Abstract: The present disclosure relates to systems and methods for forecasting weather events, and in particular, for forecasting weather-related impacts on schedules for construction projects and capital programs, or any type of project, program and/or operation where weather can influence its outcome. The disclosed systems/methods can include parsing and processing received project activity data to instantiate an activity model for each schedule activity. A machine-trained classifier can be used to predict, for each respective activity model, types of weather events that are expected to impact each schedule activity. Weather forecast data can also be parsed and/or processed to classify forecasted weather events according to multiple pre-defined types of weather events. A report can be generated specifying which schedule activities are expected to be impacted by forecasted weather events.

Abstract: Redirecting network traffic within a system under test (SUT) can include receiving, within a proxy included within the SUT, a request sent from an upstream component that is directed to a downstream component, wherein the upstream component is configured to direct communications through the proxy. Within the proxy, the request can be redirected from the downstream component to a simulation component according to a routing rule within the proxy using a processor. A response can be received, within the proxy, from the simulation component and sent to the upstream component.

Abstract: Redirecting network traffic within a system under test (SUT) can include receiving, within a proxy included within the SUT, a request sent from an upstream component that is directed to a downstream component, wherein the upstream component is configured to direct communications through the proxy. Within the proxy, the request can be redirected from the downstream component to a simulation component according to a routing rule within the proxy using a processor. A response can be received, within the proxy, from the simulation component and sent to the upstream component.

Abstract: Redirecting network traffic within a system under test (SUT) can include receiving, within a proxy included within the SUT, a request sent from an upstream component that is directed to a downstream component, wherein the upstream component is configured to direct communications through the proxy. Within the proxy, the request can be redirected from the downstream component to a simulation component according to a routing rule within the proxy using a processor. A response can be received, within the proxy, from the simulation component and sent to the upstream component.

Abstract: Redirecting network traffic within a system under test (SUT) can include receiving, within a proxy included within the SUT, a request sent from an upstream component that is directed to a downstream component, wherein the upstream component is configured to direct communications through the proxy. Within the proxy, the request can be redirected from the downstream component to a simulation component according to a routing rule within the proxy using a processor. A response can be received, within the proxy, from the simulation component and sent to the upstream component.

Abstract: Redirecting network traffic within a system under test (SUT) can include receiving, within a proxy included within the SUT, a request sent from an upstream component that is directed to a downstream component, wherein the upstream component is configured to direct communications through the proxy. Within the proxy, the request can be redirected from the downstream component to a simulation component according to a routing rule within the proxy using a processor. A response can be received, within the proxy, from the simulation component and sent to the upstream component.

Abstract: The present invention relates to pharmaceutical compositions containing the antifolate aminopterin, processes for making the compositions, and methods of using them to treat disorders in adult and pediatric patients. Pharmaceutical compositions substantially free of impurities are provided comprising a therapeutically effective amount of aminopterin, or a pharmaceutically acceptable salt thereof. Relative to the teachings of the prior art, the disclosed methods and compositions provide unexpected improvements that include a greater interpatient oral bioavailability in pediatric patients, a smaller interpatient coefficient of variation of oral bioavailability, a smaller mean intrapatient coefficient of variation of oral bioavailability, a greater therapeutic index, a smaller coefficient of variation of toxicity, efficacy in combination therapy, and efficacy of certain polyglutamated metabolites.

Abstract: A metal screened (13) electronic labelling system having at least one information bearing electronic coded label including a label coil (12) and an interrogator including a transmitter coil (9). The system relies on a magnetic field coupling link containing the transmitter coil (9) and the label coil (12) for obtaining information from the label. The coupling link is arranged such that it operates in the near field thereof and substantially none or at most a minority of the magnetic flux which excites the label coil (12) also links the transmitter coil (9).

Abstract: The present invention relates to pharmaceutical compositions containing the antifolate aminopterin, processes for making the compositions, and methods of using them to treat disorders in adult and pediatric patients. Pharmaceutical compositions substantially free of impurities are provided comprising a therapeutically effective amount of aminopterin, or a pharmaceutically acceptable salt thereof. Relative to the teachings of the prior art, the disclosed methods and compositions provide unexpected improvements that include a greater interpatient oral bioavailability in pediatric patients, a smaller interpatient coefficient of variation of oral bioavailability, a smaller mean intrapatient coefficient of variation of oral bioavailability, a greater therapeutic index, a smaller coefficient of variation of toxicity, efficacy in combination therapy, and efficacy of certain polyglutamated metabolites.

Abstract: A system is disclosed for secure communication between an interrogator and an RFID tag. The system includes means for singulating the tag in a population of RFID tags and means for extracting from the tag, identity data adapted to uniquely identify the tag. The system further includes means for securely communicating the identity data to a secure database, means for providing authentication data by the database and means for securely communicating the authenticating data to the interrogator. The system also includes means for providing a further communication between the tag and the interrogator, and wherein at least one stream of data between the tag and the interrogator includes random data generated via a random physical process. The tag and database may each include means for maintaining a count of secure authentications. The count may be separately maintained by the tag and database and may be incremented following each secure authentication.