Abstract: A vehicle includes a chassis, a front axle coupled to the chassis, a rear axle coupled to the chassis, a powertrain coupled to the chassis, a cab coupled to the chassis, a rear module coupled to the chassis behind the cab. The powertrain is configured to drive at least one of the front axle or the rear axle. The rear module is selectively reconfigurable between a plurality of configurations.

Abstract: The present disclosure provides a method of treating hypercholesterolemia and other conditions related to PCSK9 activity, e.g. atherosclerosis, atherosclerotic cardiovascular disease, coronary heart disease, metabolic syndrome, acute coronary syndrome, or related cardiovascular disease and cardiometabolic conditions, by orally administering to the subject an amount of a compound of formula (I) wherein A? is selected from a pharmaceutically acceptable anion, and wherein the amount administered is from about 5 mg to about 300 mg of the compound of formula (I). The present invention is also directed to pharmaceutical compositions comprising a compound of formula (I), including particular salts of a compound of formula (I), and a permeation enhancer.

Abstract: Provided herein are antibodies and methods of use thereof. The antibodies as disclosed herein bind to CD163+ on cells, such as on macrophages. These antibodies can be used in methods of treatment, such as methods of treating cancer.

Abstract: An apparatus and a method provided for spraying a coolant to a work piece include a coolant feed line, at least one delivery nozzle for delivering the coolant, and shielding means which surround at least part of said delivery nozzle. The shielding means are arranged with the work piece to form an essentially closed space, and said shielding means includes exhausting means for exhausting gas from the essentially closed space, and means for keeping the outside of the shielding means at a temperature above the dew point.

Abstract: An apparatus and a method provided for spraying a coolant to a work piece include a coolant feed line, at least one delivery nozzle for delivering the coolant, and shielding means which surround at least part of said delivery nozzle. The shielding means are arranged with the work piece to form an essentially closed space, and said shielding means includes exhausting means for exhausting gas from the essentially closed space, and means for keeping the outside of the shielding means at a temperature above the dew point.

Abstract: An x-ray detector is disclosed that has had all unnecessary material removed from the x-ray beam path, and all of the remaining material in the beam path made as light and as low in atomic number as possible. The resulting detector is essentially transparent to x-rays and, thus, has greatly reduced internal scatter. The result of this is that x-ray attenuation data measured for the object under examination are much more accurate and have an increased dynamic range. The benefits of this improvement are that beam hardening corrections can be made accurately, that computed tomography reconstructions can be used for quantitative determination of material properties including density and atomic number, and that lower exposures may be possible as a result of the increased dynamic range.

Abstract: An apparatus for vaporizing a liquid and heating the vaporized liquid to an elevated temperature. The apparatus has a heat transfer wall having an outer surface for receiving heat and transferring the heat to an inner surface. A wick material is disposed so that a portion of the wick material is in contact with the inner surface and another portion is remote from the heat transfer wall. A wick support in contact with the wick material opposite the inner surface of the heat transfer wall provides structural support to the wick material and further provides a path for vaporized liquid to flow from the wick material. Vaporizable liquid is delivered to the portion of the wick material that is remote from the heat transfer wall and is allowed to migrate to the portion that is in contact with the inner surface. Heat from the inner surface converts the liquid to a vaporized liquid. Optionally, a gaseous fuel may be introduced into the wick support for pre-heating and mixing with the vaporized liquid.

Abstract: A computing-device implemented method for compressing data, where such devices include a computer, personal digital assistant (PDA), home appliance, and the like. The data includes bandwidth intensive information such as that used in video conferencing, MPEG and equivalent types of digital video encoding, multi-media data transfers, and interactive gaming. In one implementation, a 3D model has objects defined therein. Each object is defined according to a data collection, each element within the collection having a first data size. A distance is determined between a reference point in the model, and a bounding box for an object. A data reduction factor is selected based, at least in part, on the distance. The data collection is compressed according to the distance by mapping each data of the first data size to data having a second data size smaller than the first data size. Other compression methods and apparatus are disclosed.

