Patents by Inventor Peter B. Barker

Peter B. Barker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for blood brain permeability imaging (BBPI) using dynamic susceptibility contrast magnetic resonance imaging
    Patent number: 10076263
    Abstract: A system and method for generating dynamic susceptibility contrast information from medical imaging data acquired using a magnetic resonance imaging (MRI) system and from a subject having received a dose of a contrast agent. A plurality of images are acquired of the subject. Using the images, an arrival time correction (ATC) is determined that includes a value for at least one of a time shift variable, a time stretch variable, and an amplitude scale variable. The ATC is applied to a model of dynamic susceptibility contrast that relates a measure of signal change over time with a correction term to dynamic susceptibility contrast information to create a corrected model of dynamic susceptibility contrast including the ATC. At least one contrast agent concentration curve is generated from the plurality of images using the corrected model.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: September 18, 2018
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Richard Leigh, Peter B. Barker
  • SYSTEM AND METHOD FOR BLOOD BRAIN PERMEABILITY IMAGING (BBPI) USING DYNAMIC SUSCEPTIBILITY CONTRAST MAGNETIC RESONANCE IMAGING
    Publication number: 20150065865
    Abstract: A system and method for generating dynamic susceptibility contrast information from medical imaging data acquired using a magnetic resonance imaging (MRI) system and from a subject having received a dose of a contrast agent. A plurality of images are acquired of the subject. Using the images, an arrival time correction (ATC) is determined that includes a value for at least one of a time shift variable, a time stretch variable, and an amplitude scale variable. The ATC is applied to a model of dynamic susceptibility contrast that relates a measure of signal change over time with a correction term to dynamic susceptibility contrast information to create a corrected model of dynamic susceptibility contrast including the ATC. At least one contrast agent concentration curve is generated from the plurality of images using the corrected model.
    Type: Application
    Filed: August 30, 2013
    Publication date: March 5, 2015
    Inventors: Richard Leigh, Peter B. Barker