Abstract: Processes for preparing 2'-O-alkylated guanosine, uridine, cytidine, and 2,6-diaminopurine 3'-O-phosphoramidites include the steps of alkylating nucleoside precursors, adding suitable blocking groups and phosphitylating. For the guanosine 2'-O-alkylated 3'-O-phosphoramidites, alkylation is effected on 2,6-diamino-9-(.beta.-D-ribofuranosyl)purine followed by deamination. For uridine 2'-O-alkylated 3'-O-phosphoramidites, alkylation is effect on a dialkyl stannylene derivative of uridine. For cytidine 2'-O-alkylated 3'-O-phosphoramidites, alkylation is effected directly on cytidine. Alkylation is effected directly upon 2,6-diaminopurine.

Abstract: A method for verifying that an integrated circuit design tool kit has not been modified in an unauthorized manner is accomplished by providing a verification procedure that, when an executable subrule of the tool kit has been selected to be part of the rule system, the executable subrule reads a table of time stamps. This table of time stamps and a key are provided, as representative data, to an authentication subrule by the executable subrule. The executable subrule and the authentication subrule perform an authentication check algorithm upon the representative data to produce remotely and locally checked data respectively. The executable subrule then provides the locally checked data to the authentication subrule which compares the locally checked data with the remotely checked data. When a match occurs between the data, the authentication subrule indicates that the executable subrule has not been modified in an unauthorized manner.

Abstract: In order to efficiently execute a complex task within a computer system, the task is partitioned into a plurality of entities. A master process and a slave process are started for each entity. The master processes schedule operations to be performed, while the slave processes perform the operations. One slave process is coupled to one or more other slave processes because of path interconnections between the entities. Communication is established between any coupled slave processes such that one slave process may directly communicate with another slave process without involving the master processes. The master and slave processes execute in parallel on a plurality of processors.

Abstract: 2'-O-alkylated guanosine, uridine, cytidine, and 2,6-diaminopurine 3'-O-phosphoramidites are prepared by alkylating nucleoside precursors, adding suitable blocking groups and phosphitylating. Alkylation is effected on 2,6-diamino-9-(.beta.-D-ribofuranosyl)purine followed by deamination to prepare guanosine 2'-O-alkylated 3'-O-phosphormidites. Alkylation is effected on a dialkyl stannylene derivative of uridine to prepare uridine 2'-O-alkylated 3'-O-phosphormidites. Alkylation is effected directly on cytidine to prepare cytidine 2'-O-alkylated 3'-O-phosphormidites. Alkylation is effected directly on 2,6-diaminopurine to prepare 2,6-diaminopurine 2'-O-alkylated 3'-O-phosphormidites.