Abstract: A computing-device implemented method for compressing data, where such devices include a computer, personal digital assistant (PDA), home appliance, and the like. The data includes bandwidth intensive information such as that used in video conferencing, MPEG and equivalent types of digital video encoding, multi-media data transfers, and interactive gaming. In one implementation, a 3D model has objects defined therein. Each object is defined according to a data collection, each element within the collection having a first data size. A distance is determined between a reference point in the model, and a bounding box for an object. A data reduction factor is selected based, at least in part, on the distance. The data collection is compressed according to the distance by mapping each data of the first data size to data having a second data size smaller than the first data size. Other compression methods and apparatus are disclosed.

Abstract: A computing-device implemented method for compressing a data model, where such devices include a computer, personal digital assistant (PDA), home appliance, and the like. The data includes bandwidth intensive information such as that used in video conferencing, MPEG and equivalent types of digital video encoding, multi-media data transfers, and interactive gaming. In one implementation, a 3D model has objects defined therein. Each object is defined by plural data points that are transferred from a data provider to a recipient. Typically the provider and recipient are in communication over a network. For a first and a second data point defined in the model, first offsets are determined from the first data point for the second data point. The second data point can then be re-coded in terms of the determined first offsets. The first offsets are coded to require less data storage than required for the first data point, thus allowing them to be transferred more quickly.

Abstract: A computing-device implemented method for compressing data, where such devices include a computer, personal digital assistant (PDA), home appliance, and the like. The data includes bandwidth intensive information such as that used in video conferencing, MPEG and equivalent types of digital video encoding, multi-media data transfers, and interactive gaming. In one implementation, a 3D model has objects defined therein. Each object is defined according to a data collection, each element within the collection having a first data size. A distance is determined between a reference point in the model, and a bounding box for an object. A data reduction factor is selected based, at least in part, on the distance. The data collection is compressed according to the distance by mapping each data of the first data size to data having a second data size smaller than the first data size. Other compression methods and apparatus are disclosed.

Abstract: An environmental scanning electron microscope is provided which is capable of only detecting backscattered electron signals emanating from the specimen with the detector assembly be positioned within the gaseous environment of the ESEM specimen chamber. This detector assembly includes a biased converter plate and a collection grid/collection plate/collector ring arrangement. The primary beam passes through the final pressure limiting aperture formed in the converter plate and then through a central aperture of the collection grid/plate/ring before striking the sample. The collection grid is held at ground potential and therefore does not collect secondary electron signals generated at the sample. The backscattered electrons are not collected by the collector grid/plate/ring and strike the converter plate creating converted backscattered electrons. The converted backscattered electrons are amplified in the gas by the electric field created between the converter plate and the collection grid.

Abstract: A stabilizer compound for synthetic resinous materials is a tri-substituted triazine in which each substituent is a N.sup.4 -methylated 2-keto-1,4-diazacyclohexane connected to the triazine ring through an alkylene bridge. This bridge permits efficient methylation of the N.sup.4 atom in every substituent under conditions which yield crystals having at least 90% purity. These crystals may be further purified to at least 95% purity at which purity level they contain less than 500 ppm ash. The stabilization effect of 95% pure compound in a polyacetal is such that, even with an ash content of 50 ppm, it has better stabilization properties than its 99.2% pure precursor (the non-methylated tri-substituted triazine) with an ash content of 10 ppm, as evidenced by lower formaldehyde evolved and better color retention, that is, developing less color in a water white sample after testing at 259.degree. C.

Abstract: A control system for radiation tracking apparatus comprises:(a) photo sensors to receive incident radiation,(b) edge means to intercept radiation directed toward each sensor so that primary and secondary locations on each sensor respectively receive and do not receive incident radiation, the sensors controlling tracking movement of the apparatus,(c) the sensors being electrically energized and having electrical outputs which vary a function of radiation interception by the sensors, and there being means responsive to said outputs to control said tracking movement,(d) and there being control means connected with the sensors and responsive to increases and decreases in the intensity of said radiation to respectively decrease and increase electrical energization of the sensors.

Abstract: A control system for radiation tracking apparatus comprises:A. a shadow box having a window,B. four photo sensors located within the box to receive incident radiation passing through the window,C. first and second sensors respectively having upper and lower locations to provide outputs controlling elevational tracking movement of said apparatus, andD. third and fourth sensors respectively having left and right locations to provide outputs controlling azimuthal tracking movement of said apparatus.