Patents by Inventor Peter D. Ludowise
Peter D. Ludowise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11603559Abstract: A method includes performing a nucleic acid amplification of a nucleic acid sample using a detection probe, wherein the nucleic acid amplification occurs over one or more interrogation periods, and, from the nucleic acid amplification, acquiring amplification data that indicates an amount of nucleic acid present for each of the one or more interrogation periods. The method also includes, based on the amplification data, determining a crosstalk correction value associated with a spectral neighbor to the probe to reduce spectral crosstalk from the spectral neighbor; and applying the crosstalk correction value to amplification data collected from multiplex nucleic acid amplifications of nucleic acid samples.Type: GrantFiled: March 12, 2018Date of Patent: March 14, 2023Assignee: DiaSorin Italia S.p.A.Inventor: Peter D. Ludowise
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Publication number: 20220125982Abstract: Aspects of the present disclosure relate to an electronic device having a housing that includes a major side portion having a curved major surface and an inside major surface, the major side portion comprises a first section and a second section each having different opacities. An aspect of the present disclosure is that the housing is not powder coated, or painted. The electronic device can have a display comprising an array of display elements surface mounted on a rigid printed circuit board such that the array of display elements are planar, a display element from the array of display elements is aligned with the second section such that light is transmitted through the second section and projected onto the curved major surface.Type: ApplicationFiled: March 13, 2020Publication date: April 28, 2022Inventors: Danielle R. Truckenmiller, John W. Cain, Peter D. Ludowise, Sean D. Regan, Benjamin M. Wilke
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Publication number: 20210402033Abstract: Aspects of the present disclosure relate to a reading apparatus that a well formed from a portion of a housing. The well dimensioned to receive at least a portion of a sterilization indicator having spores. The reading apparatus can also have a heating element thermally coupled to a portion of the well and an excitation source to excite the substance in the sterilization indicator. The reading apparatus can have a sterilization indicator activation circuit for detecting activation of the sterilization indicator. The excitation source is positioned such that light from the excitation source is directed into the well. A color sensor can be positioned adjacent the well to receive reflected light from the sterilization indicator.Type: ApplicationFiled: March 13, 2020Publication date: December 30, 2021Inventors: Peter D. Ludowise, Anthony J. Jennen, Barry W. Robole, Leroy J. Longworth
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Publication number: 20190117810Abstract: Process monitoring systems include a reader having a read sensor, an optional reference sensor, and a light source. The reader optionally includes an optical block defining an interior volume and an aperture aligned with the read sensor to allow diffuse light to be received by the read sensor. One or more percent reflectance values may be calculated in response to a dark measurement, a correction function, and normalization. The one or more percent reflectance values may be compared to a threshold to determine whether a disinfection cycle was effective. The reader may indicate the determination to a user and provide the determination to a tracking system for diagnostics, inventory management, or compliance monitoring.Type: ApplicationFiled: April 19, 2017Publication date: April 25, 2019Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: PETER D. LUDOWISE, ANTHONY J. JENNEN, BARRY W. ROBOLE, PHILIP G. DION, LEROY J. LONGWORTH, JAY R. GOETZ
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Publication number: 20180201987Abstract: A method includes performing a nucleic acid amplification of a nucleic acid sample using a detection probe, wherein the nucleic acid amplification occurs over one or more interrogation periods, and, from the nucleic acid amplification, acquiring amplification data that indicates an amount of nucleic acid present for each of the one or more interrogation periods. The method also includes, based on the amplification data, determining a crosstalk correction value associated with a spectral neighbor to the probe to reduce spectral crosstalk from the spectral neighbor; and applying the crosstalk correction value to amplification data collected from multiplex nucleic acid amplifications of nucleic acid samples.Type: ApplicationFiled: March 12, 2018Publication date: July 19, 2018Inventor: Peter D. Ludowise
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Patent number: 9938569Abstract: A method includes performing a nucleic acid amplification of a nucleic acid sample using a detection probe, wherein the nucleic acid amplification occurs over one or more interrogation periods, and, from the nucleic acid amplification, acquiring amplification data that indicates an amount of nucleic acid present for each of the one or more interrogation periods. The method also includes, based on the amplification data, determining a crosstalk correction value associated with a spectral neighbor to the probe to reduce spectral crosstalk from the spectral neighbor; and applying the crosstalk correction value to amplification data collected from multiplex nucleic acid amplifications of nucleic acid samples.Type: GrantFiled: August 31, 2010Date of Patent: April 10, 2018Assignee: DIASORIN S.P.A.Inventor: Peter D. Ludowise
