Patents by Inventor Peter C. Dowling

Peter C. Dowling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
    Patent number: 11559565
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 24, 2023
    Assignees: United States Government As Represented By The Department of Veterans Affairs, Rutgers, The State University of New Jersey
    Inventors: Peter C. Dowling, Bo Wang, Rui Rong Yuan, Wei Lu
  • Methods For Treating Inflammatory Disorders and Traumatic Brain Injury Using Stabilized Non-Hematopoietic EPO Short Peptides
    Publication number: 20200376079
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Application
    Filed: June 5, 2020
    Publication date: December 3, 2020
    Inventors: Peter C. Dowling, Bo Wang, Rui Rong Yuan, Wei Lu
  • METHODS FOR TREATING INFLAMMATORY DISORDERS AND TRAUMATIC BRAIN INJURY USING STABILIZED NON-HEMATOPOIETIC EPO SHORT PEPTIDES
    Publication number: 20180303903
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Application
    Filed: July 2, 2018
    Publication date: October 25, 2018
    Inventor: Peter C. Dowling
  • Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
    Patent number: 10047132
    Abstract: The present disclosure provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: August 14, 2018
    Inventor: Peter C. Dowling
  • ERYTHROPOIETIN-DERIVED SHORT PEPTIDE AND ITS MIMICS AS IMMUNO/INFLAMMATORY MODULATORS
    Publication number: 20180016315
    Abstract: The present disclosure provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Application
    Filed: September 13, 2017
    Publication date: January 18, 2018
    Inventor: Peter C. Dowling
  • Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
    Patent number: 9765128
    Abstract: The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: September 19, 2017
    Inventor: Peter C. Dowling
  • USE OF EPO-DERIVED PEPTIDE FRAGMENTS FOR THE TREATMENT OF INFLAMMATORY DISEASES
    Publication number: 20170137483
    Abstract: The described invention provides compositions having EPO-derived peptides, and methods and kits for administering the EPO-derived peptide to a subject suffering from a neurodegenerative disease or an inflammatory disease of the brain or spinal cord. The EPO-derived peptide delays the onset and/or progression of a neurodegenerative disease, limits cognitive impairment in, and prolongs the survival of, subjects suffering from a neurodegenerative disease or an inflammatory disease of the brain or spinal cord.
    Type: Application
    Filed: January 23, 2017
    Publication date: May 18, 2017
    Inventor: Peter C. Dowling
  • Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
    Patent number: 9585932
    Abstract: The described invention provides methods and kits for administering an EPO-derived peptide to a subject suffering from a neurodegenerative disease. The EPO-derived peptide delays the onset and/or progression of a neurodegenerative disease, limits cognitive impairment in, and prolongs the survival of, subjects suffering from a neurodegenerative disease.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: March 7, 2017
    Inventor: Peter C. Dowling
  • USE OF EPO-DERIVED PEPTIDE FRAGMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20160271206
    Abstract: The described invention provides methods and kits for administering an EPO-derived peptide to a subject suffering from a neurodegenerative disease. The EPO-derived peptide delays the onset and/or progression of a neurodegenerative disease, limits cognitive impairment in, and prolongs the survival of, subjects suffering from a neurodegenerative disease.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 22, 2016
    Inventors: Wei Lu, Peter C. Dowling, Rong Yuan
  • Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
    Patent number: 9345745
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: May 24, 2016
    Inventors: Bo Wang, Rui Rong Yuan, Wei Lu, Peter C. Dowling
  • USE OF EPO-DERIVED PEPTIDE FRAGMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
    Publication number: 20140256629
    Abstract: The described invention provides methods and kits for administering an EPO-derived peptide to a subject suffering from a neurodegenerative disease. The EPO-derived peptide delays the onset and/or progression of a neurodegenerative disease, limits cognitive impairment in, and prolongs the survival of, subjects suffering from a neurodegenerative disease.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 11, 2014
    Inventors: Wei Lu, Rui Rong, Peter C. Dowling
  • METHODS FOR TREATING INFLAMMATORY DISORDERS AND TRAUMATIC BRAIN INJURY USING STABILIZED NON-HEMATOPOIETIC EPO SHORT PEPTIDES
    Publication number: 20110190217
    Abstract: The described invention provides methods for treating an inflammatory brain disease, disorder or condition and for treating a traumatic brain injury having an inflammatory component in a subject in need thereof using isolated erythropoietin (EPO)-derived oligopeptides.
    Type: Application
    Filed: March 28, 2011
    Publication date: August 4, 2011
    Inventors: Bo Wang, Rui Rong Yuan, Wei Lu, Peter C. Dowling