Patents by Inventor Peter C. Michels

Peter C. Michels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220213428
    Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.
    Type: Application
    Filed: March 21, 2022
    Publication date: July 7, 2022
    Applicant: TEEWINOT LIFE SCIENCES CORPORATION
    Inventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. MICHELS, John D. RABENSTEIN, C. Seth PEARSON, Geoffrey M. FOX
  • Patent number: 11319525
    Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: May 3, 2022
    Assignee: TEEWINOT LIFE SCIENCES CORPORATION
    Inventors: Richard Peet, Malcolm J. Kavarana, Mingyang Sun, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
  • Publication number: 20220025424
    Abstract: The present disclosure relates to compositions and methods for producing stereoisomerically pure aminocyclopropanes.
    Type: Application
    Filed: August 16, 2017
    Publication date: January 27, 2022
    Inventors: Amy E. TAPPER, Cassandra CELATKA, Arthur Glenn ROMERO, John M. MCCALL, Toni CHANCELLOR, He ZHAO, Betina BIOLATTO, Jian-Xie CHEN, Elisabeth C.A. BROT, Peter C. MICHELS, Venkat K. CHARI, Ian C. COTTERILL
  • Publication number: 20190382708
    Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.
    Type: Application
    Filed: June 26, 2019
    Publication date: December 19, 2019
    Inventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
  • Patent number: 10336978
    Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: July 2, 2019
    Assignee: TEEWINOT TECHNOLOGIES LIMITED
    Inventors: Richard Peet, Malcolm J. Kavarana, Mingyang Sun, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
  • Publication number: 20180346866
    Abstract: The disclosure provides systems and methods for producing a cannabinoid product, which comprises contacting a cannabinoid precursor in a first phase with a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible. The disclosure also provides a composition comprising the cannabinoid precursor in a first phase and a cannabinoid synthase in a second phase, wherein the first phase and the second phase are substantially immiscible or immiscible.
    Type: Application
    Filed: May 10, 2018
    Publication date: December 6, 2018
    Applicant: TEEWINOT TECHNOLOGIES LIMITED
    Inventors: Richard PEET, Malcolm J. KAVARANA, Mingyang SUN, Peter C. Michels, John D. Rabenstein, C. Seth Pearson, Geoffrey M. Fox
  • Publication number: 20140179624
    Abstract: Disclosed herein are novel cytoprotective derivatives of avicin D, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives and compositions thereof, including for the treatment of cancer, are also provided.
    Type: Application
    Filed: December 20, 2013
    Publication date: June 26, 2014
    Applicant: Research Development Foundation
    Inventors: Jordan GUTTERMAN, Valsala HARIDAS, Peter C. MICHELS, Yuri L. KHMELNITSKY, Vadim M. MOZHAEV
  • Patent number: 8754054
    Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: June 17, 2014
    Assignee: Albany Molecular Research, Inc.
    Inventors: Grant J. Carr, David D. Manning, Zhicai Yang, Cheng Guo, Jun-Ho Maeng, Peter C. Michels, Matthew W. Chase
  • Publication number: 20130237490
    Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.
    Type: Application
    Filed: September 17, 2010
    Publication date: September 12, 2013
    Applicant: Albany Molecular Research, Inc.
    Inventors: Grant J. CARR, David D. MANNING, Zhicai YANG, Cheng GUO, Jun-Ho MAENG, John RABENSTEIN, Peter C. MICHELS, Matthew W. CHASE
  • Publication number: 20120010163
    Abstract: The present invention relates to novel therapeutics with antibacterial activity, processes for their preparation, and pharmaceutical, veterinary and nutritional compositions containing them as active ingredients. The present invention also relates to uses of the novel therapeutics, for example, as medicants or food additives in the treatment of bacterial infections or to aid body mass gain in a subject.
    Type: Application
    Filed: September 17, 2010
    Publication date: January 12, 2012
    Applicant: Albany Molecular Research, Inc.
    Inventors: GRANT J. CARR, DAVID D. MANNING, ZHICAL YANG, CHENG GUO, JUN-HO MAENG, JOHN RABENSTEIN, PETER C. MICHELS, MATTHEW W. CHASE
  • Patent number: 7842122
    Abstract: A gas remover apparatus suitable for electrical substation high-voltage transformer load tap changers and similar oil-filled equipment removes potentially hazardous and destructive gases from the air-filled volume above the insulating oil bath in which the load tap changer electrical contacts are immersed. The apparatus applies a continuous supply of nitrogen to the load tap changer, and has an orifice to maintain a slight overpressure over an extreme range of climatic conditions. The substantially continuous venting of nitrogen entrains and expels contaminants such as oxygen, water, and potentially explosive breakdown products from the oil, all of which can degrade the performance of the load tap changer.
