Abstract: Technologies are provided for alignment of spatial transcriptome slides of biological tissue. The alignment of images and the coordinates of spots within transcriptome profiles of the biological tissue can utilize an alignment model that can be machine-learned and can receive both a displaced image to be aligned and a reference image as inputs. The alignment model may learn a diffeomorphic transformation between those images. Such a transformation can be readily applied to the alignment of the displaced image and to the alignment of the displaced coordinates of spots within the transcriptome profiles of transcriptome. In some cases, transcriptome data can be analyzed and cast in an image-like format, and can then be utilized as supplementary input to the alignment model. The alignment model can be trained in a tissue agnostic manner, such as by using synthetic images.

Abstract: Methods of assessing the suitability of a fluorochrome panel for use in a flow cytometric protocol analyzing a biological sample are provided. Methods of interest include, with a processor, receiving an initial fluorochrome panel, a plurality of population identifiers each referring to a particle population, and an instrument identifier. Methods additionally include, creating a set of population-marker pairs, generating a set of separability metrics each predicting a measure of statistical distance between particle populations in flow cytometer data space, aggregating the set of separability metrics into a panel score, and evaluating the panel score. Systems and non-transitory computer readable storage media for assessing the suitability of a fluorochrome panel for use in a flow cytometric protocol analyzing a biological sample are also provided.

Abstract: A system for real-time video streaming for a vehicle includes a camera system configured to capture videos of an environment surrounding the vehicle. The system also includes a vehicle communication system configured to communicate with a remote server and a vehicle controller in electrical communication with the camera system and the vehicle communication system. The vehicle controller is programmed to determine a system enablement state. The vehicle controller is further programmed to determine a camera system configuration in response to determining that the system enablement state is a system enabled state. The vehicle controller is further programmed to capture at least one video frame using the camera system based at least in part on the camera system configuration. The vehicle controller is further programmed to transmit the at least one video frame to the remote server using the vehicle communication system.

Abstract: An isocyanate-reactive composition comprises (A) a polyol, (B) a polysiloxane, and (C) a polyether alcohol compound. A composition for preparing a foam comprises the isocyanate-reactive composition, (D) a polyisocyanate, (E) a catalyst, and (F) a blowing agent. The composition forms a foam upon at least components (A) and (D) reacting in the presence of components (E) and (F).

Abstract: A dispenser system has a base. A rear mount is formed on the base and the rear mount is configured to attach to a wall. A front cover is configured to fit over the base. The modular socket is formed in the base. The pump housing is configured to fit in the modular socket as a module. The pump is mounted inside the pump housing. A liquid container bracket retains a bracket socket. The liquid container bracket is mounted to the pump housing. A nozzle bracket retains a nozzle. The nozzle bracket is mounted to the pump housing. The nozzle is connected to the pump by an exit tubing. A liquid container removably connects to the bracket socket. Liquid in the liquid container flows through the bracket socket and then to an inlet tubing. The inlet tubing is then connected to the pump.

Abstract: A counter mount fluid dispenser has a spout having an opening for dispensing a fluid. The connection shaft extends downwardly from the spout. A swivel base is mounted to the connection shaft. The swivel base swivels relative to the connection shaft. The swivel base includes a mounting shaft having a mounting shaft nut that is configured with the spout to engage a countertop by clamping force. The mounting shaft nut has a mounting shaft nut lower extension. A mounting shaft nut external thread is formed on an external surface of the mounting shaft nut lower extension. A mounting shaft nut retainer is threaded to the mounting shaft nut lower extension.

Abstract: A counter mount soap dispenser includes a spout having an opening for dispensing soap. A connection shaft extends downwardly from the spout. A swivel base mounted to the connection shaft swivels relative to the connection shaft to allow easy connection. Tubing connected to the swivel base are flexible and flex with the rotation of the swivel base. A first tube extension and a second tube extension extend from the swivel base. A extends barrel extending upwardly from a soap reservoir. The barrel has a barrel socket that receives the connection shaft. The barrel socket defines a barrel inside sidewall.

