Patents by Inventor Peter D. Burbelo

Peter D. Burbelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND DEVICE FOR DETECTING ANTIGEN-SPECIFIC ANTIBODIES IN A BIOLOGICAL FLUID SAMPLE BY USING NEODYMIUM MAGNETS
    Publication number: 20200166505
    Abstract: Methods for detecting antigen-specific antibodies in a biological sample are described. The disclosed methods can be used for the diagnosis of a variety of autoimmune and infectious diseases. The methods use a neodymium magnet to efficiently isolate immune complexes. The disclosed methods are rapid, highly specific and sensitive, require very small volumes of biological sample, and do not require the use of radioactivity. With these advantageous features, the disclosed methods are amendable for point-of-care testing (POCT), which is currently not available for the detection of autoantibodies associated with autoimmune disease or for the detection of many pathogen-specific antibodies.
    Type: Application
    Filed: January 30, 2020
    Publication date: May 28, 2020
    Applicant: The U.S.A., as represented by the Secretary, Department of Health and Human Services
    Inventor: Peter D. Burbelo
  • Method and device for detecting antigen-specific antibodies in a biological fluid sample by using neodymium magnets
    Patent number: 10564152
    Abstract: Methods for detecting antigen-specific antibodies in a biological sample are described. The disclosed methods can be used for the diagnosis of a variety of autoimmune and infectious diseases. The methods use a neodymium magnet to efficiently isolate immune complexes. The disclosed methods are rapid, highly specific and sensitive, require very small volumes of biological sample, and do not require the use of radioactivity. With these advantageous features, the disclosed methods are amendable for point-of-care testing (POCT), which is currently not available for the detection of autoantibodies associated with autoimmune disease or for the detection of many pathogen-specific antibodies.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: February 18, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventor: Peter D. Burbelo
  • METHOD AND DEVICE FOR DETECTING ANTIGEN-SPECIFIC ANTIBODIES IN A BIOLOGICAL FLUID SAMPLE BY USING NEODYMIUM MAGNETS
    Publication number: 20180267031
    Abstract: Methods for detecting antigen-specific antibodies in a biological sample are described. The disclosed methods can be used for the diagnosis of a variety of autoimmune and infectious diseases. The methods use a neodymium magnet to efficiently isolate immune complexes. The disclosed methods are rapid, highly specific and sensitive, require very small volumes of biological sample, and do not require the use of radioactivity. With these advantageous features, the disclosed methods are amendable for point-of-care testing (POCT), which is currently not available for the detection of autoantibodies associated with autoimmune disease or for the detection of many pathogen-specific antibodies.
    Type: Application
    Filed: August 8, 2016
    Publication date: September 20, 2018
    Applicant: The U.S.A., as represented by the Secretary, Department of Health and Human Services
    Inventor: Peter D. Burbelo
  • Compositions and methods for screening for lyme disease
    Patent number: 9310367
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of infection by a pathogen that causes Lyme disease in a subject.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: April 12, 2016
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Peter D. Burbelo, Adriana Marques, Michael J. Iadarola
  • COMPOSITIONS AND METHODS FOR SCREENING FOR LYME DISEASE
    Publication number: 20150219647
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of infection by a pathogen that causes Lyme disease in a subject.
    Type: Application
    Filed: December 5, 2014
    Publication date: August 6, 2015
    Inventors: Peter D. Burbelo, Adriana Marques, Michael J. Iadarola
  • Diagnostic assays and methods of use for detection of filarial infection
    Patent number: 9068993
    Abstract: The polynucleotide encoding the antigen Wb123 from the filarial nematode Wuchereria bancrofti, the major causative organism of lymphatic filariasis is provided, along with the polypeptide encoded by the polynucleotide. Methods for making the WM23 antigen, recombinant vectors encoding the Wb123 polynucleotide, and methods of detection of the Wb123 antigen through luciferase immunoprecipitation, ELISA and other detection systems are also provided.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: June 30, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Thomas B. Nutman, Doran Fink, Joseph Kubofcik, Peter D. Burbelo
  • Serological screening for HHV-8 infection using antigen mixtures
    Patent number: 8951723
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of active, latent, or prior infection with human herpesvirus 8 in a subject sample.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: February 10, 2015
    Assignee: The United States of America as Represented by the Secretary, Department of Health and Human Services
    Inventors: Peter D. Burbelo, Joseph Kovacs, Michael J. Iadarola
  • Compositions and methods for screening for Lyme disease
    Patent number: 8926989
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of infection by a pathogen that causes Lyme disease in a subject.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: January 6, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Peter D. Burbelo, Adriana Marques, Michael J. Iadarola
  • DIAGNOSTIC ASSAYS AND METHODS OF USE FOR DETECTION OF FILARIAL INFECTION
    Publication number: 20130273111
    Abstract: The polynucleotide encoding the antigen Wb123 from the filarial nematode Wuchereria bancrofti, the major causative organism of lymphatic filariasis is provided, along with the polypeptide encoded by the polynucleotide. Methods for making the WM23 antigen, recombinant vectors encoding the Wb123 polynucleotide, and methods of detection of the Wb123 antigen through luciferase immunprecipitation, ELISA and other detection systems are also provided.
    Type: Application
    Filed: October 31, 2011
    Publication date: October 17, 2013
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Thomas B. Nutman, Doran Fink, Joseph Kubofcik, Peter D. Burbelo
  • COMPOSITIONS AND METHODS FOR SCREENING FOR LYME DISEASE
    Publication number: 20130164759
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of infection by a pathogen that causes Lyme disease in a subject.
    Type: Application
    Filed: March 10, 2011
    Publication date: June 27, 2013
    Applicants: Department of Health and Human Services
    Inventors: Peter D. Burbelo, Adriana Marques, Michael J. Iadarola
  • SEROLOGICAL SCREENING FOR HHV-8 INFECTION USING ANTIGEN MIXTURES
    Publication number: 20110294147
    Abstract: The invention provides compositions, methods, and kits for the diagnosis or detection of active, latent, or prior infection with human herpesvirus 8 in a subject sample.
    Type: Application
    Filed: February 12, 2010
    Publication date: December 1, 2011
    Applicant: GOVERNMENT OF THE U.S.A., AS REPRESENTED BY THE SE CRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Peter D. Burbelo, Joseph Kovacs, Michael J. Iadarola