    Type: Grant
    Filed: October 31, 2003
    Date of Patent: November 30, 2010
    Assignee: Waukesha Electric Systems Incorporated
    Inventors: Thomas M. Golner, Peter C. Michel
  • Patent number: 7691615
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above in the presence of a microorganism under conditions effective to produce the product compound.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 6, 2010
    Assignee: Albany Molecular Research, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Patent number: 7538084
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: Formula I where A is an amino acid of Formula II: or a pharmaceutically acceptable salt thereof, with R0, R1, B, C, D, E, F, G, H, I, J, and K defined herein.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: May 26, 2009
    Assignee: AMR Technology, Inc.
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Patent number: 7232908
    Abstract: The present invention relates to a process for the production of piperidine derivatives with microorganisms. This is carried out by incubating starting compounds in the presence of a microorganism under conditions effective to produce piperidine derivative products. Suitable microorganisms can be from any one of the genus of Stemphylium, Gliocladium, Bacillus, Botrytis, Cyathus, Rhizopus, Pycniodosphora, Pseudomonas, Helicostylum, Mucor, Gelasinospora, Rhodotorula, Candida, Mycobacterium, and Penicillium. In another aspect of the invention, starting compounds are incubated in the presence of Cunninghamella bainieria under conditions effective to produce piperidine derivative products.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: June 19, 2007
    Assignee: AMR Technology, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Publication number: 20040235716
    Abstract: The compounds of the present invention are represented by the chemical structure found in Formula I: 1 Formula I 1
    Type: Application
    Filed: March 16, 2004
    Publication date: November 25, 2004
    Inventors: Bruce F. Molino, Simon N. Haydar, Zhicai Yang, Peter C. Michels, Michael S. Hemenway, Joseph O. Rich, Yuri Khmelnitsky
  • Patent number: 6613907
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above In the presence of a microorganism under conditions effective to produce the product compound.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: September 2, 2003
    Assignee: AMR Technology, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Patent number: 6568287
    Abstract: An oil sampling system for an electrical power device in which the oil flows through the sampling device in a closed loop with the oil containing apparatus of the electrical power device. Oil is taken in from an active region near the top of the oil containing apparatus and returned to a lower region thereof. This assures that the oil sample is representative of the oil in the system. For the case of a power transformer, the oil flow is by cooling with gravity assistance. For the case of a pumped system, such as a load tap changer, the oil flow is forced. The sampling procedure begins with connecting the sampling device in the closed loop. Oil is then passed through the sampling device until bubble free. The sampling device is then removed for analysis. The procedure does not need a flush operation or a flush container.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: May 27, 2003
    Assignee: Waukesha Electric Systems
    Inventors: Thomas M. Golner, Peter C. Michel
  • Patent number: 6465625
    Abstract: Highly specific biocatalytic reactions have been used to create a population of taxol derivatives.
    Type: Grant
    Filed: June 19, 2000
    Date of Patent: October 15, 2002
    Assignee: Albany Molecular Research, Inc.
    Inventors: Jonathan S. Dordick, Douglas S. Clark, Peter C. Michels, Yuri L. Khmelnitsky
  • Publication number: 20020083781
    Abstract: An oil sampling system for an electrical power device in which the oil flows through the sampling device in a closed loop with the oil containing apparatus of the electrical power device. Oil is taken in from an active region near the top of the oil containing apparatus and returned to a lower region thereof. This assures that the oil sample is representative of the oil in the system. For the case of a power transformer, the oil flow is by cooling with gravity assistance. For the case of a pumped system, such as a load tap changer, the oil flow is forced. The sampling procedure begins with connecting the sampling device in the closed loop. Oil is then passed through the sampling device until bubble free. The sampling device is then removed for analysis. The procedure does not need a flush operation or a flush container.
    Type: Application
    Filed: December 29, 2000
    Publication date: July 4, 2002
    Inventors: Thomas M. Golner, Peter C. Michel
  • Publication number: 20020087003
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: 1
    Type: Application
    Filed: January 4, 2001
    Publication date: July 4, 2002
    Inventors: Peter C. Michels, Eric L. Zirbes