Patents by Inventor Peter A. Welling

Peter A. Welling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Continuous-read assay for the detection of de novo HCV RNA polymerase activity
    Publication number: 20040209283
    Abstract: The invention provides a method for detecting RNA polymerase activity in a continuous-read manner. Specifically, the invention provides a method for detecting the de novo polymerase activity of the Hepatitis C virus (HCV) polymerase, NS5B, in a continuous-read manner. The invention also provides a method of screening for modulators of RNA polymerase activity. More specifically, the invention provides a method of screening for modulators of HCV NS5B activity.
    Type: Application
    Filed: November 13, 2003
    Publication date: October 21, 2004
    Applicant: Pfizer Inc.
    Inventors: Yoshihiko Yagi, Michael P. Sheets, Peter A. Wells, John A. Shelly, Roger A. Poorman, Dennis E. Epps, Aric G. Morgan
  • Elongation factor P (EFP) and assays and antimicrobial treatments related to the same
    Patent number: 6511813
    Abstract: Disclosed are novel methods of using elongation factor p (efp) and related constituents of ribosomal complexes which comprise efp, the 50S ribosomal subunit, the 30S ribosomal subunit, the 70S initiation complex, and related proteins, cofactors and enzymes. Methods of identifying compounds which modulate prokaryotic elongation factor p and modify cell function are described. Both in vitro and in vivo methods for identifying compounds which modulate such constituents and affect cell function are described. Such identified compounds, including various antibiotics, which specifically affect cell growth, methods of treating various disorders with such compounds, and antiseptics containing such compounds are described. The present invention is also directed to methods and compounds that modulate prokaryotic elongation factor p.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: January 28, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Keith R. Marotti, Roger A. Poorman, Peter A. Wells, Dean L. Shinabarger
  • Waveform modulation system
    Patent number: 4685114
    Abstract: An improved waveform modulation system for converting an input value having a known radix and a predetermined maximum number of digits into a waveform having successive intervals, by separating the input value into a least significant value portion occupying a preselected number of least significant digits and into a most significant value portion occupying a preselected number of most significant digits. For each interval, the system combines the least significant value portion with a residual value to produce a carry for that interval and a successive residual value. The system iteratively generates a waveform with successive intervals each having a duration defined by the preselected number of most significant digits and an underlying pulse width defined by the most significant value portion and modified according to the carry for that interval.
    Type: Grant
    Filed: February 27, 1986
    Date of Patent: August 4, 1987
    Assignee: The Charles Stark Draper Laboratory, Inc.
    Inventor: Peter A. Welling