Abstract: A countertop foam dispenser has a spout made of a spout extension front housing and a spout extension rear housing. The spout includes a spout nozzle with a spout opening. A spout mounting shaft is mounted to the spout at a mounting shaft bracket. A mixer pump housing has a spout retainer latch. The mixer pump housing houses a mixer pump. The mixer pump includes a motor. A retainer notch is formed on the lower portion of the spout. The retainer notch is configured to engage the spout retainer latch. A bottle contains liquid soap. The bottle has a connection to the mixer pump housing.

Abstract: A countertop foam dispenser has a spout made of a spout extension front housing and a spout extension rear housing. The spout includes a spout nozzle with a spout opening. A spout mounting shaft is mounted to the spout at a mounting shaft bracket. A mixer pump housing has a spout retainer latch. The mixer pump housing houses a mixer pump. The mixer pump includes a motor. A retainer notch is formed on the lower portion of the spout. The retainer notch is configured to engage the spout retainer latch. A bottle contains liquid soap. The bottle has a connection to the mixer pump housing.

Abstract: A countertop foam dispenser has a spout made of a spout extension front housing and a spout extension rear housing. The spout includes a spout nozzle with a spout opening. A spout mounting shaft is mounted to the spout at a mounting shaft bracket. A mixer pump housing has a spout retainer latch. The mixer pump housing houses a mixer pump. The mixer pump includes a motor. A retainer notch is formed on the lower portion of the spout. The retainer notch is configured to engage the spout retainer latch. A bottle contains liquid soap. The bottle has a connection to the mixer pump housing.

Abstract: A countertop foam dispenser has a spout made of a spout extension front housing and a spout extension rear housing. The spout includes a spout nozzle with a spout opening. A spout mounting shaft is mounted to the spout at a mounting shaft bracket. A mixer pump housing has a spout retainer latch. The mixer pump housing houses a mixer pump. The mixer pump includes a motor. A retainer notch is formed on the lower portion of the spout. The retainer notch is configured to engage the spout retainer latch. A bottle contains liquid soap. The bottle has a connection to the mixer pump housing.

Abstract: The present invention provides methods of treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.

Abstract: A soap dispenser includes a wall mount housing and a housing cover mounted to the wall mount housing. A compression module mechanism has an upper compression module and a lower compression module mounted in a sliding relationship. The compression module mechanism is mounted to the wall mount housing. A cartridge has a tank filled with liquid soap. The cartridge includes a neck with a neck groove and a nozzle. The cartridge includes a soap pump that pumps soap through the nozzle. A neck retainer has a neck retainer guide. The neck retainer guide is configured to fit to the neck groove. A soap piston is mounted to the neck in a telescopic sliding relationship. The soap piston extends beyond the neck groove. The soap piston terminates at a soap nozzle.

Abstract: The present invention provides methods of treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.

Abstract: A foam generator includes a container having a liquid. The container includes a container neck. A bubble generator is mounted to the container. The bubble generator has a liquid piston and an air piston that are mechanically connected together to simultaneously dispense the liquid and a flow of air. The liquid piston extends into the container as a bubble generator input stem. The liquid is received into the bubble generator input stem at a liquid piston intake of the bubble generator input stem. The air piston and the liquid piston feed both air and liquid to a mixing chamber that provides both air and liquid to a pair of mixing screens mounted on a bubble generator output stem. The bubble generator output stem is oriented below the bubble generator input stem. An inverted straw cover fits over the liquid piston intake of the input stem.

Abstract: The present invention provides methods of treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.

Abstract: A foam generator includes a container having a liquid. The container includes a container neck. A bubble generator is mounted to the container. The bubble generator has a liquid piston and an air piston that are mechanically connected together to simultaneously dispense the liquid and a flow of air. The liquid piston extends into the container as a bubble generator input stem. The liquid is received into the bubble generator input stem at a liquid piston intake of the bubble generator input stem. The air piston and the liquid piston feed both air and liquid to a mixing chamber that provides both air and liquid to a pair of mixing screens mounted on a bubble generator output stem. The bubble generator output stem is oriented below the bubble generator input stem. An inverted straw cover fits over the liquid piston intake of the input stem.

Abstract: The present invention provides methods of treating various disorders associated with mitochondrial dysfunction, including but not limited to metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, and diseases of aging.