Patents by Inventor Peter C. Ratsep

Peter C. Ratsep has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced relaxivity monomeric and multimeric compounds
    Publication number: 20040131551
    Abstract: Metal chelates capable of exhibiting an immobilized relativity between about 60 and 200 mM−1s−1/metal atom are useful as magnetic resonance imaging agents.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Inventors: Ramachandran S. Ranganathan, Radhakrishna Pillai, Peter C. Ratsep, Rajesh Shukla, Michael F. Tweedle, Xun Zhang
  • Enhanced relaxivity monomeric and multimeric compounds
    Patent number: 6693190
    Abstract: Metal chelates capable of exhibiting an immobilized relativity between about 60 and 200 mM−1s−1/metal atom are useful as magnetic resonance imaging agents. Additionally, a compound which is useful as a metal-chelating ligand has the following formula: wherein Q is a 4- to an 8-membered carbocyclic ring which may be fully or partially saturated; t is an integer from 2 to 16; each R group is independently hydrogen, —OH, —CH2—A, —OCH2CH(OH)CH2—A or a functional group capable of forming a conjugate with a biomolecule, provided that at least two of the R groups are selected from —CH2—A or —OCH2CH(OH)CH2—A; and A is a moiety capable of chelating a metal atom.
    Type: Grant
    Filed: May 11, 1994
    Date of Patent: February 17, 2004
    Assignee: Bracco International B.V.
    Inventors: Ramachandran S. Ranganathan, Radhakrishna Pillai, Peter C. Ratsep, Rajesh Shukla, Michael F. Tweedle, Xun Zhang
  • Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents
    Patent number: 5358704
    Abstract: Novel compounds of the formula ##STR1## and metal chelates of the compounds are useful particularly for MRI of the hepatobiliary system.
    Type: Grant
    Filed: September 30, 1993
    Date of Patent: October 25, 1994
    Assignee: Bristol-Myers Squibb
    Inventors: Jean F. Desreux, Michael F. Tweedle, Peter C. Ratsep, Thomas R. Wagler, Edmund R. Marinelli