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Patent number: 9725762Abstract: Systems and methods for processing sample processing devices. The system can include a sample processing device comprising a detection chamber, a motor configured to rotate the sample processing device about an axis of rotation, and an optical module operatively positioned relative to the sample processing device and configured to determine whether a selected volume of material is present in the detection chamber of the sample processing device. The method can include rotating the sample processing device about an axis of rotation, and determining whether a selected volume of material is present in the detection chamber, while rotating the sample processing device. In some embodiments, determining whether a selected volume of material is present can be performed by optically interrogating the detection chamber for an optical property of the material.Type: GrantFiled: October 13, 2015Date of Patent: August 8, 2017Assignee: Diasorin S.P.A.Inventors: Peter D. Ludowise, David A. Whitman, Kyle C. Armantrout, Maurice Exner, Lucien A. E. Jacky, Michelle Tabb
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Patent number: 9717812Abstract: A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.Type: GrantFiled: February 18, 2015Date of Patent: August 1, 2017Assignee: 3M INNOVATIVE PROPERTIES CO.Inventors: Sailaja Chandrapati, Jeffrey C. Pederson, Heather M. Webb, Jeffrey D. Smith, Kurt J. Halverson, Bryan S. Behun, Peter D. Ludowise
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Publication number: 20160040213Abstract: Systems and methods for processing sample processing devices. The system can include a sample processing device comprising a detection chamber, a motor configured to rotate the sample processing device about an axis of rotation, and an optical module operatively positioned relative to the sample processing device and configured to determine whether a selected volume of material is present in the detection chamber of the sample processing device. The method can include rotating the sample processing device about an axis of rotation, and determining whether a selected volume of material is present in the detection chamber, while rotating the sample processing device. In some embodiments, determining whether a selected volume of material is present can be performed by optically interrogating the detection chamber for an optical property of the material.Type: ApplicationFiled: October 13, 2015Publication date: February 11, 2016Inventors: Peter D. Ludowise, David A. Whitman, Kyle C. Armantrout, Maurice Exner, Lucien A.E. Jacky, Michelle Tabb
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Patent number: 9168523Abstract: Systems and methods for processing sample processing devices. The system can include a sample processing device comprising a detection chamber, a motor configured to rotate the sample processing device about an axis of rotation, and an optical module operatively positioned relative to the sample processing device and configured to determine whether a selected volume of material is present in the detection chamber of the sample processing device. The method can include rotating the sample processing device about an axis of rotation, and determining whether a selected volume of material is present in the detection chamber, while rotating the sample processing device. In some embodiments, determining whether a selected volume of material is present can be performed by optically interrogating the detection chamber for an optical property of the material.Type: GrantFiled: May 18, 2012Date of Patent: October 27, 2015Assignees: 3M Innovative Properties Company, Focus Diagnostics, Inc.Inventors: Peter D. Ludowise, David A. Whitman, Kyle C. Armantrout, Maurice Exner, Lucien A. E. Jacky, Michelle Tabb
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Patent number: 9121055Abstract: A method comprising acquiring amplification data proportional to an amount of nucleic acid present for each of a plurality of PCR cycles includes applying wavelet transformation to the amplification data to determine a PCR cycle corresponding to a point within a growth period of the amplification data, and updating a display A device including a control module, an analysis module and an interface module for initialization of PCR analysis of a nucleic acid sample, receiving amplification data proportional to an amount of nucleic acid present applying wavelet transformation to the amplification data to determine a PCR cycle corresponding to a point within a growth period of the amplification data, and updating a display based on the amplification data is also provided.Type: GrantFiled: April 24, 2009Date of Patent: September 1, 2015Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventor: Peter D. Ludowise
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Patent number: 9067205Abstract: A system and method for valving on a sample processing device. The system can include a valve chamber, a process chamber, and a valve septum located between the valve chamber and the process chamber. The system can further include a fluid pathway in fluid communication with an inlet of the valve chamber, wherein the fluid pathway is configured to inhibit a liquid from entering the valve chamber and collecting adjacent the valve septum when the valve septum is in a closed configuration. The method can include rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the valve chamber; forming an opening in the valve septum; and rotating the sample processing device to exert a second force on the liquid to move the liquid into the valve chamber.Type: GrantFiled: May 18, 2012Date of Patent: June 30, 2015Assignee: 3M Innovative Properties CompanyInventors: Peter D. Ludowise, Jeffrey D. Smith
