Patents by Inventor Peter Colon McDonnell

Peter Colon McDonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEGYLATED ABETA FAB
    Publication number: 20100015155
    Abstract: A method to treat conditions associated with A? peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human A? peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule.
    Type: Application
    Filed: January 9, 2008
    Publication date: January 21, 2010
    Inventors: Kelly Renee Bales, Thomas Frank Bumol, Chi-Kin Chow, Ronald Bradley Demattos, Ryan John Hansen, Uma Kuchibhotla, Jirong Lu, Peter Colon McDonnell
  • Protein based tumor necrosis factor-receptor variants for the treatment of TNF related disorders
    Patent number: 7144987
    Abstract: The invention relates to novel proteins with TNF-receptor antagonist activity and nucleic acids encoding these proteins. The invention further relates to TNF-receptor proteins with reduced immunogenicity and the use of these novel proteins in the treatment of TNF related disorders.
    Type: Grant
    Filed: January 3, 2003
    Date of Patent: December 5, 2006
    Assignee: Xencor
    Inventors: Arthur J. Chirino, Peizhi Luo, Peter Colon McDonnell, Umesh Muchhal, Malu Lourdes Tansey
  • Drug binding protein
    Patent number: 6033873
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein CSBP.beta., to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: March 7, 2000
    Assignee: Smithkline Beecham Corporation
    Inventors: Peter Colon McDonnell, Peter Ronald Young
  • Smooth muscle cell-derived migration factor
    Patent number: 5916758
    Abstract: Isolated nucleic acid encoding human smooth muscle cell-derived migration factor, protein obtainable from the nucleic acid, recombinant host cells transformed with the nucleic acid and use of the protein and nucleic acid sequence are disclosed.
    Type: Grant
    Filed: April 23, 1997
    Date of Patent: June 29, 1999
    Inventors: Mark Robert Hurle, Peter Colon McDonnell, Dean Edward McNulty, Craig Alan Rosen, Ivo Rogulia Siemens, Peter Ronald Young, Tian-Li Yue
  • Screening methods using cytokine suppressive anti-inflammatory drug (CSAID) binding proteins
    Patent number: 5871934
    Abstract: This invention relates to methods of screening for pharmaceuticals using Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding proteins.
    Type: Grant
    Filed: April 15, 1996
    Date of Patent: February 16, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: John Cheung-Lun Lee, Jerry Leroy Adams, Timothy Francis Gallagher, David W. Green, John Richard Heys, Peter Colon McDonnell, Dean Edward McNulty, James E. Strickler, Peter Ronald Young
  • Drug binding protein
    Patent number: 5869043
    Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein CSBP.beta., to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.
    Type: Grant
    Filed: November 15, 1996
    Date of Patent: February 9, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Peter Colon McDonnell, Peter Ronald Young