Abstract: The present invention is directed to certain (hetero)aroyl 4-aminopyrazole derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, R1, R2, and R3 are as defined herein, which are potent inhibitors of LRRK2 kinase and may be useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease and other diseases and disorders described herein. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

Abstract: A crosslinkable composition, a crosslinked composition formed upon exposure of the crosslinkable composition to ultraviolet radiation or ionizing radiation, articles containing these compositions, and methods of making the articles are described. The crosslinkable compositions contain two different (meth)acrylate copolymers and can be applied to a substrate using an extrusion process. While being extruded, the crosslinkable compositions advantageously are resistant to crosslinking and/or increased molecular weights. The crosslinked compositions can function as adhesive compositions that are particularly well suited for use in electronic devices.

Abstract: A sequence of data groups are modulated at a central location and coupled to a telephone line in response to a call-up signal. The sequence is transmitted through the telephone lines to a remote computer. The computer receives the signals, demodulates them, and couples them to a moemory. The data is stored at a particular address, and in coupling the data to the memory, the computer checks a flag at that address to determine whether the data has already been written over. When the flags indicate that the data received corresponds to data already written over, it signals the end of a transmission. The data stored in the memory can be accessed by an operator using input controls.