions preferably having a pH between 5 and 7. In some preferred embodiments, the composition further comprises a soluble polymer.

Abstract: A data reception unit for receiving a plurality of data streams over a data channel. The data streams are received as amounts of data, each amount of data comprising a data portion including data from a data stream and an identity portion identifying that data stream. The data reception unit comprises a data stream memory comprising a plurality of data stream storage areas and a buffer, a first storage information memory for holding first storage information, a processing unit, and a data storage controller. The data storage controller, for each received amount of data, receives the identity portion of the amount of data and performs a storage operation based on the identity portion.