Abstract: Content is organized for brands by selecting a plurality of brand templates. After each selection, a set of properties is generated by applying a portion of settings of the respective brand template, with the remaining settings being overridden with settings for a channel communicating one of a plurality of presentations to a node of a network involved in the communication. The plurality of presentations may include different renditions of the same content. The properties may include sections configured for different focus areas and/or types of content associated with at tags to enable brand-level-targeting. Filters may be identified in the properties. Based on each of the identifications, a property from among the generated sets of properties may be selected based on comparisons with the associated tags.

Abstract: Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.

Abstract: A method for maintaining a penetration rate of a drilling operation, where the drilling operation is carried out by a drilling rig having a hammer drill apparatus. A reference penetration rate for the hammer drill bit is chosen. A starting depth of cut is computed from the reference penetration rate, the measured hammer frequency, and the drill bit parameters. The system measures the actual penetration rate of the drill bit and computes an actual depth of cut. From the actual depth of cut a target bit rotation speed is computed. The target rotation speed is compared to the actual rotation speed, and the rotation speed is adjusted up or down to set the bit rotation speed at a value that will maintain the target rotation speed, notwithstanding changes in hammer frequency or ground conditions.

Abstract: A method for maintaining a penetration rate of a drilling operation, where the drilling operation is carried out by a drilling rig having a hammer drill apparatus. A reference penetration rate for the hammer drill bit is chosen. A starting depth of cut is computed from the reference penetration rate, the measured hammer frequency, and the drill bit parameters. The system measures the actual penetration rate of the drill bit and computes an actual depth of cut. From the actual depth of cut a target bit rotation speed is computed. The target rotation speed is compared to the actual rotation speed, and the rotation speed is adjusted up or down to set the bit rotation speed at a value that will maintain the target rotation speed, notwithstanding changes in hammer frequency or ground conditions.

Abstract: A system and method for drilling a borehole using a drilling rig having a rotary drill bit includes monitoring one or more drilling parameters; determining whether the one or more monitored drilling parameters are within predetermined specifications for one or more of the monitored drill parameters; and, executing an exception control procedure for control of a drilling parameter. The exception control procedure receives an input sensor value associated with a drilling parameter and applies feedback control to establish a scaled error value that is used to compute a setting value for the drilling parameter. The drilling parameters controlled may include the rotation speed of the drill bit, the feed rate of the drill bit, the weight-on-bit, or rotation torque during retraction of the drill bit. A computer-readable database of specifications of drill bits may be provided as a part of the system.

Abstract: A system and method for drilling a borehole using a drilling rig having a rotary drill bit includes monitoring one or more drilling parameters; determining whether the one or more monitored drilling parameters are within predetermined specifications for one or more of the monitored drill parameters; and, executing an exception control procedure for control of a drilling parameter. The exception control procedure receives an input sensor value associated with a drilling parameter and applies feedback control to establish a scaled error value that is used to compute a setting value for the drilling parameter. The drilling parameters controlled may include the rotation speed of the drill bit, the feed rate of the drill bit, the weight-on-bit, or rotation torque during retraction of the drill bit. A computer-readable database of specifications of drill bits may be provided as a part of the system.

Abstract: A system and method for drilling a borehole using a drilling rig having a rotary drill bit includes monitoring one or more drilling parameters; determining whether the one or more monitored drilling parameters are within predetermined specifications for one or more of the monitored drill parameters; and, executing an exception control procedure for control of a drilling parameter. The exception control procedure receives an input sensor value associated with a drilling parameter and applies feedback control to establish a scaled error value that is used to compute a setting value for the drilling parameter. The drilling parameters controlled may include the rotation speed of the drill bit, the feed rate of the drill bit, the weight-on-bit, or rotation torque during retraction of the drill bit. A computer-readable database of specifications of drill bits may be provided as a part of the system.

Abstract: A system and method for drilling a borehole using a drilling rig having a rotary drill bit includes monitoring one or more drilling parameters; determining whether the one or more monitored drilling parameters are within predetermined specifications for one or more of the monitored drill parameters; and, executing an exception control procedure for control of a drilling parameter. The exception control procedure receives an input sensor value associated with a drilling parameter and applies feedback control to establish a scaled error value that is used to compute a setting value for the drilling parameter. The drilling parameters controlled may include the rotation speed of the drill bit, the feed rate of the drill bit, the weight-on-bit, or rotation torque during retraction of the drill bit. A computer-readable database of specifications of drill bits may be provided as a part of the system.

Abstract: A system and method for drilling a borehole using a drilling rig having a rotary drill bit includes monitoring one or more drilling parameters; determining whether the one or more monitored drilling parameters are within predetermined specifications for one or more of the monitored drill parameters; and, executing an exception control procedure for control of a drilling parameter. The exception control procedure receives an input sensor value associated with a drilling parameter and applies feedback control to establish a scaled error value that is used to compute a setting value for the drilling parameter. The drilling parameters controlled may include the rotation speed of the drill bit, the feed rate of the drill bit, the weight-on-bit, or rotation torque during retraction of the drill bit. A computer-readable database of specifications of drill bits may be provided as a part of the system.

Abstract: Method and systems, for processing biological material, that contain a biological material in a vessel; add an aggregating agent to the material in the vessel and allow the material to separate into two or more distinct submaterials; extract one or more of the submaterials from the vessel; automatically transport one or more of the submaterials remaining in the vessel to a filtration device; and collect a resulting target retentate into a target retentate receptacle.

Abstract: Method and systems, for processing biological material, that contain a biological material in a vessel; add an aggregating agent to the material in the vessel and allow the material to separate into two or more distinct submaterials; extract one or more of the submaterials from the vessel; automatically transport one or more of the submaterials remaining in the vessel to a filtration device; and collect a resulting target retentate into a target retentate receptacle.