Patents by Inventor Peter Christian De Visser

Peter Christian De Visser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DYSTROPHIN EXON SKIPPING OLIGONUCLEOTIDES
    Publication number: 20230348909
    Abstract: Provided herein are antisense oligonucleotides (AONs) that induce skipping of exon 51 of human dystrophin pre-mRNA, and pharmaceutically acceptable derivatives thereof. Also provided are pharmaceutical compositions containing the AONs and methods of using the AONs and compositions for treating a subject with Duchenne muscular dystrophy.
    Type: Application
    Filed: March 29, 2023
    Publication date: November 2, 2023
    Inventors: Steven Michael Froelich, Josh Christopher Woloszynek, Jenna-Marie Magat, Judith Christina Theodora van Deutekom, Peter Christian de Visser, Nicole Anne Datson
  • OLIGOMERS HAVING BICYCLIC SCAFFOLD MOIETIES
    Publication number: 20230330128
    Abstract: The current invention provides antisense splice-switching oligonucleotides with improved characteristics that enhance clinical applicability for treating, ameliorating, preventing, and/or delaying neuromuscular disorders, such as DMD.
    Type: Application
    Filed: March 6, 2023
    Publication date: October 19, 2023
    Inventors: Judith Christina Theodora van Deutekom, Peter Christian de Visser
  • RNA MODULATING OLIGONUCLEOTIDES WITH IMPROVED CHARACTERISTICS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
    Publication number: 20220389421
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Application
    Filed: April 25, 2022
    Publication date: December 8, 2022
    Inventors: Peter Christian DE VISSER, Susan Allegonda Maria MULDERS
  • Substances for targeting various selected organs or tissues
    Patent number: 11459358
    Abstract: The invention provides conjugates, comprising an organ or tissue targeting moiety linked to a biologically active moiety or linked to a diagnostic moiety. Such a biologically active or diagnostic moiety can be, for example, an oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical, or a detectable agent.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: October 4, 2022
    Assignee: ACADEMISCH ZIEKENHUIS LEIDEN
    Inventors: Peter Christian De Visser, Adriana Marie Aartsma-Rus, Silvana Maria Gerarda Jirka, Peter Abraham Christiaan 'T Hoen, Maria Begoña Aguilera Diez
  • RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders
    Patent number: 11345915
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: May 31, 2022
    Assignee: VICO THERAPEUTICS B.V.
    Inventors: Peter Christian De Visser, Susan Allegonda Maria Mulders
  • OLIGONUCLEOTIDE
    Publication number: 20220098586
    Abstract: Provided are splice-switching hydroxyalkoxylated antisense oligonucleotides for preventing, treating, and/or delaying neuromuscular disorders, more specifically Duchenne Muscular Dystrophy.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 31, 2022
    Inventors: Peter Christian de Visser, Judith Christina Theodora van Deutekom
  • Substances for targeting various selected organs or tissues
    Publication number: 20210347825
    Abstract: The invention provides conjugates, comprising an organ or tissue targeting moiety linked to a biologically active moiety or linked to a diagnostic moiety. Such a biologically active or diagnostic moiety can be, for example, an oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical, or a detectable agent.
    Type: Application
    Filed: November 15, 2017
    Publication date: November 11, 2021
    Inventors: Peter Christian DE VISSER, Adriana Marie AARTSMA-RUS, Silvana Maria Gerarda JIRKA, Peter Abraham Christiaan 'T HOEN, Maria Begoña AGUILERA DIEZ
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy
    Publication number: 20210108204
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: Peter Christian de Visser, Judith Christina Theodora van Deutekom
  • RNA modulating oligonucleotides with improved characteristics for the treatment of Duchenne and Becker muscular dystrophy
    Patent number: 10913946
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: February 9, 2021
    Assignee: BioMarin Technologies B.V.
    Inventors: Peter Christian de Visser, Judith Christina Theodora van Deutekom
  • RNA MODULATING OLIGONUCLEOTIDES WITH IMPROVED CHARACTERISTICS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
    Publication number: 20200149043
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Application
    Filed: October 22, 2019
    Publication date: May 14, 2020
    Inventors: Peter Christian DE VISSER, Susan Allegonda Maria MULDERS
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy
    Publication number: 20190194656
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Application
    Filed: November 27, 2018
    Publication date: June 27, 2019
    Inventors: Peter Christian de Visser, Judith Christina Theodora van Deutekom
  • RNA modulating oligonucleotides with improved characteristics for the treatment of duchenne and becker muscular dystrophy
    Patent number: 10179912
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: January 15, 2019
    Assignee: BioMarin Technologies B.V.
    Inventors: Peter Christian de Visser, Judith Christina Theodora van Deutekom
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy
    Publication number: 20180362973
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Application
    Filed: August 9, 2016
    Publication date: December 20, 2018
    Inventors: Peter Christian de Visser, Judith Christina Theodora van DEUTEKOM
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Neuromuscular Disorders
    Publication number: 20180066256
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Application
    Filed: August 14, 2017
    Publication date: March 8, 2018
    Inventors: Peter Christian de Visser, Susan Allegonda Maria Mulders
  • Oligomers Having Bicyclic Scaffold Moeities
    Publication number: 20180028554
    Abstract: The current invention provides oligomers with improved characteristics that enhance clinical applicability for treating, ameliorating, preventing a disorder or disease.
    Type: Application
    Filed: July 5, 2017
    Publication date: February 1, 2018
    Inventors: Judith Christina Theodora Van DEUTEKOM, Peter Christian de VISSER
  • RNA modulating oligonucleotides with improved characteristics for the treatment of neuromuscular disorders
    Patent number: 9745576
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: August 29, 2017
    Assignee: BIOMARIN TECHNOLOGIES B.V.
    Inventors: Peter Christian de Visser, Susan Allegonda Maria Mulders
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy
    Publication number: 20170029818
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Application
    Filed: August 9, 2016
    Publication date: February 2, 2017
    Inventors: Peter Christian de Visser, Judith Christina Theodora van DEUTEKOM
  • COMPOUNDS FOR TREATING, DELAYING AND/OR PREVENTING A HUMAN GENETIC DISORDER SUCH AS MYOTONIC DYSTROPHY TYPE I (DMI)
    Publication number: 20170029820
    Abstract: The current invention provides new compounds for treating, delaying and/or preventing a human genetic disorder such as myotonic dystrophy type 1 (DM1), spino-cerebellar ataxia 8 and/or Huntington's disease-like 2 caused by expansions of CUG repeats in the transcripts of DM1/DMPK, SCA8 or JPH3 genes.
    Type: Application
    Filed: April 8, 2016
    Publication date: February 2, 2017
    Inventors: Maria Begoña Aguilera Diez, Peter Christian de Visser, Susan Allegonda Maria Mulders
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Neuromuscular Disorders
    Publication number: 20150148404
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing, delaying and/or treating a human cis-element repeat instability associated genetic neuromuscular or neurodegenerative disorder.
    Type: Application
    Filed: October 23, 2014
    Publication date: May 28, 2015
    Inventors: Peter Christian de Visser, Susan Allegonda Maria Mulders
  • RNA Modulating Oligonucleotides with Improved Characteristics for the Treatment of Duchenne and Becker Muscular Dystrophy
    Publication number: 20150045413
    Abstract: The current invention provides an improved oligonucleotide and its use for treating, ameliorating, preventing and/or delaying DMD or BMD.
    Type: Application
    Filed: July 28, 2014
    Publication date: February 12, 2015
    Inventors: Peter Christian De Visser, Judith Christina Theodora Van Deutekom