Abstract: A cartridge holding unit includes a cartridge container forming an outer surface of the cartridge holding unit and having an inner space, and a cartridge holder forming a tube-shaped holding section arranged in the inner space of the cartridge container, the cartridge holder configured to firmly hold a cartridge in parallel with the cartridge holder and the cartridge holder and the cartridge container are firmly coupled to each other regarding their axial orientations.

Abstract: A dose delivery mechanism includes a housing, a piston rod that acts on a plunger sealing a fluid compartment and moves in an axial direction relative to the housing to deliver a set dose, and a dose setting member that is movable relative to the housing during dose setting. A position of the dose setting member relative to the housing defines the set dose, and in an as-delivered condition the dose setting member is preset to a position that corresponds to a set dose higher than zero.

Abstract: A dose delivery mechanism includes a piston rod and a nut. The piston rod forms an outer thread meshing with an inner thread of the nut, and during dose setting, the nut is rotated relative to the piston rod to advance the nut with respect to the piston rod by a first distance into a distal direction, an actuation member that is movable by a user to effect delivery of a set dose, and a housing. A second threaded connection is configured to cause the actuation member to travel a second distance into the distal direction during dose setting. The actuation member is coupled via the nut to the piston rod during dose delivery to advance the piston rod by the first distance into a proximal direction upon proximal movement of the actuation member by the second distance, and the second distance is less than 1.5 times the first distance.

Abstract: A dose setting mechanism configured to set a desired dose for an injection device, the dose setting mechanism includes a housing, a dose setting knob, a dose setting device and a coupling element. The dose setting knob is configured to set the desired dose by a compulsory guided combined axial and rotational movement of the dose setting knob relative to the housing. Upon drug delivery, the dose setting knob is moved axially relative to the dose setting device or the housing and the coupling element is configured to engage at least one of the dose setting device and the housing to thereby permanently axially lock the dose setting knob to the respective one of the dose setting device and the housing.

Abstract: A set includes a medicament delivery device with a dose delivery activation mechanism that is configured to adjust the medicament delivery device from an inactive state to an active state in which a dose is deliverable, and a cover. The cover is mechanically attached to the medicament delivery device prior to use of the medicament delivery device, and is configured to cover at least a part of the dose delivery activation mechanism so that a user is restrained from prematurely activating the medicament delivery device. The cover is configured to be movable in a distal direction to uncover the part of the dose delivery activation mechanism to activate the medicament delivery device during use of the medicament delivery device.

Abstract: A dose delivery mechanism for a medicament delivery device includes a housing, a piston rod, and an adjusting element. The housing is configured to connect to a medicament container sealed by a plunger. In the assembled state, the dose delivery mechanism is configured to move the piston rod axially in a proximal direction with respect to the housing during dose delivery such that the piston rod exerts an axial force in the proximal direction on the plunger of the medicament container to expel a medicament from the medicament container.

Abstract: A surgical robot arm comprises a base connected to a terminal link via a series of intermediate joints. The terminal link comprises a drive assembly interface comprising drive assembly interface elements. Each drive assembly interface element is configured to: engage an instrument interface element of an instrument interface of a robotic surgical instrument when the surgical robot arm engages the robotic surgical instrument; and move relative to the drive assembly interface across a range of motion so as to, when engaged with the instrument interface element, transfer drive to that instrument interface element. The drive assembly interface elements are arranged across a plane perpendicular to the longitudinal axis of the terminal link such that the robotic surgical instrument is detachable from the surgical robot arm in a detachment direction parallel to the plane when each drive assembly interface element is anywhere within its range of motion.

Abstract: A drive unit for a surgical robot arm, the robot arm being configured to engage a robotic surgical instrument, the drive unit comprising a plurality of drive interface elements, each drive interface element having a longitudinal axis; a plurality of actuators configured to drive the plurality of drive interface elements, each actuator of the plurality of actuators being configured to drive one of the plurality of drive interface elements so as to cause that drive interface element to be displaced along its longitudinal axis in a first direction, wherein the drive unit is configured such that, when the surgical robot arm engages the robotic surgical instrument, the longitudinal axis of each drive interface element is aligned with a longitudinal axis of a respective instrument interface element in the instrument and each drive interface element is configured such that the displacement of said drive interface element along its longitudinal axis in the first direction causes a displacement of the respective instr

Abstract: Described herein are apparatuses and methods for conditioning particles. In some embodiments, the apparatuses and methods are configured for first-in-first-out transit of particles through a chamber containing a conditioning fluid.

Abstract: A robotic surgical instrument comprising: a shaft; driving elements running through the shaft; an articulation at a distal end of the shaft for articulating an end effector, the articulation driveable by the driving elements; and an instrument interface at a proximal end of the shaft, the instrument interface comprising instrument interface elements, each instrument interface element configured to: drive one of the driving elements, and engage a drive assembly interface element of a drive assembly interface of a surgical robot arm when the robotic surgical instrument engages the surgical robot arm such that, when engaged, both the instrument interface element and the drive assembly interface element intersect the line of the one of the driving elements.