Patents by Inventor Peter C. Knüppel

Peter C. Knüppel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 3-substituted 4-cyano-pyrrole compounds
    Patent number: 6204397
    Abstract: A process for the preparation of 3-substituted 4-cyano-pyrrole compounds of the formula (I) in which Ar has the meaning given in the description, by reaction in a 1st stage of bromides (II) Ar—Br  (II) with acrylonitrile in the presence of a solvent and a suitable reaction auxiliary to give acrylonitrile derivatives (III) Ar—CH═CH—CN  (III) and in a 2nd stage with a phenylsulphonylmethyl isocyanide (IV) Ph—SO2—CH2—CN  (IV) in the presence of a solvent and optionally in the presence of a suitable reaction auxiliary, characterised in that the the 1st stage is carried out in the presence of a palladium catalyst and the 2nd stage in the presence of a 1.2- to 1.8-fold molar excess of alkali metal alcoholate or alkali metal hydroxide.
    Type: Grant
    Filed: July 1, 1993
    Date of Patent: March 20, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Peter C. Knüppel, Reinhard Lantzsch, Klaus Jelich, Peter Andres, Albrecht Marhold