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Publication number: 20150165082Abstract: A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.Type: ApplicationFiled: February 18, 2015Publication date: June 18, 2015Inventors: Sailaja Chandrapati, Jeffrey C. Pederson, Heather M. Webb, Jeffrey D. Smith, Kurt J. Halverson, Bryan S. Behun, Peter D. Ludowise
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Patent number: 8969029Abstract: A biological sterilization indicator, system, and methods of determining the effectiveness of a sterilization process. The biological sterilization indicator can include a locus of spores, a reservoir containing a liquid, and a sterilant path positioned to provide fluid communication between ambience and the locus of spores. The reservoir can have a closed state in which the reservoir is not in fluid communication with the locus of spores and an open state in which the reservoir is in fluid communication with the locus of spores. The biological sterilization indicator system can include the biological sterilization indicator and a detection device adapted to be coupled to the biological sterilization indicator. In some embodiments, the method can include assaying the spores for a detectable change in a characteristic, and detecting substantially all of the detectable change.Type: GrantFiled: October 12, 2009Date of Patent: March 3, 2015Assignee: 3M Innovative Properties CompanyInventors: Sailaja Chandrapati, Jeffrey C. Pederson, Heather M. Webb, Jeffrey D. Smith, Kurt J. Halverson, Bryan S. Behun, Peter D. Ludowise
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Patent number: 8931331Abstract: A system and method for volumetric metering on a sample processing device. The system can include a metering reservoir, and a waste reservoir positioned in fluid communication with a first end of the metering reservoir to catch excess liquid from the metering reservoir that exceeds a selected volume. The system can further include a capillary valve in fluid communication with the second end of the metering reservoir to inhibit liquid from exiting the metering reservoir until desired. The method can include metering the liquid by rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the capillary valve, and rotating the sample processing device to exert a second force on the liquid that is greater than the first force to move the metered volume of the liquid to the process chamber via the capillary valve.Type: GrantFiled: May 18, 2012Date of Patent: January 13, 2015Assignee: 3M Innovative Properties CompanyInventors: Peter D. Ludowise, David A. Whitman, Jeffrey D. Smith
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Patent number: 8834792Abstract: A system and method for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The system can further include a cover including a first projection, and a housing. A portion of the housing can be movable with respect to the base plate between an open position and a closed position, and can include a second projection. The first projection and the second projection can be adapted to be coupled together when the portion is in the open position and decoupled when the portion is in the closed position. The method can include coupling the cover to the portion of the housing, moving the portion of the housing from the open position to the closed position, and rotating the base plate about the rotation axis.Type: GrantFiled: November 13, 2009Date of Patent: September 16, 2014Assignee: 3M Innovative Properties CompanyInventors: Barry W. Robole, William Bedingham, Peter D. Ludowise, Jeffrey C. Pederson
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Publication number: 20120291538Abstract: A system and method for volumetric metering on a sample processing device. The system can include a metering reservoir, and a waste reservoir positioned in fluid communication with a first end of the metering reservoir to catch excess liquid from the metering reservoir that exceeds a selected volume. The system can further include a capillary valve in fluid communication with the second end of the metering reservoir to inhibit liquid from exiting the metering reservoir until desired. The method can include metering the liquid by rotating the sample processing device to exert a first force on the liquid that is insufficient to move the liquid into the capillary valve, and rotating the sample processing device to exert a second force on the liquid that is greater than the first force to move the metered volume of the liquid to the process chamber via the capillary valve.Type: ApplicationFiled: May 18, 2012Publication date: November 22, 2012Inventors: Peter D. Ludowise, David A. Whitman, Feffrey D. Smith
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Patent number: D672467Type: GrantFiled: May 18, 2011Date of Patent: December 11, 2012Assignee: 3M Innovative Properties CompanyInventors: Jeffrey D. Smith, Peter D. Ludowise
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Patent number: D677395Type: GrantFiled: September 7, 2012Date of Patent: March 5, 2013Assignee: 3M Innovative Properties CompanyInventors: Jeffrey D. Smith, Peter D. Ludowise
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Patent number: D990687Type: GrantFiled: September 26, 2019Date of Patent: June 27, 2023Assignee: 3M Innovative Properties CompanyInventors: John W. Cain, Benjamin M. Wilke, Peter D. Ludowise