Abstract: The present disclosure is directed to a system for the treatment of a sleep disorder through stimulation of the hypoglossal nerve or the geniohyoid muscle of a patient, e.g. a human patient. In general, the system comprises three components, namely a sensing component 50, a stimulation component 100, and a control system 200. In some embodiments, the control system 200 may be embedded within the sensing component 50, or the control system 200 may be embedded within the stimulation component 100.

Abstract: This invention relates to biodurable, reticulated elastomeric matrices that are resiliently-compressible, their manufacture and uses including uses for implantable devices into or for topical treatment of patients, such as humans and other animals, for therapeutic, nutritional, or other useful purposes.

Abstract: A craniofacial plating member comprises a fastening member configured and dimensioned to extend over two portions of bone to be mended together. The fastening member defines a plurality of plate holes, at least a first of the plate holes being positioned to be placed over a first bone hole defined or to be defined in one of the bone portions and a second of the plate holes being positioned to overlie a suitable place for a second bone hole defined or to be defined in the other of said bone portions. They first plate hole overlies the first bone hole, and an attachment member is securely positioned in the first plate hole. In accordance with the preferred embodiment, the attachment member is a pin. That pin further comprises a retention member secured to and integral with the pin. The retention member may also further include a barb.

Abstract: A composition and a method for administering the composition to a patient in order to accelerate wound healing, particularly postoperative wound healing. The composition, which essentially comprises ornithine ?-ketoglutarate, is water-soluble and formulated for oral administration in single-dose packets. The method for using the composition for promoting wound healing includes the step of administering the composition to a patient preoperatively as well as-postoperatively in accordance with a prescribed protocol. The composition may be customized to include one or more additional agents that are effective for promoting nutritional health and/or treating a particular medical problem. The composition may also be taken daily by athletes to minimize the healing time of closed wounds such as muscle or tendon tears that occur during participation in sports, even when the symptoms of such injury are subclinical.

Abstract: An aneurysm treatment device for in situ treatment of aneurysms comprising a collapsible member having a first shape wherein the first shape is an expanded geometric configuration, and a second shape, wherein the second shape is a collapsed configuration that is loadable into a catheter. The aneurysm treatment device is capable of returning to the first shape in the lumen of an aneurysm. Some aneurysm treatment devices comprise a spreadable portion and a projecting portion integral with the spreadable portion. The spreadable portion is capable of resting against and supporting an inner wall of an aneurysm, the projecting portion is capable of being gripped by a surgeon to facilitate insertion and positioning of the device. Other devices have relatively simple shapes and can be implanted to a site as a plurality. Treatment methods are also disclosed.

Abstract: A method and apparatus for the non-invasive treatment of varicose veins. The vibrational energy in acoustic waves emanating from one or more source of ultrasonic energy is focused beneath the skin to cause localized heating and tissue disruption and/or destruction in and around the varicosed segment of the vein, particularly the venous endothelium. The localized tissue destruction is followed by localized fibrosis in and around the dilated portion of the varicosed vessel. The ultrasound-induced fibrosis includes thickening and loss of elasticity of the vascular wall. If a sufficiently high dosage of ultrasound energy is delivered to the vein, the varicosed portion of the vessel will be obliterated, providing a therapeutic result similar to that obtained by injection sclerotherapy or vein stripping.